I used both Apple Cider Vinegar and MSM to cure a "trigger finger". ' A big knot appeared on the inside of my thumb joint. It was EXTREMELY painful. I couldn't write or do anything with that hand. I didn't realize how important my thumb was. The dr. gave me a cortisone shot in it (ouch) and said if that didn't help, he would have to do surgery and cut the tendons in my thumb to try and relieve the pain. The cortisone shot didn't help. I received a magazine in the mail shortly after this talking about MSM. I decided I had nothing to lose by trying it. After a few weeks of using MSM, ALL the pain went away. (This all happened about 5 years ago). The knot was still there even though the pain was gone (it was a very obvious knot). I then started taking apple cider vinegar tablets and WOW, the knot disappeared!! It is still gone and so is the pain.