I'm in Australia so we might have differing vaccines from the US but on 1 October 2013 my pure English Staffordshire Bull Terrier, Star, born 13 July 2013 had her first C5 vaccination, brand CANVAC, vaccinations for Living Canine Distemper virus, Adenovirus type 2 and Parvovirus type 2, Living Canine Parainfluenza Virus and Bordetella bronchiseptica.
Initially afterwards she was fine, and fell asleep. About five hours later she woke up yelping, like she was in pain and I could not touch her anywhere without her yelping. She could barely stand up, had no energy, when she tried to walk it was very, very slowly with limbs shaking. She was shaking very badly. We rang the vet and he tried to tell us she must have eaten some insecticide in the backyard (we had none). She ended up spending the evening/night on my lap mostly sleeping, yelping anytime I moved or she woke up. She was fine the next day.
When she was due for her next booster she was given an anti-histamine injection first and this helped, she was just sleepy after the vaccination, none of the other symptoms were present. Funnily enough the vet tried to pretend it must have been another vet with another brand until I showed him the vaccination certificate.
She had her C3 vaccination (Companion C3) at the breeders vet on 26 August 2013 with no complications.