Mast Cell Activation Syndrome
Natural Remedies

Natural Remedies for Mast Cell Activation Syndrome (MCAS)

| Modified on Jun 20, 2023
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MCAS, also known as Mast Cell Activation Syndrome, is a condition where a person experiences repeated allergic symptoms such as swelling, hives, swelling, low blood pressure, difficulty breathing, and severe diarrhea.

High levels of mast cell mediators are released during those episodes. Mast cells are allergy cells responsible for immediate allergic reactions. They cause severe allergic symptoms, by releasing compounds called mediators stored inside or made by the mast cells.

Causes of MCAS

MCAS can be caused by the following:

  • Viral, Bacterial, or Fungal infections
  • Heavy metals
  • Herbicides
  • Mold Poisoning
  • Food or environmental Allergens
  • Genetically predisposed

Natural Remedies for MCAS

Continue reading to learn what Earth Clinic readers have tried or learned for this condition.

MCAS and C Diff

1 User Review
5 star (1) 

Posted by JGaston (soAZ) on 10/22/2022


I found your page after researching and having second thoughts about taking the antibiotics prescribed. Unusual case.

I have an autoimmune disease called Mast Cell Activation Syndrome (MCAS). Every person experiences something different. This go around… GUT. My disease decided to come out of remission in Jan 22; this after a year of trying to get into a GI Dr about my chronic constipation.

After many failed attempts to actually see and get any procedures done (I.e., bloodwork, Sibo/leaky gut check) I decided to take my health back and not “totally” rely on my PCMs. I say this because… in reality I need all the help I can get. Sorry, I digressed.

Fast forward 9 months without answers. 9 months on H1&H2 antihistamines; of constant bloating, redness, and constipation.

9 months of reporting this to my team of physicians (holistic as well now) w/o anything other than… change your diet (Low Fodmap), take miralax…keep on with meds…

Then interestingly enough constipation turns into diarrhea with mucus. Same again, informed PCM and others… action = NOTHING! I asked for a stool sample to rule out parasites and or mold. Again, I ASKED! All of a sudden, “you have C Diff, it's contagious, detrimental to your health… need antibodies ASAP…. Etc! ” STOP! How did I get this??? PCMs…. Read off summary sheet, me… none apply.

One day on antibiotics and I threw up and instantly regretted it. Tightness in chest. Wheezing. Not good. So I instantly stopped and started researching MCAS and C Diff… C Diff new findings… and here we are 10/22.

Besides my gut being already compromised, I believe it was the H2 antihistamines (PPIs) that sent me over, that and possibly Long Haul Covid which seems to be a long lasting side effect of Covid, per NIH.

I've been on the probiotic/ACV/Fermented foods for a week however today something wonderful and crappy occurred. I emptied my bowels (remember… constipation = high histamine = inflammation/autoimmune) and went back into diarrhea. Though I was second guessing myself about all of this… thank goodness for a daily journal… I realized that in addition to feeling good and all, I accidentally took some cleansing herbs w/o thinking.

So long story short… take your time! Write down what you're doing. Don't overdo on the many other symptoms! Focus on one… C Diff!! Everything else will fall into place.

Read gut-brain connection and vagus nerve. Amazing insight into our guts!

Thank you for this website!! Lifesaver!!


Replied by Sam

MCAS description as written by EC is incorrect. What you describe, your symptoms are also not very indicative of MCAS. I recommend you complete full course of NAET.

Replied by Sharon
(Ottawa, Il)

Clinical paradigms test for MCD and Dr Paolo Bolognese for eds. eds society. Myle Skoby measures bones in the cervical. Ligament laxity? Hypermobility or cervical cranio instability. Most eds people have mcd