Melatonin Lotion
Health Benefits

Melatonin Lotion for Pain Relief: Recipe + Success Stories

The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.
Q&A
Posted by lynn (pa) on 08/06/2024 7 posts

Hi Art,

After I used high dose of melatonin for sleep problem for a while, I got joint pain on knees. I thought melatonin supposed to make pain better not cause pain. Then I searched internet, people review said melatonin cause them big deal of pain. website address is "https://www.fightaging.org/archives/2008/10/melantonin-and-hidden-complexity/" people were talking about serious joint pain all over their body caused by melatonin.

My question is if oral melatonin taking make my joint pain, what about melatonin lotion? can I still use melatonin lotion even I cannot take melatonin orally.

Lynn

Q&A
Posted by lynn (pa) on 08/06/2024 7 posts

Thanks for answer my question. other question is "since you use very big doses melatonin, do you have any join pain caused by Melatonin?


Q&A
Posted by lynn (pa) on 08/07/2024 7 posts

Hi Art,

Thank you answered my question. I am just wondering that you use high dose of melatonin for a while, did you ever have jointing pain after you take melatonin? I am ask this because I am still think maybe my joint pain caused not by melatonin, because before I do not have any problem for any my joints, after I changed melatonin pills to melatonin gummies. is something in gummies made my joint pain? I stoped melatonin gummies from Saturday night, today is Tuesday noon, I feel a little bit better on my knee pain. I hope after 2 weeks I will be normal.


Where to Buy: Canada
Posted by Guzin (Vancouver BC Canada) on 05/01/2024

Hello Earth Clinic, I am not able to find any melatonin powder. Just wondering if anyone knows where to order it from? Regards

Q&A
Posted by Mary P (Utica NY) on 04/18/2024

Hi Art! I have melatonin caps… can I open them and prepare this recipe? We only need a 1/4 teaspoon.


Q&A
Posted by Art (California) on 04/18/2024 2684 posts

Hi Mary P,

So the one quarter teaspoon is all melatonin and it equals approximately 750 mg of melatonin. You have to consider that melatonin capsules contain a significant amount of fillers so it will take much more than a 1/4 teaspoon of these capsules to get to 750 mg of actual melatonin. It will take the amount of capsules that it takes to equal 750 mg of melatonin. So if you have 10 mg capsules, it will take approximately 75 of these 10 mg capsules to get to that 750 mg area and you can see that 75 capsules is going to be way more than a quarter teaspoon.

There will also be a problem with the solubility of the fillers which may not dissolve in gin and will make the lotion feel gritty. Another potential problem is that some of the fillers may dissolve in the gin, but that may preclude the melatonin from fully dissolving in the gin in which case you will essentially have a diluted mix which may not be effective at all.

I recommended melatonin powder because that is what my friends used and found effective. Since those first three friends reported their results, many other friends and acquaintances have also reported significant benefits from using that same mix.

I highly recommend following what they did in order to make an effective melatonin lotion.

A few friends have reported that mixing all three ingredients together at once by mistake, produced a lotion that gave little to no pain relief. You have to thoroughly dissolve the melatonin in the gin first and then add the lotion to that mix, otherwise the lotion will offer little to no benefit.

Art


Psoriasis and Hyperpigmentation
Posted by Art (CA) on 04/03/2024 2684 posts
★★★★★

This new study suggests melatonin lotion is effective in treating mild to moderate psoriasis:

https://onlinelibrary.wiley.com/doi/10.1111/srt.13689

Here is a relevant study quote :

' Also a significant decrease of 35% (mean (SD) of 2.67 (0.98) to 1.74 (1.12)) and 51% (mean (SD) of 2.67 (0.98) to 1.31 (1.13)) in PASI score, and 40% (mean (SD) of 5.00 (1.58) to 3.00 (1.76))and 61% (mean (SD) of 5.00 (1.58) to 1.92 (1.71)) in DSS score on days 30 and 60 with melatonin cream, 5% w/w (P < 0.001) compared with baseline were observed, respectively. In each of the melatonin or rosuvastatin groups, DLQI improved significantly on days 30 (P < 0.0001) and 60 (P < 0.001) while the changes in the control group were not significant. '

