Berberine CaelumCore

CaelumCore Liposomal Berberine: Lab Test Results and Safety Findings

| Modified on Nov 27, 2025
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Berberine Supplements

Berberine has exploded in popularity for blood sugar, weight, and metabolic support. As interest has grown, so has the number of new brands selling berberine on Amazon — many with very high milligram claims and dramatic promises.

One of these brands is CaelumCore Liposomal Berberine HCL 1500 mg, which is sold widely on Amazon and other marketplaces but does not appear to have a standalone company website. More concerning, independent lab testing by a third-party organization found that this product contained only a tiny fraction of the berberine listed on its label.

Quick Takeaways

  • CaelumCore Liposomal Berberine 1500 mg is sold on Amazon and other marketplaces but has no obvious standalone company website.
  • Independent testing by SuppCo reported that this product contained about 1% of the berberine claimed on the label.
  • The product is listed as one of Amazon’s “Overall Pick” choices for the search term “natural GLP”, helping it reach thousands of customers each month.
  • This case highlights a larger problem: many marketplace-focused brands are essentially labels on a bottle with little transparency behind them.
  • You can use simple checks (below) to avoid this kind of product and choose safer, better-documented options.

CaelumCore: A Brand That Exists Almost Only on Marketplaces

If you search online for “CaelumCore” or “Caelum Core Liposomal Berberine,” you will find:

  • Amazon listings for CaelumCore Liposomal Berberine HCL 1500 mg
  • Resellers and importers (Desertcart, Ubuy, ibspot, etc.) carrying the same product copy and photos
  • References to the brand name inside other companies' product descriptions (“our CaelumCore liposomal berberine”)

But what you won’t find is a clear, dedicated company site such as caelumcore.com with:

  • An “About” page explaining who is behind the brand
  • A physical address or phone number
  • Detailed quality or testing information hosted by the brand itself

This doesn’t automatically prove a product is bad, but it is a major transparency red flag. It means you are trusting the label on the bottle without any real way to verify who is responsible for it.

Independent Lab Testing: What SuppCo Found

SuppCo is an independent supplement testing and comparison platform. They purchase products directly (as a normal consumer would), send them to an ISO 17025 accredited lab, and publish the results.

According to SuppCo’s published data for Caelum Core Liposomal Berberine 1500 mg, the product was listed in their “Failed Products” section because it did not contain anywhere near the amount of berberine claimed on the label:

  • Claimed: 1,500 mg berberine per serving
  • Tested: approximately 9.29 mg berberine (about 1% of the label claim)

You can view the independent test information using the following links:

Amazon's “Overall Pick” — Despite the Failed Test

Adding to the confusion for consumers, CaelumCore Liposomal Berberine is currently listed as Amazon’s “Overall Pick” for the high-traffic search term “natural GLP” and similar GLP-1-related queries. Amazon awards this badge algorithmically based on sales velocity, click-through rate, pricing, and engagement, not on third-party testing or ingredient verification.

According to marketplace analytics estimates, this product sells more than 3,000 bottles per month on Amazon. This means a supplement that independent lab testing found to contain only about 1% of its labeled berberine content is still being actively promoted by Amazon as a top choice under a trending metabolic keyword.

This illustrates how quickly an online supplement brand can gain traction — even without a company website, published COAs, or verified potency.

How Amazon’s “Overall Pick” Algorithm Works

Many shoppers assume that Amazon’s “Overall Pick” badge reflects product quality, verified testing, or expert review, but the badge is generated entirely by Amazon’s internal algorithm. It does not evaluate whether a supplement actually contains the ingredients or doses listed on the label.

What the Algorithm Considers

  • Conversion rate: How often shoppers buy the product after searching a specific term such as “natural GLP.”
  • Click-through rate (CTR): How often users click the listing for that keyword.
  • Low return rate: Products with fewer returns or complaints rank higher.
  • Sales velocity: Fast-selling products rise quickly in the algorithm.
  • Prime eligibility & inventory stability: Being an FBA product with steady stock boosts ranking.

What the Algorithm Does Not Consider

  • Lab-verified ingredient potency
  • Independent quality testing
  • Manufacturer transparency or legitimacy
  • Long-term safety or consumer outcomes

For the search term “natural GLP,” CaelumCore’s listing likely rose in Amazon’s system simply because shoppers clicked and bought it at a high rate, not because the product passed any kind of quality evaluation. This is how a supplement can fail independent testing yet still be promoted by Amazon as an “Overall Pick.”

Important Caution

Earth Clinic is not affiliated with SuppCo and does not run these lab tests. We are simply reporting what an independent testing organization found. Any concerns or questions about methods and data should be directed to SuppCo.

However, if a product truly contains only about 1% of the active ingredient stated on the label, it is not delivering what you are paying for and may give you a false sense of security about your health regimen.

Why Marketplace-Focused Brands Can Be Risky

CaelumCore is just one example of a broader pattern. Many supplements sold on Amazon and other online marketplaces today are:

  • Created as private-label brands by individuals or marketers, not established supplement companies
  • Manufactured by contract facilities with many different brand names on nearly identical formulas
  • Listed with very high milligram doses that sound impressive, but may not match what is actually in the bottle
  • Promoted heavily with paid or incentivized reviews

While some marketplace brands are excellent and transparent, others exist only as a logo, a label, and a listing. If they disappear, there is no real company “home base” for you to contact or hold accountable.

How to Vet a Berberine Brand (or Any Supplement)

Whether you are considering CaelumCore or any other brand, here are practical steps to protect yourself:

1. Look for a Real Website & Contact Information

  • Search for the brand name plus “official site” or “about us.”
  • Check for a physical address, phone number, and email that look legitimate.
  • Be cautious if the brand exists only on Amazon and reseller sites.

2. Ask for or Download Third-Party Lab Results

  • Look for recent certificates of analysis (COAs), ideally batch-specific, showing:
    • Identity (it really is berberine)
    • Potency (the amount matches the label)
    • Contaminant testing where applicable
  • Reputable brands publish these directly or provide them upon request.

3. Be Wary of “Mega-Dose” Claims

  • If a product claims far higher doses than established brands, ask why.
  • Extremely high label claims can sometimes be a marketing tactic.

4. Check Independent Review Sources

  • Look at third-party testing organizations such as SuppCo.
  • Avoid relying solely on Amazon reviews.

5. Prefer Brands with a Track Record

  • Choose companies with a visible history, transparency, and consistent quality standards.

What This Means for People Taking Berberine

If you are taking berberine for blood sugar or metabolic support, a product containing only a tiny fraction of the labeled amount can:

  • Lead you to believe berberine “doesn’t work”
  • Delay effective health decisions
  • Waste money on ineffective products

The issue is not berberine itself, but quality control and labeling honesty.

Practical Next Steps if You Own This Product

  • Contact the Amazon seller to request batch-specific third-party test results.
  • Check independent testing sites (like SuppCo) for updated results.
  • Consider switching to a brand with:
    • A real company website
    • Published third-party testing
    • Clear manufacturing standards

Final Thoughts from Earth Clinic

CaelumCore’s failed lab test is not just about one brand. It highlights a growing issue in the online supplement industry: sometimes, what’s in the bottle simply does not match what the label promises.

Earth Clinic encourages readers to research carefully, seek transparency, and choose reputable supplement brands backed by real testing and accessible customer support.


Disclaimer: This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting or changing any supplement or treatment.