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Prurigo Nodularis Remedies

Last Modified on May 09, 2016

While prurigo nodularis is somewhat difficult to treat, many natural treatment options have been identified as effective. Bath soaks, exposure to sunlight and certain dietary changes offer relief from outbreaks of the condition. Certain natural oils, such as emu oil, are effective for softening and relieving the skin.

What is Prurigo Nodularis?

Characterized by firm, itchy lumps on the skin, prurigo nodularis is a progressive skin condition. Lumps generally range in size from 1 to 3 cm in diameter and have a raised, warty appearance. The condition often begins as a somewhat small, red , itchy bump that spreads to include more lesions. The cause of the condition is unknown at this at this point but scratching does exacerbate the disorder.

Home Remedies for Skin Lesions

Eliminating infection, minimizing itching and reducing inflammations are all important factors in treating prurigo nodularis. A variety of home remedies have been identified as effective for treating the condition. Salt baths, sunlight and dietary changes are among the most effective treatment options available.

Salt Bath

A bath in sea salt or even a trip to the ocean is an effective treatment option for minimizing prurigo nodularis. During a soak, the salt water penetrates the pores and is absorbed into the blood stream. This salt helps remove accumulated lactic acid in the body, eliminated infection and dries out sores.


Exposure to the sun also has a rehabilitating effect for treating prurigo nodularis. When exposed to the sun, the skin releases a compound called nitric oxide, which helps stimulate blood flow and lower blood pressure. This compound also functions to remove toxins from the blood as it enhances blood filtration.

Dietary Changes

Dietary changes are another component used to manage this skin condition. Identifying and eliminating trigger foods is the goal for treating the condition through diet. Many individuals benefit from limiting soy lecithin, artificial sweeteners and gluten.

Nodular prurigo is an aggressive skin condition that manifests as very itchy firm lumps on the skin. While it is a condition that is relatively difficult to treat, many natural options offer relief of the condition.

Remedies for Prurigo Nodularis

The Popularity of Prurigo Nodularis Remedies - Full List

Alphabetical Popularity Recent Post
Alcohol Treatment12015-07-01
Anti-Viral Medication12015-09-05
Anti-Viral Medications12014-06-17
Ayurvedic Herbal Treatment12015-11-04
Nodular Prurigo02014-08-10
Salt Baths, Sunlight12013-03-21

Alcohol Treatment  

5 star (1) 

Posted by Anelissa (Brisbane) on 07/01/2015
5 out of 5 stars

A home remedy that inhibits nodular prurigo virus inside skin.

I am careful to write "inhibits" rather than kills, because my current experiment is just four to five days old, and can be considered as an effective treatment, not an actual cure until such time as when I might report that all of my lesions have gone and no further lesions form in the next three months. A friend gave me a bottle of vodka brandy after I told him I might try drinking a few Brandy Alexanders to see if any change occurs with my skin lesions. I barely drank any cos I am not really a drinker. So the bottle sat around for past four months. until four days ago when I decided to dab some on to my scalp where I had been plagued with recurring plaques for the third time inside two years. This last phase beginning last christmas til now.

To cut a long story short, I am overjoyed to be able to tell you that my scalp feels totally rejuvenated. there is still one tender spot to touch, but in the space of less than four days, all plaques are gone from my scalp and now I am dabbing the alcohol on the several spots on face plus a couple on left shoulder. After two days these areas already look so much better. also I bathe mob once a day. Use aveeno. One does still need to pick clean the area, but it works easier after annihilating the virus.

Replied by Richard Murby
Hello, I'd like to try this treatment, but I'm not sure what "Vodka brandy" is. Is it just a mixture of the two? or perhaps a type of clear brandy similar to the French "Eau de Vie" or the italian "grappa" ie, a spirit made from grape pulp after wine fermentation? I've tried to find it on the net, but all I come up with is a cocktail using a mixture of Vodka and Brandy.
Replied by Patti
Oklahoma City, Oklahoma
Hi, my mom has this horrible condition. I'm inquiring as to whether your case has subsided. Thanks.
Replied by Keith
East Yorkshire U.k
Could you please give me more details. I've had 5months of maybe 2 hrs sleep and get more of them every day. I've been taking 100mg azathioprine for past 4 months with no results. Whole body apart from my face is covered. I would be eternally grateful if you could even offer the slenderest hope. I've had it jut over a year, diagnosed 5 months ago and been unable to work for last 4 months. Best Regards, Keith

