Asthma and Grape Seed Extract

To further update on my friend who had good success using Grape Seed Proanthocyanidin Extract (GSPE) for her Asthma, she recently went for a checkup and her doctor told her "that she no longer has asthma." He asked her if she was sure she had wheezing as part of her symptoms and she confirmed to him that she did have it and she had it when she was diagnosed. He also told her that that seems very unlikely for her asthma to be gone and so he scheduled her for further testing to now try and confirm she no longer has it. Hers was adult onset asthma. She told me she no longer has any of the symptoms she had when she was diagnosed.

On a related note, another friend, well actually the daughter of a friend, who has had asthma since she was a child and is now in her late 40's is going to start testing GSPE and her mother said she will update me if her daughter actually takes it and sees improvement because she had to buy the supplement for her daughter because her daughter wouldn't bother getting it herself, in the hope that she would try it for her asthma. According to my friend, her daughter has severe attacks where she sometimes end up in the emergency room. Overall, I won't be holding my breath waiting for her to get back to me, because she has no idea if her daughter will even take it and she doesn't see her that often. Art

I just read Art's article this evening and ordered a bottle. I won't mention a brand unless you ask but my go to for any supplement is Organic if possible.

To update on my friend with adult-onset asthma, in her last conversation with me, she still has not required any use of her asthma inhaler and reports "feeling normal."

To add further confirmation to the idea that GSPE can be helpful for asthmatics, the following study in humans seems to have a similar line of thought :

https://onlinelibrary.wiley.com/doi/full/10.1111/resp.14149_95

Here is a relevant quote from the study :

>>> ' We found that the Nrf2-iNOS-HDAC2 axis was related to glucocorticoid resistance. Further studies showed that IL-8, MCP-1 and iNOS were positively correlated with severe asthma, while Nrf2, HDAC2, GSH, GCLM and Nrf2-ARE binding ability were negatively correlated with severe asthma. GSPE could relieve glucocorticoid resistance by targeting the Nrf2-iNOS-HDAC2 axis, and increased the therapeutic sensitivity of severe asthma. ' <<<

Art

ivybridge,

Thank you for the information on polyphenol content. Could you link to the product that costs less and contains 95% polyphenols? I think that would be useful for the EC community who are interested in using GSE to know.

I am not recommending the product I mentioned, just relaying what worked for my friend, to Stephanie who had asked for a recommendation that I did not have.

Thank you!

Art

I looked at the Carlyle brand and I did not like the label either, fails to mention that the extract is only 70%.

The Carlyle Standardized Grape Seed Extract is standardized to the lowest percentage of these type of products at 70% polyphenols. (280mg/400mg =70%) Better products that cost less per capsule contain 95% total polyphenols. (380mg/400mg = 95%) Look for "Min. 95% total Polyphenols" for a higher quality product IMO.

Hi Stephanie,

My friend is taking Carlyle Standardized Grape Seed Extract

I find the label a bit confusing because they list 24, 000 mg per serving on the front of the label which I believe is supposed to be their idea of a non extract powder equivalent dose. On the back of the label they list 1200 mg per serving, which is 3 capsules per day, but this is the extract form. I can't say with certainty, but the 24, 000 mg number seems a bit misleading. The bottle contains 240 quick release capsules and at the recommended label dose of 3 capsules per day with food, which she is using, the bottle will last 80 days at a price of $16.99.

Here is a link to buy from :

https://carlylenutritionals.com/products/grape-seed-extract-24-000-mg-capsules-240-count?variant=39425027637408¤cy=USD&utm_medium=product_sync&utm_source=google&utm_content=sag_organic&utm_campaign=sag_organic&gclid=Cj0KCQjw5ZSWBhCVARIsALERCvzKLOo98Md7p7p7y9O4jnxsJ1PQD-xiRRXciEP7tQ3ij59dvvXQuU8aAgduEALw_wcB

Please give us your feedback if you try this product for your asthma as you are different than her in that you have had asthma for many years whereas she was only recently (this year) diagnosed with adult onset asthma. Good luck and I hope it is helpful for you as it was for her.

On a related note, she mentioned that she had a really uncomfortable "heavy feeling " in her chest. In my last conversation with her, she said that feeling is completely gone and she has not had to use her inhaler at all since she last mentioned that she had not used it for two day in a row.

Art

Art, thank you SO much!!! I have had asthma most of my life and things have been much worse after "the virus"... Would love to help my lungs! :) Thanks

Stephanie,

I don't have a brand to recommend, but I will ask my friend what brand she used, since it worked well for her and report back once I have that information.

Art

In response to Art Solbrig's new article on Grape Seed Proanthocyanidin Extract for asthma. Please can you share where I can pick up the supplement in a clean version with that high a dose? I am having trouble finding a brand that I could trust.

Hi Chris,

They are not the same or equivalent. GSE possesses some of the most beneficial components of the grape vine while the oil is more like other vegetable oils and happens to have vitamin E in it. As oils go, virgin olive oil would be considered to have more healthy components than grape seed oil. Grape seed oil would not have the same positive health effects as GSE.

Art

Is there a difference between grape seed extract and grape seed oil?

Chris, Adelaide Australia