I made the pyoderma treatment just as it said to after trying every shampoo and treatment for our puppy's mange for the past 6 wks which has resulted in pyoderma. I just put her first application on no more than 1-2 hrs ago and she has scratched her head raw to the point of bleeding now. She looks absolutely horrible but physically she doesnt seem to be affected by the mange/pyoderma, nor did she scratch at it. It's obviously made her very itchy, as a result scratching where I applied the paste until it bled... Is this normal? Anyone elses dog have the same reaction?