Anti-Viral Medication  

5 star (1) 

Posted by Amy (Florida) on 09/05/2015
5 out of 5 stars

I suffered with Prurigo Nodularis for 5 months. I was given steroids, shots, antibiotics. I found a forum in the UK that said to try Valtrex. I had sores all over my body. The first wk on Valtrex I saw fast healing, by 2 wks my face , back, chest, arms were clear. 4th wk legs almost clear the last thing to clear were my feet and they were awful looking. I suffered for so long and I have scars everywhere if only I took Valtrex first! I just want to spread the word! I took 2 500 mg a day for 4 wks. I hope I can help someone else.

Replied by Debi
Is Valtrex working? It makes me sick to take it but it would be worth it if it works. I can't find any articles on it being viral. I go to Mayo Clinic and they haven't mentioned Valtrex.

Please let me know if it's working! Thanks in advance for your response.

Anti-Viral Medications  

5 star (1) 
2 star (1) 

Posted by Barb G (Naples, Fl) on 06/17/2014
5 out of 5 stars

My PN started with 31 squamous cell cancers over a period of 3 years. Got rid of those with surgeries, radiation and scrape and burn. It stopped for a year after I took Soriatane for 4 months...had to stop that med because my hair started falling out. But no more cancers for a year. The next 7 biopsies came back as PN. I tried a lot of remedies I found in this forum. Got depressed and went to a psychiatrist who gave me amytriptoline and klonopin for the itching and depression. The next visit he said he researched PN and prescribed Valtrex as most of the PN was on major nerve lines and thought this might be a virus related to shingles. First 1000mg then 2000mgs per day the next month. Eureka! No new PNs and all the rest of the 39 I had are shrinking, drying out and turn white and peel off. Most are gone but the larger ones are white and peeling off.

I truly think this is viral. That's probably why tea tree oil helped some people.

As background...I also had MRSA from one of the squamous surgeries...and pseudemonas Aer...something after a MOHs surgery with a skin graft. One Doc gave me doxycycline IVs and I think Vancomycin for one of the infections. I noted several people online had MRSA and had one or two of these drugs. Maybe they set you up for PN...?

Another thing that helped was a chemo liquid for skin cancer called 5 only kills abnormal skin cells and helped stop the itching of PN and dried out the sores.

I recently had a painful reaction to the 5 FU on a fast growing bump. I had it biopsied and it was squamous cell cancer. This happened before I took the anti viral meds. A new dermatologist is going to try acutane next month for the prevention of any new cancers. I hope this helps someone.

Replied by Anelissa
Thank you for recommending valtrex. I will ask my doctor to prescribe that for me, as I have been thinking it is virus related. Eliminated bacterial cause by using three different antibiotics. Virus makes total sense to me.
Replied by Anelissa
I just want to kiss you Barb G of Naples.

I have made an appointment with my doctor tomorrow to receive a script for Valtrex. Let you know how it goes.

Replied by Samantha
Good afternoon Anelissa, I was just wondering if you were able to meet with your doctor and have started on the Valtrex RX? Can you provide any feedback from your experience?
Replied by Anelissa
Brisbane, Australia
Hi, I have completed 2 packs x 30 tablets,

2 x 500mg per day, and after 1 month of use, my NP has reduced by at least 60percent on upper body, and by 70percent on scalp. Continuing the script for another 14 days. Looking very promising. Cheers, Anelissa

Replied by Ng
California, US
So apparently I went to 2 doctors that thought the bump on my elbow was psoriasis. Well it wasn't! It was prurigo nodularis. Steroids creams were ineffective after use for about 3-4 years. Finally went to a good doctor and he used a injection at the site for itch (good for about the month). Within a week...the bump became smooth/flat and it's starting to get better! Wish I knew earlier. I've also been using palmers cocoa butter...which offered amazing itch relief (even better than steroid creams! )..and I felt like it stays in the skin longer.
Replied by Valencia
Atlanta, GA
2 out of 5 stars

Side Effects:
Thank you so much for posting. I have been using a topical steroid for my Pruigo Nodularis and have developed severe skin damage -- yet another skin issue! I will talk to my doctor about Valtrex immediately. I have been taking Prednisone on and off for the last year and that provides temporary relief. As soon as I come off , I start the burning and itching again. I am also taking 150 mg of Imuran since the middle of August. I don't see any difference.

