The Science of Omega-3s: Beyond Basic Supplementation

| Modified on May 09, 2026
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Omega-3 fatty acids are essential fats that play a critical role in brain function, cardiovascular health, inflammation control, hormone signaling, and cellular repair. Unlike some fats the body can manufacture on its own, omega-3s must primarily come from food or supplementation.

The three major forms of omega-3s are:

  • EPA (Eicosapentaenoic Acid): Primarily associated with inflammatory balance, mood support, and cardiovascular health.
  • DHA (Docosahexaenoic Acid): Critical for the brain, eyes, nervous system, and cognitive function.
  • ALA (Alpha-Linolenic Acid): Found in plant foods such as flax and chia, though conversion into EPA and DHA is often limited.

Over the past two decades, omega-3 fatty acids have become one of the most extensively researched nutritional compounds in modern medicine. Earth Clinic readers frequently discuss omega-3s for brain fog, dry eyes, joint stiffness, cardiovascular health, inflammation, mood balance, and healthy aging.

At a Glance: Key Benefits of Omega-3s

  • Brain & Mood Support: DHA and EPA support cognitive health and emotional resilience.
  • Heart Protection: Omega-3s help regulate triglycerides and inflammatory signaling.
  • Inflammation Resolution: Precursors to SPMs that actively resolve inflammatory cycles.
  • Metabolic & Healthy Aging: Supports insulin sensitivity, mitochondrial health, and biological longevity.

Quick Nav:

The Different Types of Omega-3s
Brain, Mood & Cognitive Benefits
Cardiovascular & HRV Benefits
Inflammation & Joint Health
Eye and Skin Benefits
Metabolic Health & Insulin Sensitivity
Longevity and Healthy Aging
Best Food Sources
Choosing a Quality Supplement
How to Take Omega-3s
Safety and Side Effects
Frequently Asked Questions


The Different Types of Omega-3s

Not all omega-3 fats function identically in the body.

  • EPA: Often associated with cardiovascular support, mood balance, and inflammatory regulation.
  • DHA: Highly concentrated in the brain and retina, where it supports nerve signaling and visual function.
  • ALA: Found in flaxseed, walnuts, hemp, and chia seeds. The body converts only a small percentage into EPA and DHA.

Most research showing significant health benefits focuses on EPA and DHA from seafood or marine-based supplements.


Brain, Mood & Cognitive Benefits

DHA is considered one of the most important structural fats in the brain. Omega-3 fatty acids help support neuronal membrane flexibility, communication between brain cells, and blood flow to brain tissue.

Earth Clinic readers frequently discuss omega-3s for:

  • Brain fog and mental clarity
  • Mood balance and stress resilience
  • Focus and concentration

The Gut-Brain Axis: Emerging 2026 research highlights Omega-3s as "prebiotic-like" factors that support beneficial gut bacteria like Akkermansia, which strengthens the gut lining and influences mental health through the vagus nerve.


Cardiovascular & HRV Benefits

Omega-3 fatty acids are best known for their effects on cardiovascular health. Beyond lowering triglycerides and supporting vascular flexibility, Omega-3s are increasingly studied for their impact on Heart Rate Variability (HRV) and autonomic nervous system balance. High levels of EPA/DHA are associated with improved vagal tone and better stress recovery.


Inflammation Resolution (SPMs)

Omega-3s don't just "block" inflammation; they are precursors to Specialized Pro-resolving Mediators (SPMs). These molecules act as the body's "stop signal" for inflammation, actively clearing out cellular debris and restoring tissue balance after an injury or infection.

Many readers report benefits for:

  • Joint stiffness and arthritis support
  • Autoimmune-related inflammation
  • Muscle recovery after exercise

Metabolic Health & Insulin Sensitivity

Recent studies emphasize the role of Omega-3s in metabolic flexibility. By incorporating into cell membranes, these fats help improve insulin sensitivity and support healthy blood sugar regulation. This makes Omega-3s a foundational supplement for those focused on metabolic health and weight management.


Eye and Skin Benefits

DHA is heavily concentrated in the retina and plays an important role in visual function. Readers often discuss omega-3s for dry eyes, screen fatigue, and skin hydration. When paired with antioxidants like astaxanthin, Omega-3s provide enhanced protection against blue light and UV-induced skin aging.


Longevity and Healthy Aging

Omega-3s are foundational for mitochondrial function and biological resilience. Recent research suggests that maintaining a high Omega-3 Index (a measure of EPA/DHA in red blood cells) is a strong predictor of lower all-cause mortality and healthy cellular aging.


