Table of Contents
- Allergy Shots
- Bentonite Clay to Counteract
- Clavamox and Doxycycline
- Flea/Tick/Heartworm Medications
- Prescription Eye Drops
- Unknown Medication
- Xylazine and Atropine
Last Modified on Jul 06, 2014
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[SIDE EFFECTS] 06/09/2009: Terry from West Palm Beach, FL: "Dog medications for fleas/ticks/heartworm: My daughter has a 15 month old, 88 pound Golden Retriever. Her vet recommended a monthly flea/tick medicine. "Riley" is not the same puppy after this treatment. He is lethargic and sad. I recommended garlic in his food. The vet said absolutely NOT! I've read articles all over the internet, and garlic is given. There are small ticks on him when we walk him. Fortunately they come right off. What can we use to keep fleas/ticks off him that is safe? Why don't vets want garlic used? I cry seeing him after these treatments. So many pets get cancer, and I think it must be related to their food and these toxic medications."Replies
07/13/2010: Gayle from Birnamwood, Wi replies: "I use and have been very happy with a horse fly repellent that I get at a farm store. It is organic and safe to use on cats and dogs over 12 weeks of age. I just spray it on when I notice any bugs starting to bother my pets. Works great for mosquitoes flies, ticks, fleas, gnats and lice."
09/04/2010: Natalie from Greenbelt, Maryland replies: "Gayle, could you please give us the name of this repellent? Thank you!"
09/14/2010: Julie from Coventry, England replies: "Hi, I would recommend sprinkling turmeric and cayenne onto your dog's food. It appears the ticks and fleas don't like the smell. My dog spends alot of time in The New Forest and the area is rife with ticks. He has not had one. Forget what the vet says, these toxic chemicals he is selling you can cause brain problems as well as affecting the nervous system. GO NATURAL."
11/03/2010: Sp from Lavergne, Tn replies: "Hi, In regard to the garlic. How much garlic can I give my dogs? Thank you."
07/07/2013: Mary from Regina, Saskatchewan, Canada replies: "An idea for mosquitoes that dogs can safely be given black walnut hull (powdered), I use it myself. It stops them from biting among its other positive qualities."
[WARNING!] 02/25/2011: Julee Johnson from Medina, Ohio, Usa: "I read on here that a women's Border Collie had seizures when her dog was on Heart Guard. I do not keep my Border Collie mix on Heart Guard year round. She has had three seizures that I have witnessed over the years. I went through her records and she was on Heart Guard at the time of all three seizures. I don't think I'll put her back on it and I'll be curious to see if she has anymore."Replies
[WARNING!] 05/05/2011: Doug from San Antonio, Texas replies: "Ivomectrin should not be used on Border Collies it absolutely causes siezures. We chose Advantage Multi based on research and advice from several other Border Collie owners. Our two year old Border Collie has had no problems with Advantage Multi."
[SIDE EFFECTS] 03/19/2012: Michael from Chilliwack, B.c. Canada replies: "Ivermectin destroyed maggie's nerves... (my first border collie)...."
[SIDE EFFECTS] 01/21/2009: Lisa from Lilburn, GA: "Side Effects to Pet's Medication: The day after giving my 43 lb Shepherd mix her Heartguard heartworm medication containing ivermectin, her face and upper lip swelled up. She looked as if she had been stung by a bee, but it's Winter here and she had no sign of insect bites. There are no other possible explanations. The vet thoroughly checked her out and couldn't find the source of the problem. He did not suggest an allergic reaction to Ivermectin. However, after researching the drug I found out that facial swelling can be a side effect. Benadryl has helped a little, and we placed her on antibiotics just in case there is a local infection."Replies
[SIDE EFFECTS] 01/29/2009: Teresa from Mccomb, Mississippi replies: "I have 11 beautiful dogs. Needless to say I am an animal lover and live well below poverty level, but I try very hard to take care of my dogs. I have been giving my dogs ad diluted mixture of Ivermectin for years for all worms, including heart worms.