Replied by Scott
Naples, Fl
I also have PN. It started 15 months ago and has not improved after months of mirtazapine to reduce itching and soaks followed by Triamcinalone application. You have mentioned "5 FU". I am wondering if you are referring to Efudex. Please clarify this for me. Thanks.
Replied by Mary
Naples, Fl
Hello Barb G. I have an almost identical situation; multple MOHS and I had a Staph infection which preceeded a bad case of PM. I have tried everything my Dermatologist has recommended though I haven't tried Valtex. May I ask if the Valtrex continued to clear up the PM? I have had this for over 18 months now and will try almost anything. Thank you.
Replied by Maria
New York, US
HELP! I Was recently finally diagnosed w PN. although Ive had it on /off for about 18 months. I went to 5 diff dermatologists who all told me I have dry itchy skin, never diagnosed me last april I went to a derm in NY known for eczema cures, he did a biopsy found nothing. I suffer from eczema/dermatitis time to time over the years so this was caused by and eczema breakout which I believe happened due to my allergies. Now I just went to another new dermatologist, who has diagnosed me with this . All he has me doing is using to diff topical steroid creams switching every two weeks and cerave cleanser and moisturizer. I've noticed an improvement but it hasn't fully gone away. I have been put on predisnone time and time again on /off which I hate. As soon as I stopped the predisnone I had a breakout w / vengeance like not other on my upper arm this time. Before my PN was only on my forearms. Now my whole upper arm is covered, and there must be at least 20 on my upper arm. The steroids are not working that well. I've decided to try cryotherapy. Hopefully it works , my derm wants me to stay on the steroids for amonth then consider light therapy. I need to be over with this.
Replied by Anelissa
I've now seen how this virus can move around in deep skin tissue. Every so often one gets trapped inside a hair follicle, along with other debris. The follicle swells up like several times its size. And the area inflamed and starts itching. Only a bit of rubbing action is enough for the follicle to snap off at its base, and the follicle with the gunk in the follicle enclosed like sausage meat, does a neat spiraling upward trick, whereby the two ends of it are pointy like pins and can dig their way back deeper into the skin. With or without rubbing , it positions itself so that it can bring its ends together and thereby seal itself like a circular tube, with the virus nicely protected inside it. The surrounding skin now itches a lot and very quickly the tube circle becomes harder and harder, beginning to form a plaque. The tube gets rock hard like finger nails. It takes weeks to pick it out even tho its so near the surface. To make matters worse, the tube contains keratin and whatever else making it a sticky Slough inside the well or centre area of the circle that is the tube. Anyhow, what the alcohol does is kill the virus, and that lowers the inflammation immediately. But to get satisfaction you still scratch around the area to pull bits of the hardened tube out. In the absence of medication that destroys this virus and its fortifications, it's unfortunate that It requires a gauging action to get the hard tube out. perspective.(above) Next: how I have eliminated the virus from my scalp.
Replied by Hyman
Hong Kong

How's your progress of using Valtrex to treat? I really want to know your result and the details. How long does you take the pills? The dose? And does the NP come back after stopping the treatment?


Replied by Jennifer
Nipomo, Ca
Anelissa from Brisbane,

You are very knowledgeable about this. I was diagnosed yesterday and am very sad that so little is being done to understand the cause of this and solve this condition. I am wondering about the plaque you mentioned. Is it a white fibrous looking tissue that forms as the sore is "healing"? The dermatologist said it is protein?? What do I do when it is in this stage? I am currently on a topical steroid (that seems to do nothing). I heard that Emuaid works on healing the sores quicker, but does the Valtrex stop them from returning? I am so thankful that I found this site. I am sad to hear that you all are suffering from this, but glad to hear that I am not alone. I have also found that even when I get a scrape from something totally unrelated (scraped my shin on a boulder), as it is healing, it also turns into one of these white, hard scabs. It must have something to do with the way our bodies are laying down and forming new cells and tissues. Does any Brandy work or does it have to be a specific type?

