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Acetyl-L-Carnitine for Peripheral Neuropathy

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The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.

Gord235 (Vancouver, British Columbia) on 01/01/2018:
5 out of 5 stars

Update:

Since my last post I have learned that taking antibiotics can lower B12 levels and that a B12 insufficiency can be the cause of peripheral neuropathy in up to 7% of cases. I had surgery recently and was on antibiotics for two weeks. This may account for the dramatic improvement I experienced once I started taking a B12 supplement.

As a result of this new information I have returned to my regimen of taking B1- 2X100mg/daily, B6 - 2X100mg/daily, B12 - 2X5000mcg/daily as well as ALA - 4X200mg/daily and Serrapeptase - 10X120,000SU/daily. Although not completely rid of symptoms the frequency and intensity of pain has been reduced by 90%. I anticipate that I will eventually be able to reduce the number of things I am taking but feel certain that the B12 will be the last thing to go as it has been the only thing to give me overnight relief. I wish everyone well on their search for a cure.

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Gord235 (Vancouver, British Columbia) on 10/10/2017:
5 out of 5 stars

Update: I have been able to cut back on the B vitamins (1,6 and 50 complex) although I still take 2 X B12 5000mcg/day. I have increased the ALA (r+alpha lipoic acid) to 800mg/day as it seems to be helping the most.

I also take N-Acetyl-L-Carnite 1500mg/day and Calcium/Magnesium 2X 133/167mg/day.

This protocol has eliminated 90% of the pain and I believe it is the ALA that is helping the most. Best wishes and good luck to all in their search for relief.

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Brad (Owensboro, Ky) on 01/14/2012:
4 out of 5 stars

I am not saying anything conclusive yet, but I have been taking Acetyl-l-carnitine for three days. I had numbness, tingling and sometimes burning in my feet. I have been taking 800mg daily. After three day they feel remarkably better. I will post further as time goes on.

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Mike (New York City, New York) on 02/09/2009:
4 out of 5 stars

I have been taking Acetyl-L-Carnetine for a couple years to combat my peripheral neuropathy. It has been recommended by a neurologist in New York. My feet are progressively doing worse but I don't know how much worse they would be without it. I also take Alpha Lypoic Acid. I take about 3000mg of Acetyl-L-Carnetine a day. I am looking for whatever works. I have the neuropathy through anti-hiv meds and possible from the virus itself.
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