The mixture was given to me from a kennel in Louisiana. BEWARE, Ivermectin is very strong in small doses and is very hard to give to a small dog, but at this time my dogs are doing well on it and it IS NOT recommended for COLLIE BREEDS.
FOR ANOTHER NOTE.... my full blooded Siberian Husky had a toxic reaction to it as well. She started walking like she was drunk and weak, had shallow breathing and at one point she quit breathing. I researched and found that this was a definite side effect from Ivermectin. I took her off it immediately and put her back on a monthly pill from the vet. The pill still has Ivermectin, it says so on the packet, but the dosage is so miniscule compared to my personal mixture. I do believe however in my personal opinion only, that her hyperactivity had some cause in her having a reaction. My other 10 dogs are doing well and haven't had any side effects and none have never tested positive for worms of any kind."
[WARNING!] 10/25/2010: Karen from Idaho Falls, Id replies: "My sister-in-law raises show shelties and has done so for at least 20 years. She informed me that it is a known fact that shepherd breed dogs are highly allergic to ivermectin- it should NEVER be prescribed for herding dogs as it is known to be fatal to them. That vet should never have given it to a shepherd mix."
[WARNING!] 04/29/2011: Itsytexan from Houston, Tx replies: "The rule is "White Feet Don't Treat", which I have recently learned the hard way. My vet gave my dog heartworm preventative with Ivermectin in it and she almost died. I have since learned that some dogs, often the ones with tan or brown bodies and white feet (hence the rule) have a gene mutation that makes then sensitive to Ivermectin. It basically goes straight to their brain. It's ugly. The vet never should have given this dog, that was a stray with 4 white paws and looks like an aussie/lab mix (aussies, collies, and a few other breeds are more likely to have the sensitivity). And when she saw that my dog could barely walk, she should have known what was happening. Please spread the word about this."
[WARNING!] 08/28/2011: Cheryl from Fort Worth, Texas replies: "I have used Iverectin for over 20 years from Mastiffs to Mini Schnauzers, Am Staffs, Jack Russels.. One of my Am Staffs is solid white and she has done great on it, I have never had a problem with it at all, but I was warned years ago, NEVER give to them while they are hot.. So I dose mine early morning.. That may be part of the problem with some of the effects some have seen using it."
[SIDE EFFECTS] 02/12/2012: Cinmorin from Edmundston, Nb, Canada replies: "We gave my Aussie 105mg of pyrantel (which seems to contains Ivermectin) two weeks ago and she had two seizures in the next 8 days. We were devasted and didn't know what to think. I asked 3 vets about it and only one seemed to believe it may not necessarily be epilepsy... She has been seizure free for 4 days now, but I'm still anxious about it... Is there something we can do or a mediation that could help her recover? I'm scared it could worsen..."
[WARNING!] 03/03/2012: Jilbert57 from Brinnon, Wa, Usa replies: "I have a 5 year old aussie/heeler who I give Interceptor to monthly for heartworm prevention. I was told by two different vets not to use a medicine with Ivermectin in it as the herding breeds are subject to seizures from it."
[SIDE EFFECTS] 12/19/2012: Roxane from Rocklin, California: "My six-year old Silky-Yorkie mix was put on Ketoconazole for a fungal infection in his ears. A few days later I woke up to vomit all over the house! Took him back to vet, where he spent the day having tests, including an ultra sound for his organs.
Here is what they found: Inflamed, swollen liver, pancreatitis, extremely high blood glucose levels. And other, more minor things. Now he must have insulin injections twice a day for diabetes caused by the pancreatitis. He was overweight but in good health otherwise. He is tolerating the insulin well, but I was beside myself the day he stayed in the pet hospital, as they told me I had a very, very sick dog. His name is Harry.