Replied by Debi
Please let me know if the Valtrex worked. It's making me very sick but will be worth it if it works. I've been going to doctors for this for 3 years and they have never suggested it. Thanks for any help you can give me.

Ayurvedic Herbal Treatment  

5 star (1) 

Posted by Rukhsana (Uk) on 11/04/2015
5 out of 5 stars

I was diagnosed with Prurigo Nodularis in November 2012.. Mainly on my upper back, elbows and buttocks. I've had all the steroid creams, antibiotics, doxycyline, doxipin, oxytetracycline from which I got temporary relief.. I've been to dermatologists twice ..had biopsy done, more steroid creams doxipin.. Two months ago I had a flare up, same cycle went back to drs.. This time I was given fluixillin (antibiotics) and predenisone (steroids) for a week. The sores healed up very quickly and itching went magically. After two weeks it came back with a vengeance and now it spread to my lower back and legs, scalp start peeling and all my private area .. With intensive itching day and all night. Now I got severe psoriasis and prurigo nodularis. Barely got 2 hours sleep. More steroid creams .. Its a vicious cycle...

I decided enough and rang my family who live in Pakistan.. My late grandfather was a well established herbalist (Ayurvedic). I cried and told them my situation and asked if they knew any cure .. They told me that they remember my uncle had it years ago and my grandfather treated him .

I was told to stop all chemically stuff and start on herbal treatment as this will cure it from the roots and will never return.. I was willing to try anything. I was asked to source an Ayurvedic named Gandhak (detoxified sulphur). I suggest you do your own research. It took me days to find a herbalist here in UK who sold it...and he confirmed my aunt's suggestion for treating this skin disease..apparently when I researched it further I discovered this is what homoeopaths give to their patients for skin conditions too but very low doses. So patients keep going back for ages. I've seen it in a well known British store in the homeopathic section.

I managed to get 250 grammes powder from UK. My aunt told me to take one level teaspoon in morning and one at night on an empty stomach with a cup of whole warm milk that should have a teaspoon of clarified butter mixed into it.. So I put the gandhak in my mouth it feels very dry as its powder and then I quickly drink milk over it (very important to take the milk mixture with it).. I was skeptical ..

I'm on day five and what a difference, everything is starting to dry up.. The itching is still there but I was told it would take while to go down and be patient.. I have never seen it healing so quickly in the 3 years. I'm amazed. So take it for 7 days then miss 4 days then 7 days miss 4 days keep repeating this pattern until it dies down.. Shouldn't need to take it more than 6 to 8 weeks.

I was also told to take a teaspoon of evening primrose oil in morning and teaspoon of blackseed oil at night as this moisturises your body from the inside.. So does the milk and butter mixture.

It's early stages but I can miraculously see it working.. My aunt said do not have a soak in the bath as this keeps the wounds seeping, instead have a bucket bath or shower Twice a day. Final rinse should be to put 2 caps dettol into a bucket and pour on yourself (this might not work for all its to help to reduce itching). If you've got it on your scalp then pour the dettol mixture from head to toe.

Come out of shower/bath then put evening primrose oil mixed with wheat germ oil and massage it in ... I'm so relieved and shocked at the difference its made...aunt told me to remember ayurvedic medicines take longer to work but get the disease from the roots unlike steroid creams tablets which are temporary and poison our bodies.. I've also been told to purify my blood from all the toxins I. Have taken in using medicines over these three years

.. It's called neem(from a neem tree)

I got neem powder boiled 50grammes in 300 grammes of water until it halved in consistency. Sieve this and take two tablespoon in morning and two at night with loads of water as it is the most bitterest thing I have ever tasted .. It takes some getting used to..but it purifies your blood is anti fungal, antibacterial etc is the gandhak I hate taking this the neem its so bitter. But I'm going to persevere..

You are welcome to contact me through this post if I can help anyone I will and am willing to update my progress...

Please do your own research on gandhak and neem and take it at your own decision..

I felt I had to post this because of the suffering I've gone through over these three years and could see no end to it.. And hopefully it might help others.

