These postings have been so helpful. I have had melasma for years now and only just learned what it is. I just assumed it was sun damage and that there was nothing I could do about it. It is most noticeable on my upper lip but I also have it above my nose and below my eyes. When I read this information I immediately started on MSM and grapefruit seed extract. I tried to do a before picture but couldn't capture it well so in the first week when I noticed a small clear patch on each side of my upper lip I thought maybe it was my imagination. Now I am 2 1/2 weeks into the process and I have much larger clear patches so I know it is not my imagination. It is by no means gone but it is definitely going away. I was going to wait to post but realized any progress is progress and if my adding that it is working for me could help someone else then that would be a good thing. I take 1000mg of MSM and 250 mg grapefruit seed extract (in pill form) 3 or 4 times a day. So basically with every meal and if I remember I take an extra dose before bedtime. I will check back in. Thank you to everyone who has posted and good luck to everyone just beginning to try!