I thank God he made it through, but am so sorry I ever gave him that Ketoconazole. Antifungals are rather dangerous for humans, so what was I thinking when I gave it to my dog? I have good vets and don't blame them, although I wish they had told me about the liver side effects. I think that if a drug can harm the liver, it can surely harm the pancreas. Could not be a rare coincidence, come on! And now he is a diabetic for the rest of his life. It's quite a chore making sure he gets his shots twice a day, but my Harry is worth it! You all know what I mean! -- Roxane"
[SIDE EFFECTS] 07/16/2013: Mskuhl from E Patchogue, NY: "My dog Bailey just died today. He was on Ketoconazole, and developed pancreatitis and diabetes. We took him back to the Vet to put him on fluids and insulin. He was at the Vet overnight, when they called in the morning to say he develope a fever of 109 and to come in because he would die soon. He was only 9yrs old and was a great companion. We should put a class action suit against the drug company that makes Ketconazole."Replies
07/17/2013: Laws from Maywest, Fl replies: "Find a lawyer that could show that ketoconazole was the cause of death and you could have a good case."
[DEATH REPORTED] 07/27/2012: Bruce from Cumming, Ga: "My 4 yr old 72 lb Golden Retriever Scout died today. I believe his death may have been caused by ketoconazole. My vet prescribed ketoconazole 300 mg twice a day for a yeast infection in his ears. Scout also received his annual vaccinations for rabies and bordetella the same day the prescription began.
Scout died on the 11th day after beginning this treatment. The only symptom he exhibited over this time period was a decrease in energy and on his last day, a lack of appetite.
I will never allow my dogs to take this drug in the future. I would appreciate any information about ketoconazole and others experiences with this drug."Replies
07/31/2012: Poes4me from Belle Center, Oh replies: "Bruce, from Cumming, GA, I'm sorry to hear about your friend Scout. Because I've heard some good things about Ketoconazole I didn't hesitate to give it to my yeasty, 12-yr-old peke when my vet prescribed it. However, by the 3rd day of taking it my peke started showing signs of ataxia, and by day 5 he could barely lift his head, and could barely walk, so I discontinued the med. I don't know if the combo of it along with his phenobarbital and potassium bromide (for his seizures) caused the toxicity, but Ketoconazole will never be given to my boy again."
08/30/2012: Daveyo from Nakhon Sawan, Thailand replies: "Sorry to read about the death of your dog. 300mg of that stuff is definitely a killer. A huge overdose. Sue the VET or find another VET or report that VET to the VETERINARY BOARD and have its license be revoked. You have some options to think about.
My God, seems the VETS are getting worse.
[DEATH REPORTED] 08/10/2008: Guenady from Nice, France: "For your accumulated information on adverse reactions to drugs, two of my dogs were prescribed ketoconazole for a yeast skin infection. One survived the treatment, the other died during treatment. Other than the skin infection (which was not life threatening), he had no health issues. I was not told before treatment that this medication is hepatotoxic and that it can kill, that it has been established by the manufacturer that there is a 1:10,000 risk of allergic reaction (with underreporting recognized). The vet was not aware (!) of the symptoms of allergic reaction, so when I reported them she did not stop the treatment (dark urine, extreme fatigue, skin turning black and peeling...). When I finally stopped the treatment myself, because my dog was just getting sicker and sicker (after 13 1/2 doses administered out of 30 prescribed) it was already too late. 4 days later he came down with hepititis and 34 days after starting the treatment he died (with bloody vomitting and bloody diahrrea). Although I reported all this, despite my distress) nothing was taken into consideration, everything was dismissed as being a coincidence, and I was given the classic excuse 'your dog was already sick and would have died anyway.' This is an outright lie, of course, and contradicts all the medical file of my dog. But try to get an adverse reaction taken into consideration when the 'authorities' don't want to take it into consideration! Of course there is underreporting! Normally I never give vet medicines to my animals, only homeopathy, but at the time I had no alternative therapy, as skin yeast infection is very difficult to treat. I have since gotten my second dog almost out of her condition, using probiotics and herb Robert and direct applications of hydrogen peroxide on the worst affected areas. My opinion of vets and the authorities that 'oversee' them, has descended to about 0. Would like to know if others have had bad experiences with ketoconazole."Replies
[SIDE EFFECTS] 08/12/2008: Cindy from Torrance, California replies: "I had a similar problem with Ketoconazole as my Shar Pei had a terrible case of yeast. I stopped the medication after his underbelly started spotting black. After scouring the internet I found the website nzymes.com. It took over 1 year to completely clear up the yeast using their protocol and only feeding him a protein diet (I still cook chicken and spinach for him). I recommend anyone who has a yeast problem with with pet to start them on this protocol."
