Art (California) on 08/03/2026

I'm glad you brought estrogen and testosterone up. If you check with AI, I think you will find that the PHL will tend to have a normalizing effect on estrogen and testosterone levels. Here is a little AI snippet on that topic :

Based on what we know about the biology of the components of the PHL, it is plausible that the PHL could help maintain or normalize sex hormone signaling in aging, but it is unlikely to substantially increase estrogen or testosterone levels directly. In the context of Alzheimer's disease (AD), that distinction is important because preserving hormone function and receptor responsiveness may matter as much as increasing hormone concentrations.

Art