I had already reported that it was synergistic with certain psoriasis medications in the list of 40 items (#34) and helped eczema of the scalp (#6) while other studies suggest it can be useful for atopic dermatitis and other skin conditions, as discussed here :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9967801/

Here is a relevant quote :

' It has cytoprotective, immunomodulatory, and anti-apoptotic effects. Melatonin is also one of the most powerful natural antioxidants, directly acting on free radicals and the intracellular antioxidant enzyme system. Furthermore, it participates in antitumor activity, hypopigmentation processes in hyperpigmentary disorders, anti-inflammatory, and immunomodulating activity in inflammatory dermatoses, maintaining the integrity of the epidermal barrier and thermoregulation of the body. Due predominantly to its positive influence on sleep, melatonin can be used in the treatment of sleep disturbances for those with chronic allergic diseases accompanied by intensive itching (such as atopic dermatitis and chronic spontaneous urticaria). According to the literature data, there are also many proven uses for melatonin in photoprotection and skin aging (due to melatonin's antioxidant effects and role in preventing damage due to DNA repair mechanisms), hyperpigmentary disorders (e.g., melasma) and scalp diseases (such as androgenic alopecia and telogen effluvium). '

It seems that we are just scratching the surface of what melatonin lotion can do!

Art


Alleviates Nerve and Muscular Issues
Posted by D Pole (Qld) on 09/24/2025

Does anyone know how I can purchase Melatonin Powder in Australia?


Back Pain Relief
Posted by Marshagail (United States) on 08/04/2025
★★★★★

What about using hexane free Castor oil?


Melatonin Lotion Feedback
Posted by Marlena (Oregon, USA) on 11/14/2023

Thank you for writing out your questions to Art. My questions are similar. Cetaphil lotion is not too bad, but not good either. I agree with your coconut oil suggestion as long as it's organic. I wonder why Art specifically adds gin as an ingredient. Higher quality gins do have natural botanicals in their formulas.


Melatonin Lotion Feedback
Posted by Marshagail (United States) on 08/04/2025

I'm probably being real dense here but I'm having trouble with figuring out how much Melatonin powder to add as the Bulk Supplements come in varying milligrams (2mg, 3mg, 5mg, 10,20 etc). I want to make this as close to what your friends used. Can you please help me as I don't know which milligram powder to purchase & am definitely not mathematically inclined!


Melatonin Lotion Feedback
Posted by Leesa (Arkansas) on 11/16/2023

I was wondering the same thing.


Where to Buy
Posted by Hy (Florida) on 11/14/2023

My name is Hyacinth. I receive Earth Clinic emails. I particularly want to find out about the email sent today regarding Topical Melatonin Powder and the Cetaphil Moisturing Lotion to make to recipe for topical pains in lower back, neck and shoulder.

I called a Homeopathic Pharmacy but they did not have it, as I bought two other items related to Earth Clinic's email. I am really interested to know where the Pure Melatonin Powder and the Cetaphil Moisurizing Lotion could be bought as there was no note of this on the link. Thanks.

Melatonin Lotion Feedback
Posted by Jan (Ga, Usa) on 11/14/2023

Melatonin Lotion plus oral melatonin?

Question for Art please. I usually take 2,500 mcg capsules of Melatonin at night for help sleeping. Do you have any suggestions or advice for using some Melatonin Lotion for neck and shoulder aches?

Thank you. I appreciate your information.

Melatonin Lotion Feedback
Posted by Rusty (Lewistown, mt) on 11/14/2023

I take melatonin tablets-10 mg, for a sleep disorder along with numbness & pain in my back, feet, and hands(carpal tunnel) Would the tabs be just as helpful as your mixture?

Thank you (looking forward to a sucessfull outcome)

Sincerely

Richard


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