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The following newer article (March 2023) reviews multiple studies regarding using Melatonin to improve alopecia.
Here is a relevant quote from the article :
' Eleven studies which detailed evidence of melatonin use in patients with alopecia were included. Overall, data for 2,267 patients — including 1,140 men — made the final analysis.
Results showed that eight studies demonstrated positive outcomes for patients with androgenetic alopecia who were treated with topical melatonin.In addition, eight studies also showed an improvement in scalp hair growth with melatonin treatment, whereas four studies demonstrated that melatonin improved scalp hair density compared with controls. An additional two studies showed that melatonin bested controls in terms of hair shaft thickness.
The range for an optimal melatonin dose may be 0.0033% or 0.1% applied as a once-daily regimen for a duration of 90 to 180 days. Additionally, optimizing the vehicle for topical melatonin — for example, with nanostructured lipid carriers — may further improve the hormone's impact on hair growth. '
Art