Best Food Sources and Sustainability

Whole-food sources remain the gold standard. To minimize toxin bioaccumulation (mercury/PCBs), prioritize small, cold-water fish (SMASH: Sardines, Mackerel, Anchovies, Salmon, Herring).

  • Algae-Based DHA: A primary, sustainable source for vegetarians that bypasses the middleman (the fish).
  • Sourcing: Look for IFOS Certified products to ensure purity from heavy metals.

Choosing a Quality Supplement: Bioavailability

Not all supplements are bioavailable. For maximum absorption, understand the chemical form:

  • rTG (Re-esterified Triglyceride): Up to 70% better absorption than common Ethyl Esters found in budget fish oils.
  • Phospholipids: Found in Krill oil, these are often considered superior for brain barrier penetration.
  • Freshness: Rancid oil creates oxidative stress. Always check for a clean, non-fishy smell.

How to Take Omega-3s

Omega-3s are fat-soluble and are absorbed significantly better when taken with a meal containing other healthy fats (like avocado or olive oil). Many Earth Clinic readers find that storing fish oil in the refrigerator reduces reflux and "fish burps."


2026 Safety and Side Effects

Important: High-dose supplementation may increase bleeding risk, especially for those on anticoagulants. Consult a professional if you have upcoming surgery or a history of atrial fibrillation.


Frequently Asked Questions

What is the Omega-3 Index?

It is a blood test that measures the percentage of EPA and DHA in your red blood cell membranes. An index of 8% or higher is generally considered optimal for heart and brain health.

Can I get enough Omega-3 from Flax?

Flax provides ALA, but the conversion rate to EPA and DHA is often below 5-10%. Most people benefit from direct marine or algae sources.


Insights from the Earth Clinic Community

Earth Clinic readers have consistently found Omega-3s to be a foundational nutrient for brain health, joint comfort, and healthy aging. By pairing Omega-3s with magnesium, Vitamin D3/K2, and anti-inflammatory nutrition, our community continues to pioneer holistic recovery strategies. Explore the reader experiences below and share your own journey!


The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.

ADHD


Posted by Roxanne (Perth, Western Australia) on 12/09/2007
★★★★★

High Potency Fish Oil w/ Virgin Evening Primrose Oil Has Made My Little Boy "Normal" I have two children aged 3.5yrs and 21 months. My eldest was diagnosed with Autistic Spectrum Disorder at the start of the year (Jan 2007). Because my eldest son is classed as Autistic, the health professional seem to think that my youngest may have a problem. Okay, my youngest is very hyperactive, used to run into things (like the kitchen table) and not feel any pain and he had a serious biting problem that went waaaayyy beyond teething. After geting sick and tired of hearing "your youngest maybe suspected Autistic/ADD" I decided to see a homeopath and ask (beg) for help. The lady there was wonderful and recommended that I try a mixture of high potency fish oil that also contained virgin evening primrose oil that was recommended for children and adults of all ages. Well, after a week of giving him 5ml a day (mixed with food), our little boy is all cool. calm and collected. He stills runs around but he has stopped running into walls and tables. The biting was gone and he interacts well with his autistic brother. He has also started talking again. And to think, only 2 weeks have passed now and he will only improve. Just wanted to share this with you. Thanks,

Replied by Jessica
(Long Island, NY)
01/26/2009

Thank you so much for sharing this! Jessica

Replied by Bob
(Moosic, Pa./usa)
04/14/2012

Many moms who have autistic children were dehydrated while pregnant. Main causes of dehydration are drinking caffeine, alcohol or soda & lack of water & sea salt.

Google: Autism caused by dehydration.


Anxiety


Posted by Sharon (Boston)
★★★★★

First I took flax, then I switched to Cod Liver Oil from Norway (no mercury, contaminants, etc). I think I was taking 2 capsules a day. After 2 days I had a sharp pain in my gall bladder which I get if I eat too much fat. I stopped taking the cod liver oil and the pain went away. I went to Whole Foods and found an excellent brand of flax oil with 15% flax seed particles. There were only a few bottles left so I figured it must be a good brand! At any rate, I noticed quite by accident that, after increasing the flax to 3 capsules 3x a day, my anxiety and adrenaline decreased. I knew flax seed oil has been used sucessfully in the treatment of depression and bi-polar disorders, but I didn't know that flax oil could also diminish anxiety! Needless to say I am unbelievably pleased to discover this. Last week I took a break from the flax oil and my anxiety returned as usual after a couple of days. I hope others will try flax for anxiety and write in about it. I would be curious to know if it has the same effect on others.