Also lather yourself with mixture of equal amounts of mustard oil evening primrose oil , wheat germ oil and raw organic coconut oil.all over ..massage it well into the skin to keep it moist and to help with itching


Replied by Preeti
Hi, heartening to hear u found a solution. I'm suffering from last 30 years and it's been pretty severe last 5 years. Have not found any solution yet. How r u now after the Ayurvedic treatment. Should I try that..n how?
Replied by Jacks
How is the treatment going?
Replied by Shiraz
Al Manamah

Is it possible to mail you re your experience with NP- and Gandhak. My father is suffering from NP and I have a few questions. Thanks, Shiraz

Replied by Rachel
Hi thank you for sharing this. Just curious if it's this therapy has continued to help you. I unfortunately have had this for yrs and have tried almost everything with no improvement. Thank you!
Replied by Nidhi
Hi Rukhsana, Thanks for your post. I am suffering from same prurigo since last two years. I have eczema since last 15 years. But now it's converted in more horrible conditions. As you know , can't control itch. Whole day and night as well. Have tried all steroids creme, orally also. Nothing worked for me. Just want to know that is there any side effects for taking gandhak orally. I have constipation and severe acidity problems. So big worry to start it. I already have gandhak powder (yellow color) which bought it from India from Ayurvedic store. Can I start with that? Thanks
Replied by Eeti
Hi I just wanted to ask you if there is any improvement with sulphur. Please reply if you consider this treatment worth trying for others.
Replied by Martina
Toronto, Ontario
I am wondering if you have been cured.

Nodular Prurigo  

Posted by Anelissa (Brisbane, AU) on 08/10/2014

The home remedies you list for Nodular Prurigo are pretty useless. In fact, sunlight made my rash worse. Doxycycline dispelled the erythema, but didn't overcome the NP.

I am glad for your webpage, because I was running out of ideas and one of your posters has led me to try Valtrex anti-viral medication, so I'm feeling very excited about this. My condition was misdiagnosed by at least 5 doctors and two specialist since January 2012, only 1 GP was adamant about NP. Finally a third biopsy in March 2014 came back with NP as per Pathology Lab result. Consider if this is a virus, how it may be transmitted via blood transfusion - I'm no expert in immunology, so it's more of a query than a caution. Number of cases of NP are springing up all around me. Just saying, if a virus, then we should be so lucky as to know of one anti viral med that was a success in the cure for NP. Regards Anelissa (pseudonym)

Salt Baths, Sunlight  

4 star (1) 

Posted by Louise (New York) on 03/21/2013
4 out of 5 stars

Remedy for Prurigo Nodularis:

I have had this skin disease for years. The only thing that has worked for me is a combination of salt baths and sunlight. During the winter months, when I can't get to the beach, I put sea salt in my bath and soak in it. It clears up infected sores and dries them out and they form a crust which can be pumiced off with an emery board of callus pumice. It also helps to decrease the itching and therefore the scratching as well. When the weather gets warmer, I lie in the sun. Sun exposure is the best treatment. I have gone from approximately 200 sores on my arms and legs to about a dozen.

Replied by Cathydinmo
Blue Springs, Mo, USA
I've had Prurigo Nodularis 27 years now. I had read something interesting. Have or do any of you had throat or tonsil conditions?
Replied by Mm
Virginia Beach, Va
I seem to have this skin condition. I have hyperthyroidism. I went through a very stressful situation when I started getting the itch. It started on my arm. Initially the itch looks like a bug bite. It was very itchy. The more I scratch, the itchier it gets until it turned to be an open wound. Then I started noticing that the top portion of the itchy wound is filled with fluid. The itching didn't stop. I was placed on Prednisone for 10 days and the itching ceased but then I started to develop itch on my legs and lower back. I need the itch to go away. Dr don't seem to know what it is.
Replied by Lindab
Vancouver Bc Canada
I've had Pruigo Nodularis for over 3 years now on my cheek, started after a bout with shingles followed by 3 years of extreme stress.......I just came back from a dermatologist who told me to keep Vaseline on it...I've been doing that for 10 days now, I put a bandaid over the Vaseline at night & during the day if I'm not going out anywhere. End result is that it's looking much better! .....Don't know if anyone has been able to get any of the nodules out but I have and thought they were tiny cysts.....I have a family history of asthma and hay fever, but don't have that myself....I also have hypothroidism.......I'm hoping that the Vaseline treatment will help in the long run. Before I saw the Dr I had started putting on Nivea Q10 nightcream which also helped....seems these things need a good heavy duty moisturizer which seems to keep the itch away.