Skunk spray is oil-based. This is the first thing that every dog's person should know. Since it's oil-based, you need a product that will cut the oil. The rescue workers who save the sea animals when there's been an oil spill use Dawn dishwashing detergent. I used to be a dog groomer and can tell you unequivocally that this one does the trick! Make sure you have a "bath puff" (one of those net balls people use in their baths) on hand... Get your dog all wet. Pour a little bit of Dawn onto the bath puff and work up a good lather. Rub that puff all over your dog's body, making certain you get the smelliest spots, and let your dog stand there for 1-5 minutes, depending on how well-mannered your dog is. :) Rinse off, sniff, and repeat if necessary. When you do around their eyes, be careful not to get too close, as this will sting.