[DEATH REPORTED] 10/03/2008: Jean from Desert Hills., Arizona replies: "I would like all pet owners to not give their dogs Ketoconazole for Yeast or Valley Fever. Against my best judgment I gave this to our dog for Valley Fever and he died 3 months later from a failed liver. This is one of the side effects. It is much better to go Natural and stick with this so your dog will have a better life. And by the way they have a cure in Tucson, Arizona at the University of Arizona, but this is another drug and would have to be checked out for side effects. Many states have Valley Fever now. The states are California, Nevada, New Mexico, Texas, Arizona, and Utah. This problem in in the dirt. Something needs to be done. This affects humans and animals and etc.
Please beware of what I am saying for the sake of your pet!!!"
[SIDE EFFECTS] 11/15/2008: Pamela from Austin, Texas replies: "My 8 year old standard poodle was prescribed ketoconazole to suppress a chronic yeast outbreak in his ears. His liver would not tolerate it. I pilled him once. He vomited bile. That was the end of that."
[SIDE EFFECTS] 02/07/2010: Dana L. from Darlington, Sc replies: "My pekingese mix was prescribed Ketoconozole three days ago but after her third dose today (100 mgs 2x daily) I think I'm going to stop giving it to her. She has developed a nagging cough, which she has NEVER had before since she started taking this medicine. I'm worried that the long-term side effects will be much worse than this cough we're experiencing. I don't know what I'll do about the yeast infection in her ears but we'll just have to find something else!"
11/25/2010: Lulu from England, Uk replies: "Just wondering if Ketoconazole Shampoo has the same effects as the medicine? I use the shampoo for treatment of scalp psoriosis and works well. After reading the items about Ketoconazole Im just not sure if I should use it on my dog? any thoughts would be much appreciated : )"
[DEATH REPORTED] 06/20/2011: Steph from Kennedale, Tx replies: "An australian shepherd or border collie mix puppy we had taken had some kind of rash so we thought after a month of it not going away after using different shampoos we should take it to the vet. He was treated for ringworm. The vet had prescribed ketoconazole and after 5 days of giving the half tab every 12 hours we noticed he stopped eating. We were told to stop giving the medicine and to try giving boiled chicken and rice. The pup became very weak and fatigued and would not eat and just lay there. Deciding not to take him back to the vet who had prescribed this treatment which was made him worse than what he was originally, we let the dog peacefully go.
I would really think twice before giving dogs medicines and found out that most cases of ringworm can disappear on their own. I should have stuck with mother nature instead of trusting a licensed professional to assist with this matter of nature."
08/22/2011: Julie from Coventry, England replies: "ALL OWNERS OF COLLIE & SHEPHERD DOGS & CROSSES OF THESE BEWARE, THEY HAVE CARRY MDR1 GENE WHICH MEANS MULTI DRUG RESISTANT 1 GENE AND SHOULD NOT RECEIVE MEDICINES WITH IVERMECTIN /AVERMECTIN IN (FLEA TREATMENTS) NOR ERITHROMYCIN ANTIBIOTIC OR IMODIUM THESE DRUGS CAN BE FATAL. TELL ANYONE YOU KNOW WITH THESE BREEDS. PLEASE."
12/27/2011: Jeffersonhi from Mililani, Hi replies: "Our 15 year old New Zealand Light Golden Retriever was prescribed Ketaconazole on 12/10/2011 by our vet, who did a complete work-up on her since she hasn't been in to see the vet in two years. We were there just for a check-up which they "required" in order to refill our Rymadil prescription for her achy joints. They did a blood test, fecal sample exam, the works - and kept her in the small kennel cage all day long... Then charged us $480 for it all. We were gratified to hear from the vet that she's a strong dog for her age, and had a clear result from her blood and stool sample test.