Replied by Jared
(Sydney, Austrailia)
03/05/2009
★★★★★

I suffer with social anxiety disorder, I'm anxious and have difficulty thinking clearly in general not just in anxiety situations.I got myself flaxseed oil and took a tablespoon.I felt better instantly. My thinking became a lot clearer and my usual confused anxious state diminished. It definitely has a significant effect on brain chemistry. I'll be taking it everyday now :)

Replied by Cynthia
(London, Uk)
01/23/2012
★★★★★

I started taking 2 tablespoons per day of ground flaxseed (or flaxseed meal), in the hopes of shrinking the many large fibroids in my uterus, and easing fibrocystic breast pain.

I've been taking it for less than a month, and I'm guessing that it's too soon to tell if it has helped with these things, or at least it doesn't seem to have helped so far.

But, I have noticed some positive effects in other areas. I am normally a very anxious person, but since starting the flaxseed, I feel much calmer and able to handle everyday situations. My asthma has also seemed to improve drastically, (probably as a result of me being calmer). I have hardly taken any asthma medication since I started taking it.

I will definitely continue to take this. I'm happy with the results so far, and really hope that in time it will also help me with the fibroids and breast pain.


Beautiful Skin


Posted by Linda (Melbourne, Australia) on 11/11/2007
★★★★★

Hi all, I have been taking flaxseed oil for about 3mths 4 tablespoons a day so i decided to use it as a mosturiser on my face, i do suffer from acne as well im 40 and never looked my age after about a week i noticed a difference in my skin and it started to clear up my acne its been 4 weeks now and i am so happy my skin glows and looks so healthy, people have started to comment how good my skin looks, as well as the flaxseed oil i use vco with it, it helps me maybe it could help others, you can find it in a fridge in health food shops cost $11 and last for couple months. Hope others find it good as well. cheers Linda

Replied by Roslyn
(Queens, N.Y.)
11/01/2009

Hi Linda from Melbourne Australia. I take omega everyday and also suffer with acne. You use the flaxseed oil as a moisturizer do you put it on day and night? If you apply during the day do you also use SPF sunblock as well? You said it helped with your acne - did you break out before it got better? Also what is vco? I have cut sugar, diary and deep fried foods out of my diet which helps alot. Thanks. I will appreciate any advice that you have.

EC: VCO is an acronym for Virgin Coconut Oil.

Replied by Jenay
(Los Angeles, California)
03/16/2010

hello,,i was wondering if is possible to mix flax seed oil with acv and baking soda?


Beautiful Skin
Posted by D. (Los Angeles, CA)
★★★★★

I was taking Fish Oil for about a month until I started hearing about about the mercury content in fish. I switched over to flax seed oil. With both fish oil and flax seed oil, I noticed overnight that my skin became noticeably softer and less dry. It took a couple of days before my system adjusted to taking 1 capsule of flax, 3x a day -- it's commonly used as a laxative! Another thing I noticed from taking Flax Seed Oil along with Calcium/Magnesium/Phosphorous liquid is that I feel much calmer.

Replied by D.
(LA)
08/07/2008
★★★★★

Update to my flax post... After trying out a bunch of brands over the past few years, I finally bought one that tastes good! Okay, so this is an a rare Earth Clinic product endorsement and no, EC didn't get a free bottle from the manufacturer! The brand name is Barlean's and you can find it in the refrigerated section of Whole Foods. I take 1 tablespoon 3x a day on an empty stomach. No stomach problems, believe it or not. This one tastes a whole lot better than the other brands I have tried. Most of them have that terribly rancid after-taste.

Re: the skin -- yes, if you want dewy, moisturized, baby soft skin, flax is the way to go. Takes 20 minutes after eating a tablespoon of flax oil to see the results in my skin. It definitely softens my forehead creases. If you have tough, dry hands or cracked heels, this remedy is for you! The only problem is that effects of 1 tablespoon only lasts about 8-10 hours... But then another 24 hours to go back to the way your skin was before the flax...


Broad Benefits


Posted by Giny (Denver, Colorado) on 10/07/2011
★★★★☆

My 19 years son has been struggling with ADD and depression since he was 8 years old. I have tried many remedies, but those only work to some degree. I have tried many prescriptions but none of these work, not mention too many side effects.

