Evening primrose works like magic for PMS symptoms, especially tender breasts. This was a big problem for me each month and was a disruption in my life. Two weeks before my period my breasts would begin hurting and gradually became worse as my period neared. I began taking evening primrose capsules and now have no pain at all. I begin the capsules as soon as I ovulate. I take one in the morning the first week after ovulation. The second week I take one in the morning and one at night. As soon as I start my period, I stop taking them until next month. It really works and has no side effects as far as I can tell.