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Prion diseases are rare, fatal, neurodegenerative disorders/brain disorders caused by misfolded proteins that damage the brain, with Creutzfeldt-Jakob disease (CJD) being the most common form in humans; always progress to death within months to years after symptoms begin.
Causation: beef infected with Bovine Spongiform Encephalopathy (Mad Cow Disease), infected tissues during surgeries or transplants and other.
Prions and amyloid proteins are not the same, but prions are a specific type of amyloid protein that can cause infectious diseases by inducing misfolding by binding to normal proteins of the same type and forcing them into an abnormal, disease-causing shape that resists breakdown, leading to toxic clumps in the brain. While amyloids can form in various organs and are linked to several diseases, prions specifically affect the brain and are associated with neurodegenerative disorder; they can also impact other organs. Prions do not contain DNA or RNA.
Infectious: Yes, prions can transmit their misfolded shape to normal proteins, causing disease. No, amyloids are not infectious; they are aggregates that can cause disease but do not propagate. Prions: They are a subclass of amyloids all prions are amyloids, not all amyloids are prions
Internet search questions for further reading.
prions and amyloid proteins the same, phytochemicals that show prion-inhibiting activity, antiprion herbs/phytochemicals
Prion diseases include Creutzfeldt-Jakob disease (CJD), variant CJD, kuru, and Gerstmann-Sträussler-Scheinker disease. Amyloid proteins are associated with neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease.
Saliva tests are more effective than urine tests for detecting prions. I would think frequent testing would be required; for their are still unknowns about dosages for anti-prion phytochemicals.
Across diverse assays, particularly strong anti-prion phenolics include anthocyanins (Oenin, Myrtillin), chlorogenic/neochlorogenic acids, carnosic acid/carnosol, ellagic acid, pentagalloylglucose, EGCG and related catechol-type flavonoids, rosmarinic acid, myricetin, and punicalagin. Some show multi-step effects (blocking conversion, disaggregating fibrils, and reducing PrP^Sc in cells), but there is no single standardized potency ranking yet, and most data remain preclinical. Skullcap American and Chinese.
This is one disease you “DO NOT” want to treat yourself. Seek out Naturopathic Doctor, Functional Medicine Doctor or similar.
Amyloidosis coming in Part ll How to heal!