I come across the symptom of omega-3 deficiency at web two weeks ago. The symptoms of omega-3 deficiency are acne, dandruff, dry eyes, ADD, depression, joint pain, chicken skin on the back of arms, etc., which match the symptoms my son has. So I decided to give my son fish oil just for the heck of it, and it does help my son's concentration and depression issue. Since it only has been two week, it may not show significant improvement, but it does make some difference. My son does not eat dairy products, and it helps, but not completely. Maybe omega-3 is the missing piece of the puzzle. I will keep everybody posted.

Replied by Timh
(Louisville, Usa)
10/11/2011
2041 posts

Giny, also consider adding either borage, evening primrose, sunflower, or safflower to already cooked foods, along with omega 3 fish for a more pronounced effect. Music therapy could also be helpful.


Canker Sores


Posted by Jennifer (Northern, Idaho) on 01/28/2008
★★★★★

I was having chronic canker sores, usually 3 at a time. I tried everything I'd ever heard of with little success. I started taking Omega 3 in the form of flax seed oil for general health reasons. Within a week or so my sores were gone and I haven't had one since. I alternate between flax oil capsules (6 a day), ground flax seeds (2 tablespoons) and eating about 1/4 cup of walnuts.

Replied by Linda
(Springfield, Oh)
01/17/2010

I had serious canker sores and finally realized it was an allergy to sulfates (a cleansing agent) in most toothpaste. Now I try to use other toothpastes before bed (when the residue is staying in your mouth) and regular in the AM.


Cholesterol


Posted by Betty (USA)
★★★★★

My cholesterol is 6.33. The doctor said I had to go on cholesterol drug but I tried out two of them and had a bac reaction. So, I went to a health food store "ROOT CELLAR" here in Charlottetown and tried cholesterol tablets but had trouble with them. So, I bought their "Omega-3 fish oil" ...I've only been on it for two weeks...too soon to tell if cholesterol level is down but I must say that I feel much better after so short a time on Omega-3. It says on the bottle that it's made from HERRING. Other stores have oil made from salmon but this store has a good reputation so I bought oil there.

Replied by Jessica
(Long Island, NY)
01/26/2009

Try Red Yeast Rice, I think thats the name, my sister has a Herb shop and my Mom took it and her numbers became normal! Jessica


Cholesterol
Posted by Rebecca (Allen, MI)
★★★★★

I have been taking blood pressure medication for over one year. I heard, from two different sources, about using ground flaxseed & thought I would give it try in order to "wean" myself from prescription drugs. I have been amazed at the results. I take a total of 4 tablespoons a day - usually 2 in the morning & 2 at night. I usually just mix it in water but sometimes I put it in my food (oatmeal works well & so does soup). I have been using it for 6 weeks and have decreased my meds from 20 mg a day to 5 mg a day!! My blood pressure has been more stable and MUCH, MUCH lower than when I took the full dose of my daily medication. It really does work. My goal was to be off prescription medication by January 2006 but I think I will make well before then!!!


Constipation


Posted by Janine (Catskills, NY)
★★★★★

If you have constipation, taking a capsule of flax seed oil with some water first thing in the morning works wonders. Give it 20 minutes -- make sure you don't go anywhere, this stuff works fast! It is an excellent way to cleanse the bowels as well.


Constipation
Posted by Amanda (Santa Barbara, CA)
★★★★★

I found the following information below in quotes from a website after reading that the ALA (there is no DHA or EPA)in flaxoil can cause an eicosanoid imbalance in the body leading to increased inflamation and ill health. I take the fish oil to get the EPA and DHA that balances eicosanoids and protects brain cells. I take 1000 mg of molecularly distilled fish oil to avoid any pcb's or dioxins and borage oil for the proper balance of omega 6.

"Omega-3 (you may sometimes see it written as n-3 or w-3) is the name given to a family of polyunsaturated fatty acids. The parent omega-3 - alpha-linolenic acid (ALA) - is described as 'essential' as, like vitamins, it must be obtained from diet. It is polyunsaturated and has 18 carbon atoms and 3 double bonds (18:3).

However, from the point of view of human nutrition, the long-chain omega-3 fatty acids eicosapentaenoic acid (20:5)and docosahexaenoic acid (22:6) - EPA and DHA - are considered much more valuable as these are the forms the body requires. In theory, humans are able to synthesise EPA and DHA from dietary ALA, but in practice this process is inefficient. Scientists have therefore concluded that EPA and DHA should be obtained from diet. Oil-rich fish and supplements such as fish oil and cod liver oil, are the richest and most readily available sources. Other sources such as krill and fortified everyday foods like bread and fruit juices are in production in a minor way in various parts of the world.