We dutifully gave her the Ketaconazole twice a day... But stopped after she refused to eat anything. We went online and discovered this (and many other) threads documenting the terrible and awful reaction to Ketaconazole... And are worried sick. We are giving her Pedialite to get fluids into her (she licks the bowl clean), but don't want to give her food yet... Since she was vomiting everything we gave her earlier. It's been 12 hours since she last ate. We have no alternative but to take her back to our vet (who has otherwise been a good friend and shown kindness in every respect to our dog and us). We will be sure to print out this thread for his enlightenment on Ketaconazole."
01/08/2012: Cheryl from Stockton, Ca replies: "To the December 2011 poster - how is your dog doing?"
01/14/2012: Carly from Raleigh, Nc replies: "My 10 year old Jack Russell began allergic reactions to, what we thought and were told by vets, flea bites. The itching and chewing to the point of seeping sores has driven him (and us) crazy for nearly 6 years. We spent ridiculous money on one remedy on top of another, injections, steroids... You name it. We became a stressed out, worn out, broke and vet-leary bunch embarrassed to be seen in public with our patchy smelly dog that appeared to be neglected and abused. Our dog was miserable and we were clinically depressed of the whole issue... And (can't believe I'm saying this) considered other options to relieve his suffering, and ours.
Then came the day when I was faced with what I thought were earmites and a severe ear infection. This was a first for my dog and I was confused because it didn't LOOK like earmites but was red, crusty and he was scratching it raw.
Finally, at my wits end, I was reading a homeopathic site and the article mentioned the smelly, itchy stench of a yeast infection in dogs. Frankly, never having had one, I was under the impression this was only a human and female ailment. WRONG! I began treating him immediately for a yeast infection. I started him on Blue Buffalo food (duck) and half a tab of acidophilus and filtered water. I rinsed out his ears with an earwash and bathed him in Nazirol (ketoconazole) shampoo every 2 days. I currently use only hydrosol for fleas and ticks.
My dog, in just over a week, has become a different animal. He is the dog we originally brought home. His eyes are clear and alert, he is energetic and keen and he sleeps like a rock, no scratching, no anxiety and we are sleeping disturbance free.
I am posting this because I can't even imagine giving ketoconazole orally. I am deeply disturbed that for so long and from so many of what were touted to be the best veterinarians in our area, not one of them suggested that Yeast might be the problem. I have decided to seek out a holistic Veterinarian because I no longer trust the expensive drug-pushing establishment.
Nutrition is a best weapon for many ailments. While I am in no way suggesting medicine has no place in treating animals, I will say that owners should be cautious."
[DEATH REPORTED] 06/18/2013: Heather from Fayetteville, Ga: "My cat Limpy was given one Metacam injection after having a few bad teeth pulled. She came home and was eating and feeling good but with in a week she stopped eating. The vets found Fuild all in her chest but no signs of cancer. Sadly she passed a few days later. I had no idea there were so many reports about the side effects of Metacam. There is a web site called Metacam kills.com. I will always believe this drug killed my cat. The vets are so misguided by the drug companies and seem to be more interested in padding their wallets. I lost the best cat I have ever known because of the vets and this drug Metacam."
[SIDE EFFECTS] 04/19/2013: Palhuc from Edmonton, Alberta, Canada: "I took my 5.5 month old ragdoll kitten for spaying this week. After 2 of the 4 doses of metacam given to her for pain I noticed she was so hyper, jumping up walls and nonstop climbing. She also appeared to be watching the ceiling and I could not get her attention (possibly hallucinating). She responded very well after surgery, ate , drank and went to bathroom almost immediately after coming home from surgery.She did not appear to be in pain but I did not want to take a chance so that is why I gave her the pain meds. Today did not give pain meds but she is very calm and not hyper like on metacam. I believe this was not a good med for her. I will continue to monitor for any changes in behavior and changes."Replies
05/04/2013: Andrea from Hobart, Tasmania, Australia replies: "My cat Sam-Panda has a serious heart condition, and has lately developed a throat irritation. He was prescribed Metacam for the irritation, but just as I was about to give him his first dose I read that it is contra-indicated in animals with cardiac disease. Reading about other animals experiences with this drug, I have no doubt my precious boy would be dead now if I had followed the ve'ts careless advice."
