D-Mannose for Bladder Infection


5 star (33) 
  85%
4 star (1) 
  3%
3 star (1) 
  3%
1 star (3) 
  8%
(1) 
  3%

Showing 5 Star Reviews

Art (California) on 08/15/2025
5 out of 5 stars

One of my neighbors would get UTIs every month due to a problem surgery related to her bladder she had when she was much younger. She had asked me if there was anyway to avoid this problem so she wouldn't have to take the Ciprofloxacin (cipro) that her doctor always prescribed because she was having tendon issues in her feet and felt it was likely being caused by the cipro. I told her that the tendon issues with cipro are well known.

I suggested that she drink two bottles of D-Mannose water each week, spread as evenly apart as possible and that should help prevent most if not all of her monthly UTIs. I suggested drinking one bottle on Sunday morning and one bottle on Wednesday afternoon.

I told her to just take a 500 ml bottle of filtered water and add 1 1/2 teaspoons of D-Mannose powder to each bottle and shake well until dissolved and to drink two of these bottles each week. She started as soon as her D-Mannose package of bulk powder arrived.

It has been over two years since she started this regimen, so I asked her the other day how it was working out for her. She looked at me and smiled and pointed to a bag of D-Mannose powder on her counter and said she hasn't had a UTI since she started drinking it twice a week and I smiled back!

D-Mannose is said to bind to E coli. which is the most common bacteria to cause UTIs at about 80% to 90%, but her doctor had previously told her that her UTIs were caused not just by E coli., but other bacteria on occasion. So perhaps D- Mannose can bind to the others as well?

I just don't understand why doctors don't even consider something like D-Mannose, that has a good safety profile, as a preventative or treatment instead of prescribing potent antibiotics that can cause other health problems. She didn't mention having any problems with taking D-Mannose twice a week.

Art

REPLY   9      

Nick (London, UK) on 12/23/2024
5 out of 5 stars

Pretty much all the posts here about D-Mannose are from women, which is makes sense as UTIs are most common among women. I just wanted to let you all know it works amazingly well for men too (i.e. me! ) I had a recurring UTI this year that kept returning, even after 5 courses of antibiotics (Nitrofurantoin at first, then Ciprofloxacin). After the last course, my doctor suggested trying D-Mannose, 2000mg a day. It worked - it cleared up completely, and I've been clear for well over a month. Judging by the numerous 5-star reviews I've read here, it must be more than a co-incidence. I'm continuing with the D-Mannose for a while, just to be sure.
REPLY   11      

Art (California) on 08/16/2020
5 out of 5 stars

Having an alternative to antibiotics for UTIs is a useful thing for at least three reasons. One, antibiotics can have significant side effects and two, bacteria can become resistant to antibiotics and if you are prone to frequent UTIs, you can eventually run out of reasonable antibiotic options. Three, antibiotics can kill needed good gut bacteria and thus lead to further complications.

The active component against UTIs in cranberry/cranberry juice is D-Mannose, a common supplement. D-Mannose is much more potent and works by binding to the E.coli bacteria preventing the bacteria from sticking to the urinary tract surfaces and bladder interior surface, allowing the bacteria to be safely flushed away when urinating, preventing the infection from spreading or continuing to exist. Because of this method of action, bacterial resistance to D-Mannose does not occur because D-Mannose is not attacking the virus, but rather just binding to it. This can become a major problem with antibiotics which the bacteria become resistant to.

Another issue with antibiotics is that they tend to destroy the gut bacteria both good and bad and this can contribute to more UTIs in the long run if good gut bacteria is destroyed that would normally keep E.coli controlled. Here is a link to a study where they show that D-Mannose can be used as a preventative for frequent UTIs in women who are prone to these infections, but my experience is that it is also effective in men, but women get significantly more UTIs than men :

https://pubmed.ncbi.nlm.nih.gov/32597599/

Many people who have frequent UTIs develop bacterial resistance and then stronger and stronger antibiotics are needed to try and fight the UTI, but these more potent antibiotics can bring a myriad of side effects that nobody wants or needs! For example, one highly potent antibiotic that can be used for UTIs is Ciprofloxacin / Cipro and this particular antibiotic has the well known side effect of causing torn tendons and ligaments and blown achilles tendons (OUCH!). I wrote about this serious issue in another EC post and explained how to help repair some of this ligament and tendon damage.

