I have been dealing with cystic/hormonal acne since the end of college (about 5 years). Like clock work, I would get 1 or 2 very painful cystic pimples right before my period. And we all know these pimples can last an entire month, so by the time I finally got rid of one another was already appearing. This is due to the increase in testosterone levels in your body which cause your pores to tighten and acne to develope deep below the surface. I read about DIM online (which has a ton of good benefits) and started off taking just 1 capsule a day or sometimes 1 every other day (recommended dosage is 2 a day). I have now not had any cystic acne for 2 months since taking DIM-Plus. And remember I have gotten them EVERY month for about the last 5 years. Research DIM (Diindolylmethane) and find out all of the amazing benefits from this estrogen balancing supplement!