Here's some very useful information on Hashimoto's and Graves disease that might help people with these thyroid disorders. Below is some independent research by Dr Guy Abraham from the Iodine Project on the importance of selenium and, in particular, the glutathione peroxidase enzyme as an essential anti-oxidant in the body that helps to prevent and cure auto-immune thyroiditis problems like Hashimotos and Graves Disease. This paper reveals both the cause and cure for both Hashimotos and Graves Disease:
THE UNDERLYING CAUSE OF AUTOIMMUNE THYROID ILLNESSES: IODINE DEFICIENCY AND ANTIOXIDANT DEFICIENCY
Chapter 7 described the apoptotic (i.e., anticancer) effects of the iodinated form of lactone (delta-iodolactone). Iodolactone is not only important for preventing cancer, its production is also necessary to help regulate the oxidation of iodine. Figure 3 illustrates this regulatory step in the oxidation/organification of iodine.
As previously mentioned, the oxidation of iodide to iodine occurs through the interaction of H2O2 and TPO. Iodine is a necessary product in order to provide the correct molecule in the cell so that organification can occur. If organification does not take place or is blocked, thyroid hormone and iodo-lipids will not be formed. As can be seen from Figure 3, this reaction is controlled by intracellular calcium levels and iodinated lipids delta-iodolactone.
Intracellular calcium stimulates this pathway. On the other hand, delta-iodolactone and other iodinated lipids act as a brake on the system. If there is not enough iodine in the cell to organify and produce adequate amounts of delta-iodolactone, it can set the stage for damage to the thyroid cell and the development of an autoimmune thyroid disorder such as Hashimoto's or Graves' disease.
A Proposed Mechanism For The Development Of Autoimmune Thyroid Disorders
The NADPH oxydase system is found in the mitochondria of our cells. The mitochondria are the energy-producing cells of our body. The mitochondria produce energy (i.e., ATP) through a complex process called oxidative phosphorylation. All medical students (and most physicians) are familiar with oxidative phosphorylation because we have to memorize the many steps responsible for producing ATP. This production of ATP requires many items including: oxygen, magnesium, ADP, and amino acids.
Many people with chronic illnesses, such as fibromyalgia, chronic fatigue syndrome, and autoimmune disorders, complain they have no energy. ATP is the molecule that stores energy for the body. The body is constantly producing and utilizing ATP. Its production is a complex process that is beyond this book. However, there are two cofactors, Vitamins B2 (riboflavin) and B3 (niacin), that are integral to stimulating oxidative phosphorylation and ATP production.
Hydrogen peroxide is a byproduct of oxidative phosphorylation. It is this production of hydrogen peroxide that is so critical to the oxidation process of iodine. Hydrogen peroxide and TPO help to oxidize iodide to form iodine.
If there is a deficiency in iodine, which is common when ingesting the RDA for iodine, there will not be enough substrate (i.e. , iodine) to produce iodinated lipids. As can be seen from Figure 3, the lack of delta-iodolactone and other iodinated lipids results in a loss of the 'brake' in the pathway to oxidize iodide. This may result in a temporarily production of too much hydrogen peroxide. This excess hydrogen peroxide can damage the enzyme TPO.
What Happens If TPO Is Damaged? Autoimmune Thyroid Illness
The body's response to TPO damage is to produce antibodies against TPO or anti-TPO antibodies. A diagnosis of Hashimoto's disease requires the presence of anti-TPO antibodies. As the damage worsens, surrounding proteins can also be damaged such as thyroglobulin. Damaged thyroglobulin will result in the body producing antibodies against thyroglobulin - anti-thyroglobulin antibodies.
In most cases of Hashimoto's disease, there are antibodies to both TPO and thyroglobulin present. Although Graves' disease may also possess these same antibodies, antibody production is not necessary to make the diagnosis of Graves' disease. However, my clinical experience has shown that the treatment for both Hashimoto's and Graves' disease can follow a similar course with similar positive outcomes.
