Pulmonary fibrosis is a progressive lung disease marked by scar tissue formation that reduces lung capacity and oxygen exchange. While conventional treatments include medications and lung transplants, many people are exploring natural remedies to support lung health, reduce inflammation, and potentially slow disease progression.
This article highlights research-backed natural compounds like NAC, serrapeptase, bromelain, nattokinase, and papain, along with herbal strategies and other alternative approaches that may benefit individuals with idiopathic pulmonary fibrosis (IPF).
NAC is a powerful antioxidant and a precursor to glutathione, the body’s master detoxifier. It has shown promise in reducing oxidative stress and thinning mucus in the lungs—key factors in pulmonary fibrosis. NAC may ease cough, improve breathing, and support overall lung function.
Suggested use: 600–1,200 mg daily, in divided doses. Consult with a physician before use, especially if taking medications.
Several proteolytic enzymes have demonstrated potential in reducing scar tissue and inflammation in the lungs. Below are four key enzymes studied for IPF:
Serrapeptase is a proteolytic enzyme derived from the Serratia bacteria found in silkworms. It breaks down non-living tissue such as mucus, scar tissue, and fibrin without harming healthy cells.
In a mouse model study, serrapeptase reduced lung fibrosis and inflammation and improved breathing. A review in the Journal of Pharmacopuncture also highlighted its potential as a supportive therapy for respiratory diseases, including IPF.
Bromelain is an enzyme extracted from pineapple stems, known for its anti-inflammatory and immune-modulating effects. It may help reduce lung scarring and inflammation.
In one study, bromelain reduced fibrosis and lung inflammation in mice with pulmonary fibrosis, suggesting potential therapeutic value.
Nattokinase is an enzyme derived from fermented soybeans and known for its fibrinolytic properties, helping to dissolve blood clots and fibrin.
A study in the Journal of Natural Medicines found that nattokinase significantly reduced lung fibrosis and improved respiratory function in animal models.
Papain, a proteolytic enzyme from papaya, has been shown to reduce inflammation and dissolve protein-based scar tissue. In a Respiratory Research study, papain reduced lung inflammation and fibrosis in a pulmonary fibrosis mouse model.
Hydrogen peroxide inhalation is a home remedy used by some individuals with chronic lung conditions. It involves inhaling a highly diluted 3% hydrogen peroxide mist through a nasal spray pump aimed at the throat.
This method is believed to help break down mucus and improve oxygenation. However, caution is essential. Only 3% food-grade hydrogen peroxide should be used, and proper dilution and usage should be confirmed with a healthcare provider.
Herbs with anti-inflammatory, expectorant, and immune-boosting properties may offer additional support for lung health:
These herbs can be consumed as teas, tinctures, or supplements. As always, check with your doctor before starting herbal remedies, especially if you're on medications.
Pulmonary fibrosis remains a difficult condition, but emerging research on natural therapies like NAC and proteolytic enzymes offers hope for symptom relief and improved quality of life. These approaches may complement conventional treatments and support overall lung health.
Continue reading below to see which supplements and natural remedies have helped Earth Clinic readers manage pulmonary fibrosis—and share your experience with us!