10/25/2011: The Doob from Truro, Cornwall, England: "Took my healthy, normal old english sheepdog 6yrs old to vet with small scab. Removed it, gave metacam jab after op. Swelling at op site few days later, gave more metacam to reduce swelling. Then started with side effects of metacam, ie bloody stools/bloody vomit. 3 day stay in vets with gastric ulcer. They said he was fit to collect him, bring home.. But I could see he was sick, fluids on abdomen, rushed him to another vet's, referral centre. Severe advanced peritonitis, ulcer had perforated. Major op. Complication after complication, because the perforation was not detected/treated early. Feeding tubes.. 2 failed oesophagus tubes, abdomen reopened to place gastric tube, that worked. Came home, food and meds through tube for three weeks..liver/pancreas now recovered. After three months, all tests now normal. £12,000!! Couple weeks ago one of my other dog had a lesion.. Wet eczema, new vet wanted to stick him with steroids, NO WAY!"Replies
[NAY] 03/16/2012: Anneg from Portsmouth, Hampshire, Uk replies: "My 16 month old Portuguese Water Dog Dylan was castrated on 12th March and sent home with Metacam. I dosed him with 24ml (dog weight 24 kgs) as directed on 13th and that night, all night, he had horrible yellow explosive diarrhea - I thought it was a reaction to the op and Metacam was supposed to make it better so give him another dose on morning of 14th - by the afternoon he was lethargic and couldn't/wouldn't eat so phoned the vet who told me to take him off the Metacam - he had diarrhea all that day and night and very little to eat. Yesterday he just lay around and had nothing to eat but we did manage to get some water in to him - last night I was only up 3 times with him and today 16th he has not had to 'go' since about 8 hours ago and has eaten a little chicken so seems to be on the mend.
Having now researched this drug on the internet I would not touch it again with a barge pole!!"
[WARNING!] 12/20/2010: Godsgal from Santa Clarita, Ca: "My late Bichon Frise was prescribed Metacam (meloxicam) 1. 5mg oral suspension for arthritis. He did not show any symptoms of arthritic pain and was a bouncy, youthful little guy until he was given this medication. After only one dose, he became disoriented, started walking in circles and kept "crying". I immediately took him off these meds and did a search on line about this medication. There were so many side affects that I called the vet to discuss this. He refused to take my call. My little guy lived another 2 years but his quality of life was gone after just 1 dose! Please beware of this drug!"
[DEATH REPORTED] 06/07/2009: Norma from North Vancouver, BC: "I had a 11 year old Rough collie with very bad arthritis. I had had him on Recovery for a year and a half but he was getting worse with age. I decided to try Metacam even though I had been very nervous about it. Within 10 days he became very ill - and I rushed him to the Vet. His heart rate was a way up and his gums were very pale. He ended up in the Critical Care unit and was diagnosed with ulcers and he had vomited and ingested and had pneumonia and partial bloat which they had to wait out because of his condition.
My Collie came home with many meds and he did recover. I had him on something to coat his stomach but within 2 months he had bloat again and had to be put down. I will never again put a dog on Metacam. I do not recall the measurement for Metacam but it was whatever was recommended for his weight."
[DEATH REPORTED] Dalia from Winchester, United Kingdom: "Re: Metcam (allergic reaction). I had Teddy, a 2 year old pekingese who put his back out. The vet injected him with Metacam and within hours he had breathing problems and the next morning he died. The vet admitted the death was caused by an allergic reaction to the Metacam and he did what he could to counter balance the reaction but to no avail. Has anyone else had this problem?"
