Grapefruit Seed Extract for Sinus Infections

5 star (20) 
3 star (1) 
1 star (2) 

Paul (CA) on 05/17/2022:
5 out of 5 stars

Wow, thank you for sharing this. I just tried Grapefruit extract GSE in a neti pot with pink salt (finely ground) and it's definitely helping my sinuses!

I did 10 drops.

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Anne (Austin, TX) on 01/25/2022:
1 out of 5 stars

After doing extensive research in scientific papers, I am pretty certain that the observed effects of GSE are not due to it but to added synthetic microbicides. One of those was always present when GSE was analyzed, whereas no verifiably beneficial compounds could be found by simply analyzing extracts produced without those microbicides. More to the point, the specific synthetic microbicide present changed over time, with some falling out of favor over the past 25+ years.

Please read these statements by the American Botanical Council and see the studies:



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Art (California) on 06/10/2020:
5 out of 5 stars


One feature of long term sinusitis is that biofilms can form to protect whatever pathogen('s) are present. Xylitol has biofilm busting characteristics as does colloidal silver. There is a commercial sinus spray that contains xylitol called "Xlear" that I have bought and is available on amazon : I can use the colloidal silver (AgNPs) in a neti pot, but not at the same time as the Xlear because the saline portion of Xlear may cause the colloidal silver to break down if the colloidal silver is not capped. So, for myself, I might use Xlear in the morning and colloidal silver in a neti pot with 5% to 10% xylitol dissolved in the colloidal silver in the afternoon and then Xlear in the evening and repeat each day until the biofilms are destroyed and the pathogen('s) eradicated.

A third option I might also try for myself is to skip the Xlear and just use the colloidal silver + 5% to 10% xylitol in my neti pot as needed.In my experience, I have also found that the xylitol has helped to reduce the sting of 20 ppm colloidal silver from the neti pot and I only mix enough for one use at a time and do not store any of the mix unless I will be using it the same day that I made it.

Silver nanoparticles have biofilm busting qualities.

As long as the biofilm(s) are present, the pathogen's are fairly well protected and resistant to most attacks against them so breaking them down is important. Art

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Erkin (Germany) on 06/10/2020:
1 out of 5 stars

I bought grapefruit seed extract (one that is recommended in blogs in Germany) because of positive comments here and I am using it now for 1 week. I have a chronic sinusitis for around 20 years and I have been operated three times on my sinuses. Unluckily, I couldn't see any benefit of the grapefruit seed extract nor for my sinusitis neither for anything else. I drink it with water (20 drops in 1 glass 2 times per day). Since three days I use it also as nose spray. I mixed 10 drops in 20 ml water and spray it three times a day. But using it as nose spray irritated my nose and I feel more bad than before using it. I will stop using it.
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Sl (Ky, US) on 02/08/2015:
5 out of 5 stars

I have been using grapefruit seed extract 10 drops in 5 oz water plus 1 packet of a sugar alternative for sinus infection. It is a miracle! I do this 3 x day. Also using a nasal spray plus. So glad I found this works! Next time I think I can avoid Dr. visit.
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Heather (Santa Monica) on 04/16/2014:
5 out of 5 stars

Yep, grapefruit seed extract is my go to remedy for sinus infections. I've tried in my neti pot, but it's too strong. I usually take GFSE drops internally (about 10 drops 3 times a day) but also use sea salt and peroxide in my neti pot to irrigate the sinuses.
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Randall (Sioux City, Iowa) on 10/31/2012:
5 out of 5 stars

FOUR MONTHS OF SINUSITIS! TOTALLY MISERABLE! Two rounds(10 days each) of amoxicillin. Nothing. Still having one nostril closed off almost 24/7 and the other half open. Sleep was almost impossible and I was just miserable. I started to Google to find any other way to help. Warm compresses, hot showers, and more antibiotics.

Then I saw GSE. Ordered it and that was the miracle that I was looking for. Took a 2 ounce nasal spray bottle left over(couldn't live without the over the counter spray that at the end only kept my nose open for less than a hour)cleaned it out and put 2 ounces of saline solution and 3 drops of GSE in it. DAY ONE: Took eight ounces of orange juice with 15 drops of GSE concentrate three time a day(45 drops a day total). I then sprayed my homemade GSE nasal mix in my nose 4 times a day with 2 sprays in each nostril each time. By morning two I stared to blow my nose and sorry this may sound gross but the green/yellow mucus was thinning and turning clear. I could not believe it! I woke up with only a small headache for the first time in months and I could breath a little better.