Replied by Jon
(Wheeling, Wv)
09/12/2018

I am reading conflicting reports as to the benefits of Omega 3's. I am a picky eater and do not eat much fish. I would like to take supplements to protect my body. I have seen Omega's advertised that are supposed to be "pure" and in blister packs for freshness. You have to sign up to have shipped every month. I tend to stay away from those type of products. It is very hard to navigate the web to find a good yet cost effective brand to buy. Do you know of any reputable sites that I could check?

Replied by Charity
(Faithville, Us)
09/12/2018

Ray Peat has some very insightful arguments with scientific data to encourage people not to use fish oil supplements if you want the research information on the topic.


Depression


Posted by Calista (Penang, Malaysia) on 01/03/2009
★★★★★

Fish Oil (Omega 3 Fish Oil) REALLY helps with depression. I have been battling severe clinical depression for over 2 years now. Though I'm emotionally & mentally better, I had problems with irregular sleep pattern, excessive sleepiness and lack of energy. I read that Omega 3 can help, so I tried taking it. After just 3 days on 3000mg a day (taken on breakfast, lunch, dinner), for the first time in years I noticed I slept less during the day and slept better at night. It's been weeks now and I continue taking 1000-3000mg a day, and I keep feeling better. I now wake up feeling more refreshed and motivated to do things. I have the energy to actually do them. My naps are short, or sometimes I can go without one. I feel sleepy after a certain time (at night) and can actually sleep throughout the night and wake up ONLY when it's morning. It has regulated my sleep cycle! I can't remember the last time I feel this great! It's amazing such improvement can be achieved with just a simple thing like Fish Oil. Do try it. There can be no harm, only good.


Dogs


Posted by Elaine (Bettendorf, Iowa) on 08/04/2008
★★★★★

First thank you for the amazing amounts of help you share. Through the inspiration of your readers I decided to put my Golden Retriever older puppy on a more informed diet than feeding her retail store junk. I give her a natural kibble and she is doing well. In the interest of protecting her joints in old age I have her on a supplement. To take it one step further I give her a teaspoon of flaxseed oil in her meals each day. After six months I noticed that she is not shedding profusely as a former golden did. I do brush her regularly but there is no excessive hair all over the house. Plus I noticed that her pads are very soft. Perhaps this could help a hair challenged pet owner out there? Aside from strengthening her body she has the benefit of a very healthy coat!

Replied by Lula
(Australia)
11/04/2016

Please be careful supplementing your dog - if you are feeding flax, you "must" feed vitamin e, (natural), which has the role of stopping fats becoming rancid in the body. It is a long story, but I found out the hard way :(


Fibroid and Breast Cancer Prevention


Posted by Ruth (Ionia, Michigan) on 03/09/2008
★★★★★

my name is ruth,I used flax seed to cure my tumors . I would grind them in my coffee grinder . Then I would use about 2tsp a day and sprinkle them over my salad . I found it easier to eat them that way . I also would make flaxseed bread I would use about a 1/2 cup in my loaf of bread . It is very important to grind the flaxseed up to get the benfit of the seeds. Other wise the seeds will just pass right threw you . I did this for about a year and when I went back and had my ultra sound they were gone . I also had a tumor in my breast . I was benine but that also disappeared as well . I never tryed the BSM because I never heard about it working on' tumors until now. I end up have a historectomy because my uterus fell . but I still take it so I don't get any tumors in my breast


Fish Oil

Posted by Rebel (Somewhere, Usa) on 09/07/2014

Hello all. My mother goes to church with a lady, that is having some real bad problems right now. I am not sure what all is going on, but she took the midi doc route. Believe it or not the medical doctor actually told her she needs to take Fish Oil that dissolves in the intestines and not the stomach. She forgot to ask him what type that was.

I was hoping maybe some of you Fish Oil people may know the kind, not so much brand. But the kind that will dissolve after it is in the intestines and not the stomach.

Thank you.

Replied by J
(Canada)
01/12/2015

Hi Rebel, that just means it is the kind of fish oil capsule that has an enteric coating on it. This coating (often synthetic but can be found plant based) is resistant to acidity and therefore can't be broken down in the stomach. So it passes through into the intestines, where it finally breaks down in the non-acidic neutral conditions there and is absorbed.


