Porokeratosis Remedies

| Modified on May 22, 2018
Apple Cider Vinegar
Posted by Mexicogirl (Chapala, Jalisco, Mexico) on 10/25/2010
1 out of 5 stars

I have porokeratosis. The spots have turned very red. Have started using Apple Cider Vinegar with mother but have not seen any improvement. Would like to know what other people have used with success. Any suggestions would be appreciated. Thank you.

Over the Counter
Posted by Christine (Hedgesville Wv) on 06/19/2015

Since Porokeratosis is a result of excess keratinization I have been trying to use a topical UREA cream 40% (known to break down keratin) I got the idea because many people swear by this cream for keratosis pilaris and as a callus remover. So far this seems to be working but it is very slow...My lesions are on my calves and thighs.

Apple Cider Vinegar
Posted by Tom (Regina, Sk) on 10/26/2010

I have never heard this term till now when I saw your post, so I admit to knowing nothing about this but can give you some ideas to try, to plot a course to carry out between you and your doctor.
To the PubMed site, part of NIH, part of HHS:

Type in 'porokeratosis' in the Search box at the top, and note it responds even before hitting Enter with a dropdown box of many suggested sub-names and topics! Do you know which type you have been diagnosed with? There's actinic, and there's ptychotropica...

Looking up one of the Searches yields this one:

Disseminated superficial actinic porokeratosis is characterized by multiple, brown, annular, keratotic lesions that develop predominantly on the extensor surfaces of the legs and arms during the third and fourth decades of life. No ideal treatment of disseminated superficial actinic porokeratosis has been found. We describe a patient with this condition whose skin lesions responded to topical tacalcitol.

Looking up tacalcitol, it is this:
Tacalcitol is a synthetic vitamin D3 analogue that is used to treat psoriasis. Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes. Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

Here is what the various D3 isomers look like, including tacalcitol:

So, the obvious questions to ask are:
1. What happens if you get lots of sun, say several hours per day? Does it get worse, or better, or neither?
2. Can you get a doctor to give you an Rx for the D3 skin cream used for psoriasis, to try on your skin for your condition? (This might involve "off-label use", which is allowed! 3. How much different can the body's metabolism be among the different isomers of D3? In other words, to see if the D3 taken internally might work instead of on the skin, have you tried taking a Vitamin D3 supplement for a few weeks consecutively at least, even up to the higher doses of 5000-10, 000 IU/day as recommended by several well known doctors like Wright and Williams?

BTW, if you're not Caucasian you will have a much harder time getting enough D3 made through sun skin action, even if in southern latitudes nearer the Equator and even if between 10 AM-2 PM! I hope you can find something useful in the above.

Lavender Oil
Posted by Veronica (Missouri) on 02/25/2017
5 out of 5 stars

Porokeratosis: I've been using lavender oil directly on the spot twice a day for a week and it cleared it up.

Lavender Oil
Posted by Ingard (Ca) on 05/21/2018

Is your poro keratosis on the sole of your feet? Are you still free of it. Did you make your own lavender oil? Thank you for responding

Over the Counter
Posted by Bandy12 (San Antonio, Tx) on 08/10/2011
4 out of 5 stars

I have had this condition for some time. The doctor prescribed the usual medication, Carac cream. If that helps at all, it is very very slow. I have mostly the red irritated spots that contain lumps of keratin--some are linear and some are round with raised edges; those raised edges also contain keratin. The round ones with raised edges are the hardest to get rid of. The only solution that works well is to completely clean out the spots. The keratin is actually wedged in the pores and is difficult to get out. Unfortunately, I use my fingernails for lack of a better method. After the keratin and debris are out the spots will heal rather quickly by using an acne medication, 2% salicylic acid (over-the-counter).

Over the Counter
Posted by Debbie (Nc) on 04/17/2016


Did you get good results with this cream?