i wanted to share some insight... i recently went to a plastic surgeon's office to get some info on melasma. in my area i have heard the nurse is very insightful. anyways, she said she went to a seminar and she asked the dr about melasma and he said he has patients that are doing the msm (6000 mg) and having luck. they are also combing it with grape seed extract (500 mg). i have been doing this for almost 2 mo now and having some slight fading. i have been only taking 100 mg but will up my dosage asap!! i wanted to share this info as we need as much as we can!!!