DAY THREE: UNBELIEVABLE! I could breath out of both nostrils! Not completely but well over 50% better! Pressure and pain was less than half. All the antibiotics and hot showers for the last 4 months had done nothing close to the 2 full days of GSE. To make my story short and happy within 6 days of continuing the GSE treatment I was cured! YES CURED! People say that GSE only works because it has some synthetic stuff in it. Why do I care. IT WORKS and no side effects! And the cost is crazy! CHEAP! CHEAP! CHEAP! I will never be without it. I will always keep in touch with my Dr. But GSE will almost always be my first course of action for any cold or sinus problems! You have to try it. IT WORKS MIRACLES!

REPLY   28      

Rachel W (San Francisco, Ca, Usa) on 09/18/2012:
3 out of 5 stars

Better But With Side Effects

I get severe sinus infections at least once a year, either from seasonal changes or developing it when I catch a mild cold from someone.

This time I had a small cough that lasted a week before the infection progressed to my nose (just in time for work on Monday, ugh).

I've previously used saline solution with my neti pot with some success, but only if I do it early enough. When my sinuses get worse it only irritates it even more and causes more swelling. Even Apple Cider Vinegar has only temporary effects on me.

A friend recommended GSE in my netipot and voila! Instant results with just a couple drops of it in the water. It completely drained my nose! It was expensive but very well worth it. It's my first day using it but I plan on doing it every day until it goes away. I'm also adding it to my water to drink. I did notice that my sense of smell/taste were completely gone, which I'm hoping is only temorary until my sinuses are normal again. However, I'd much rather try this than any over the counter colored chemicals that make me drowsy!

REPLY   6      

Mlove (Honolulu, Hi) on 07/17/2012:
5 out of 5 stars

I just wanted to say that I have been taking grapefruit extract in tablet form for years whenever I get a cold or sinus infection. I take 2 little tablets three times a day for about a week and on the third day, I always feel better. Colds do not go into sinus infections if I take it and if I do get a sinus infection (like I did recently from swimming in the ocean), it goes away within a couple of days when I take the tablets. If I don't tke them, I stay miserable. I had a naturalpathic doctor tell me it was okay to take them for as long as a month at a time, but I never need to. They always make me feel better, so I take them anytime I feel a little under the weather and it always works. My husband does the same thing and it works for him too. The tablets are small and easy to get down. No bad side effects for us, only good effects.

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Sarah (Lebanon, Nh) on 06/27/2012:
5 out of 5 stars

I was diagnosed with nasal polyps a month ago. I had chronic sinusitis (not a runny nose, just often stuffed up and a poor sense of smell) which never really bothered me until one of my nostrils became constatntly plugged. First let me say that there is a lot of scary stuff on the internet when you're looking for health information. Sure this condition is annoying, but life is still pretty good!

I went to the ENT, was diagnosed, and he gave me 2 weeks of prednisone, and an antibiotic. Steroids are terrible for you, but they also shrunk the polyp and brought back my breathing, and sense of smell! All the while I wondered what would happen to my nose once I was off the steroids.

By the time I was done with prednisone my nose was not 100%, but it was much improved. My constantly plugged nostril was now open 60% of the time. I then started a steroid nose spray (which supposedly have fewer side effects) to keep things open.

Things seemed pretty stable for a week, and I decided to try some of the homeopathic remedies to see what effects they had. I got really brave, and put two little drops of GSE into my neti pot.

I did my third GSE neti wash tonight, and it seems to be making a difference! My "bad" nostril is open almost all of the time now, and still seems to be on the upswing. I will say this - the GSE certainly isn't hurting anything, and I distinctly feel that it is improving my condition.

I'll write more if anything drastically changes. I got an allergy test which came back totally negative, so what's causing the inflammation in my nose is sort of a mystery. I guess the theory with GSE is that if I have a low level fungal infection, or perhaps an over reaction to normal fungus in the air, the GSE and its potent antifungal properties helps reduce my inflammation. Hmm. as of now, I think I buy it.

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