[SIDE EFFECTS] 06/06/2009: Ingrid from Geneva, Ohio: "My dog was on metronidazole last year for colitis. The vet put her on two meds. I don't remember the other off hand but another vet was surprised she was put on both at the same time. She also was given a higher dose than my other dog who is a bit bigger than her. She became incontinent. After searching the internet I found this was a side effect. It took a while but it finally passed. I believe it was the medicine and it had to completely leave her system for her to get back to normal."Replies
[WARNING!] 03/01/2011: Casperc from Casper, Wy replies: "My 5 yr. Old OES dog was prescribed 1500mg of metronidazole 2 times a day for 10 days initially because of vomiting and diarrhea. With the first vet visit a blood workup was done with good results, just a little dehydration. The second vet visit was 7 days later because the vomiting was still happening (stools were a bit better). They did x-rays on the second vet visit that revealed thickened intestines (maybe a foreign body present also???) and he was prescribed an additional 10 days of 1500 mg 2 times a day of metronidazole.
I came home last night (17 days into taking meds) to a dog having a seisure and not being able to get up afterwards. When I tried to move him he had another seisure and again was unable to stand afterwards. The vet came to the house and as they tried to move him he had another seisure. They administered valium to calm him. After some time he was able to get up and was wobbly. They kept him overnight and apparently he had more seisures this morning. They are trying to keep him sedated and hydrate him and will keep him for another day at least. We're suspecting the Metronidazole."
[WARNING!] 04/10/2012: Planetheart from Los Angeles, Ca replies: "Holy crap I was just reading that your dog was put on 1500 mg of metranidazole. No wonder your dog was having seizures. That's way tooooo much of a dosage. Even if your dog was 100 pounds, the dosage should have not been more than 500 mgs twice a day. Someone really screwed up big time. We rescue special needs dogs and many of them are actually on metranidazole, never had an issue and if a dog needs to stay on it long term, after a week or so they usually keep them on it once a day, not twice a day. A 5 pound dog, only gets 25mgs twice a day. I'm so sorry this happened to your dog....."
[SIDE EFFECTS] 11/29/2008: Christina from Ashburn, Va: "our dog was was put on a long term dose of metronidazole for irritable bowel syndrome a few months ago. unfortunately the medicine caused severe neurological issues in our 12 year old lab/husky. shortly after taking his morning dose one day, he wasn't able to walk straight and lost all control of his limbs. he's mostly recovered, but i think he has had some side effects from this medicine. he was experiencing some arthritis issues prior to this but it's gone down hill rapidly since (the neurological episode occurred this past june, and now our pup can't nearly walk as far as before, despite herbal treatments and acupuncture). i think the use of a long term dose of metronidazole should really be studied further."Replies
07/28/2010: Crysgrits from Charlotte, Nc replies: "I had an incredibly similar experience with the metronidazole, although our dosage was not long-term, it was a typical 10 day dosage. My 7 year old terrier mix was put on metronidazole as a precaution because she was sick and they were using it as an antibiotic. After about 2 days of being on the drug, she was unable to walk straight, a few hours later, she was unable to operate her hind legs. The vet we were using kept her for the day, flushed her system, put her on iv's, etc. However, I would not let them keep her overnight, as they did not have anybody there overnight. I picked her up and intended on keeping her for the evening. A few hours later, I couldn't take it. It was clear that she was completely unaware that I was sitting right beside her, and her eyes began shaking (shifting right to left) uncontrollably. I had to take her to an emergency vet (different vet), and he warned me that this is a rare side effect, but known, and can even happen in humans as well as dogs. He told me it essentially attacked her brain. Luckily she turned out to be OK, after 2 days in the hospital hooked up to fluids to flush her system of the drug, but apparently most dogs with the reaction are not as lucky. None of my dogs will ever be given this drug again."
[WARNING!] 03/05/2011: Lblibris from Slc, Utah replies: "My 15 year old cocker developed nuerotoxicity to this drug and unfornately passed away within one of week of taking it. Please view this website that tells about our experience and more information, including where to report adverse reactions to medications. sites.google.com/site/bewareofmetronidazole"