How to Treat Autoimmune Thyroid Disorders
1. Ingest enough iodine in order to provide adequate substrate to iodinate lipids.
2. Take Vitamins B2 and B3 in amounts necessary to stimulate the NADPH system to produce adequate amounts of H2O2.
3. Correct oxidant stress in the thyroid gland and the mitochondria with antioxidants.
4. Ensure adequate magnesium levels.
5. Minimize oxidative stress in the body.
San Fernando, Philippines
I was diagnosed with Hashimoto's in Jan this year. I felt so tired in the morning, couldnt figure out what was wrong. All the classic symptoms. Saw the endo, he put me on levathyroxine 100mcg daily. After 2 weeks I felt 100% better, but I do not want to stay on this med. I was told that Kombucha tea is a cure for Hasi's. I am going to try the gluten free diet along with the kombucha tea. I can not loose weight. Maybe this will help. Let me know what you all think. Bless you!! Mel
Hi, I'm suffering from hashimotos and despite all the tests and treatments, I can get no relief from my symptoms, they are just getting worse. I read that Yersinia enterocolitica could be a cause and it can be treated by kombucha tea. Is this correct and could you suggest other remedies. Thank you so much
re: Hashimoto's autoimmune thyroiditis/hypothyroidism. I have had Hashimoto's hypothyroidism for many years and have been under treatment by my naturopathic physician. Due to symptoms of hyperthyroidism, my doctor performed some tests and this time had no thyroid antibodies! This means that I no longer have Hashimoto's hypothyroidis! The doctor explained that the bacteria Yersinia enterolitica has been linked to the cause of Hashimoto's - apparently it has a similar protein coat to thyroid cells which provokes the immune response. I had not been treated with antibiotics for this. The only thing I have been doing differently is to drink Kombucha tea. I just read on your site that Yersinia enterolitica is sensitive to Kombucha, so it seems logical that the Kombucha was my cure. I drink about 8 ounces per day.
EC: More about http://www.earthclinic.com/remedies/kombucha_tea.html
New Fairfield, Ct
I have Hashimoto's and have for a long time and tried all meds and diets to no avail. They just make me worse even after several attempts.
I have now decided to take Nascent Iodine. I have had a small trial with it a while back and it worked well except my TSH went up too high. Anyway I wish to try it again, but I am not sure how many drops I should take and the other vitamins with it.
I was going to take selenium, magnesium, vitamin D (deficient) B12 Injections (deficient), vitamin C and zinc. Would you be able to point me in the right direction of how much to use of each and if I need others as I have read conflicting things on the net. Oh and one more thing - take it at night or morning?
thank you, Lynda
San Fernando, Philippines
Rhodiola for Hashimoto Disease: Thyroid:
I have been taking Russian-Rhodiola for a week now, 300g in the morning. I'll see my Doctor tomorrow, as I am also under pills for my thyroid, and I would like to replace thyroid chemical pills (Levothyroxine sodium - thyroid hormones) with rhodiola's cure, let's see what he's going to tell me. I feel definitely better, from the first day. I used to be chronically tired, now not anymore.
EC: Read more about Rhodiola here.
I just found out that I have Hashimotos. I read an article about selenium being helpful. Just started taking it.Will give an update in a few months.
Boca Raton, FL
Santa Monica, Ca
re: hashimoto disease: in France we just take thyrosine hormons... but I saw 2 interesting articles, one saying they have a good cure in China, called "shen lu", and another, for which I send you the reference :'http://www.thyroid-info.com/articles/yersinia.htm
I was diagnosed with subclinical hashimoto hypothyroditis since 2012 and was placed on harmone replacement tabs. I had nodules on both sides however one side had gone after being on my meds. Presently I am seeing a small bulge to the front of my neck. I doesn't seems as if my meds is shrinking my bulge. I need help to shrink it. I can produce my blood test results from beginning to present.
I have Hashimoto's disease and a golf ball sized goiter on my neck on the right side of my thyroid. I had an appointment with my endocrinologist two weeks ago. Aside from sending me for a blood test and another sonogram he also said he wants me to have a biopsy. That was when I decided to try some alternatives. I am not allowing them to take out my thyroid and be on medication for the rest of my life when the medication has not helped at all. I found this site and Dr.Batmangheldj's site.
I knew I was dehydrated so I started increasing my water intake to 96 ounces a day. I weigh 180 lbs and Dr. Batmangheldj recommends drinking half of your body weight in water each day. I also started taking extra potassium, magnesium and I take my multi vitamin 3 times a day instead of once because it has iodine in it and the water causes flushing out of your system. The goiter went from golfball size to half of that in less than a week just from the water and increase in supplements. I also do not feel as many bumps as I had on my goiter as I had been feeling when I lay back and stretch my throat.
Also my edema is much better. My hands and face are less swollen and my skin is no longer sticking over my socks a quarter of an inch which they had been for a long time. This past week I have started with the apple cider vinegar and baking soda (2 tbsp ACV and 1/8 tsp of baking soda) twice a day and the goiter has gone down even more. At 52 I thought I was getting arthritis but I guess it was dehydration because almost all aches and pains are gone now.
I live in New York, we have chlorine and fluoride in the water so I am getting a shower filter and the Zero water pitcher (it's supposed to remove fluoride from the water) and maybe my thyroid will improve even more. I will also be trying the Borax to rid my system of fluoride. I'm so glad I found this site. I was feeling kind of hopeless after I left the endos office.
Shirley, New York, Usa
Houston, Tx, Usa
Bozeman, Mt, Us
Zug, Zug, Switzerland
Princeton, New Jersey, Usa
Buenos Aires, Argentina