Fish Oil and Skin


Posted by Art (California) on 07/31/2022 2875 posts
★★★★★

Editor's Choice

In early June of 2022, I was having a conversation with a friend who I was already working with to try and resolve hyperpigmentation issues of her skin. Progress was slow and she was asking about different supplements that might be helpful. She mentioned that she was taking fish oil (FO) and it didn't seem to be too helpful, even though she had been taking it for years.

I asked her how many milligrams of FO she was taking. She mentioned that she was taking a 1000 milligrams a day of combined DHA/EPA. I mentioned that that might not be the optimal dose for her based on effective dosages used in studies of FO in humans and suggested she consider upping her dose to study levels of EPA/DHA of 3 to 4 grams per day in order to optimize the benefit to her skin and heart. This would be 3 to 4 times the amount she was already taking. It is the total amount of EPA/DHA in a given FO soft gel that is important, not the total amount of different oils. So even though a FO soft gel may say 1200 mg, the actual EPA/DHA level may only be half that amount. It is important to read the label carefully to know what you are really getting.

Obviously the heart benefit will not be readily apparent other than through testing, but I told her that any additional benefit to her skin should be readily apparent within two months or so. I also reminded her that FO at therapeutic dosing such as she was now taking can absolutely have blood thinning effects and as such she should notify her doctor and have him/her add that information to her medical records for safety. I further told her that the high dose FO, because of its anti inflammatory effects should be additionally beneficial to her anti hyperpigmentation regimen as localized inflammation is a contributing factor to skin hyperpigmentation.

This past week, my friend texted me to update me on how she was doing as it was approaching the 2 month mark at her new increased FO dosing level. She said the following, it appears to be additive to her anti hyperpigmentation regimen as she could see increased fading of dark spots which she said had previously slowed to a crawl and she felt that if the current rate of lightening continued she might be "clear" in 3 months or so. She further said that the increased FO dosing schedule had eliminated "all of her dry skin" issues which she said had been a major problem for her for years. She went on to say that "stretch marks, keratosis and scars" that she has had for years had either faded, significantly diminished or both.

Overall she was very happy and looking forward to continued improvements and she said the improvements are helping her to diligently stick to her current regimen with no slacking. I told her that was good that she is applying her regimen consistently because that is needed in order to obtain the results she is getting and wants.

She told me she would update me later and when she does I will update this thread to update on her progress.

I know this is not of very much importance to many people, but it does offer a significant boost to her self esteem which, imo, is very important in trying to improve your overall quality of life, plus the added health benefit that the therapeutic FO dose is having to her heart is great, especially as we age! It is important to highlight the benefits of FO at useful dosing levels as many studies spotlight a multitude of health effects associated with sufficient intake of EPA/DHA, even for the brain!

Art

Replied by Madelyn
(Idaho)
08/03/2022

Hi Art,

This is fascinating information. Thank you for sharing your friend's experience with fish oil's effect on her skin. I would really like to know which brand she took. Fish oil quality seems to be all over the place depending on the brand, so I'd like to try the brand and formulation she is using. Thanks for ALL your amazing contributions to the EarthClinic community!

Art
(California)
08/03/2022
2875 posts

Hi Madelyn,

You're welcome!

This is the product she used:

She takes 4 per day.

Art

Peter
(Chicago)
08/11/2022

Art, you mentioned fish oil for end stage kidneyDisease, is this brand ok to use?

Replied by Madelyn
(Idaho)
08/04/2022

Thanks for the link, Art! I've used Innovix Labs probiotics before at the recommendation of others. They seem to be an excellent brand for supplements.

Art
(California)
08/11/2022
2875 posts

Peter,

Imo, this fish oil (FO) supplement is an economical way to get into that range of EPA/DHA with the least amount of soft gels per day. You can spend much more, but I'm not sure how much more you might be getting for the extra cost. I take it myself, but have no way of analyzing it to determine the absolute quality of it.

With something as serious as CKD, you will definitely want to get your doctors approval for safety and to insure that it is not contraindicated with any current meds. FO has blood thinning effects that you should be aware of.

It is also very important for people with CKD to be aware of the fact that CKD puts you at increased risk for Cardiovascular disease (CVD) :

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/410928#:~:text=Chronic kidney disease (CKD) is a risk factor for cardiovascular, increase in all-cause mortality.

Both Melatonin and FO offer heart protective effects and fight atherosclerosis and this is very important information for anyone with CKD.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7023944/#:~:text=In summary, fish oil may, and rupturing of atherosclerotic plaque.

https://www.hindawi.com/journals/omcl/2018/9286458/

Art



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