D-Mannose is thought to be effective only against E.coli based UTIs which means it will not likely work for all UTIs, but it will work for the majority because E.coli is the most common cause of UTIs at approximately as high as 90% of cases.

https://www.ucsfhealth.org/conditions/urinary-tract-infections#:~:text=The most common bacteria found, 90 percent of the time

D-Mannose can also be used as a preventative against UTIs when traveling to help prevent a UTI from getting started in the first place. Here is a link to typical D-Mannose supplements and powder :

https://www.amazon.com/s?k=D-mannose&ref=nb_sb_noss_2

All you need to do is mix the powder with water and drink it down or take the capsules, all per label directions.

Two other simple preventatives is to void as soon as the urge is felt so that the urine does not sit in the bladder longer than it has to in an environment that can be conducive to bacterial growth. The second preventative is the use of probiotics such as L. rhamnosus, L. reuteri and L. casei shirota.

Art

REPLY   28      



Deb C. (East Coast, Usa) on 11/24/2016
5 out of 5 stars

Who would have thought sugar would be be the cure for my constant UTI's? D-Mannose has made my life so much better. Every 2-3 months a UTI would flare up. It has gotten to the point where I can feel it start and know immediately what it is. I would go to the doctor to tell them. Hey! I don't need the lab tests. I know my body. They would roll their eyes. They need do the lab test anyway. The tech would call... Surprise! You do have a UTI.

After a while, the drugs and doctors visits were overwhelming. I found out of D-mannose on this site. It is a wonder! Now when I feel a UTI coming on, I take a couple doses of D-Mannose for a day or two and it is gone. I has changed my life for the better.

REPLY   8      

Sabrina (Houston) on 08/03/2016
5 out of 5 stars

After doing research I wanted something that would work fast because we all know how irritating a UTI can be. After coming on this site and reading about D-Mannose, I did further research and found out this is actually an effective remedy. I went to store and bought, although it's a bit pricey I didn't mind paying the price to heal myself. Once I took the first dose, I immediately felt some relief. I was taking cranberry pills also along with a probiotic. I highly recommend this and also uvi ursi also helps with UTI's. Hope this was helpful.
REPLY   6      

Carl (London) on 06/21/2016
5 out of 5 stars

I was in a car accident when I was young which left me wheelchair bound. This accident seems to have a negative effect on my bladder and I am prone to UTIs. I have tried many things but Dmannose seems to help the best. I have now moved on to d Mannose that have Cranberry and Hibiscus. They taste better so that's a big improvement but I feel that little bit more healthier.
REPLY   8      

Gg (Denver) on 03/02/2016
5 out of 5 stars

D-mannose works great for a UTI. If it doesn't, see a naturopath, acupuncturist etc to verify its nothing else. I had ecoli and it caused ongoing uti. my practitioner said female openings in proximity can cause these things to happen.
REPLY   3      

Julie (Nm) on 12/02/2015
5 out of 5 stars

Hi, D-Mannose powder is wonderful for recurring bladder infections. I have almost always had my urine screenings to come back from the lab with low grade infection but don't take antibiotics unless absolutely necessary. I began searching online for help with bladder infections and found that others had great results with D-Mannose. It seems that bacteria attach themselves to the bladder lining and D-Mannose creates a "slickness" to that lining which creates conditions in which the bacteria detach and you rid yourself of the bacteria via urination. Whatever the process, IT WORKS. I used D-Mannose once per day just before retiring to sleep for 10 days. I keep D-Mannose in my medicine cabinet but have not had to use it for more than six months now. WONDERFUL!! I hope this works for you.
REPLY   4      

Rebecca M. (Co) on 09/02/2015
5 out of 5 stars

A word on drinking tons of water--I've read that you should take d-mannose with about 4 ozs. of water so that your urine is not SO dilute that you pee it out quickly. It's ideal to take it when you wake up in the middle of the night, as it will have a chance to sit in your bladder for several hours and bind to the bacteria.

D-mannose was a game changer for me after years of recurrent UTIs!

REPLY   7      

Linda (Florida) on 04/25/2015
5 out of 5 stars

For anyone suffering from Urinary Tract Indections...

1st, they are caused from bacteria getting up into the urethra( the pee pee tube). When you have sex, always pee before and after because during sex, the bacteria get pushed up there.when you pee after, it pushes out the bacteria. A natural sugar found in Cranberries is called D-Mannose powder. Available at all health food stores.

If you have a UTI, take1 teaspoon every few hours for a day. Within 30-45 minutes of the first dose, the pain and fevers will be gone, and the burning. It is a miracle supplement! . It works by making the urethra walls slippery and so the bacteria can't hold on. It's so much easier and healthier than antibiotics. I take it an hour before I know I'm going to have sex with my boyfriend. Works to keep you free of urinary tract infections. Just look it up on the Internet to learn more about it. I like the powder better than the pills. The powder works faster!

REPLY   7      

next page
2 3 4