Joint pain, Colds Flu, General Immune system weakness I take 4+oz and 3 620 mg capsules on an empty stomach and wait 30 minutes before eating every day and have done for the past 7 years. A non-citrus fruit juice or water can be drunk before the 30 minutes is up. I noticed after starting Noni that I stopped having the onslaught of colds and flu each year. Once a year only, I would get a very mild version of whatever bug was going around and usually recovered quickly. My dentist even commented after examining my teeth, "You must have a really strong immune system!"He saw that a situation we had forgotten about for 18 months had not deteriorated one bit during that time. A 60+ contractor friend takes it every day so he can stay active and live without knee-joint pain after suffering with it throughout his 50's. My toddler grandson suffered when a cold turned into pneumonia and since we have been giving him 1 tsp a day and waiting 30 minutes (VERY IMPORTANT), he has not had any further complications from a cold. The original Polynesians so revered the healing qualities of NONI that they carried it with them on their 3,000 mile voyage to Hawaii. Hawaiian noni juice is generally considered to be the strongest. Big Island Noni...highly recommended.Cheaper if you order directly from them. If you can get past the smell (Remember...the stronger it smells, the stronger its effect!)as I do when I hold my nose and drink it, the taste is actually rather sweet. When I first started taking it, I noticed more energy and a lessened desire to smoke.