During the early 80's I had an eating disorder. It was not to the point where I would throw up however I could eat a dozen donuts and then go out for pizza. It was like there was no shut off. Then I would fast and run and work out to undo the damage. One Thanksgiving I ran 11 miles in the pouring rain after dinner then went back in and ate half a pie.
I attended a health fair and there was a speaker there-a PHD specializing in anorexia and bulemia. I told her what was going on and she asked how much diet soda I drank a day. It was considerable amount. I drank it instead of eating after a binge. She told me to not use sacharrin again and the problem would go away. It affected the appetite she said.
So I stopped using saccharine and the problem cleared right up.