I was at Trader Joe's last week and was browsing through their line of supplements. One supplement in particular caught my eye - sublingual folic acid, b6 and b12. I had been seeing some good information on the web about the b vits, so I decided to buy it. (cheap by the way.) The one thing I noticed immediately is I am in such a darn good mood after I take it! I forgot to take one pill 2 days ago and some pms irritability set in. Took my vitamin and within half an hour, my mood improved. I think this may be a great supplement for those with depression or anxiety. Here's some info about folic acid on Dr. Mercola's site: http://articles.mercola.com/sites/articles/archive/2002/07/06/folic-acid-part-two.aspx. So it may be the folic acid that is enhancing my mood, I don't know.