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Magnesium for Depression


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Cynthia (Madison, WI) on 04/11/2025
5 out of 5 stars

Magnesium has been a life saver to me for depression. I read an article on Pub Med about a study where Japanese women were given 500 mg of magnesium chloride twice a day, and their depressive symptoms greatly improved. I decided to give it a try.

Well, I can report it works, and works really well! Most days, just 500 mg of magnesium chloride gives me the lift and joy back in my life. I am noticeably upbeat, I want to sing, I want to do things and am more likely to get out of the house, I have a smile on my face. I feel so much better! I think that many other good forms of magnesium would have the same effect.


REPLY   3      

Doris (Murfreesboro, TN) on 12/05/2007
5 out of 5 stars

My son suffered from anxiety and depression after his divorce. I read an article by George Eby about Magnesium Glycinate for depression. I bought my son some of the magnesium and after a few days he started feeling better and talked about having more energy and concentration. He took 800-1000 mgs. for a few days to build it up in his system, then backed down to 400 mgs. The Magnesium Glycinate really changed his life.
REPLY   1      

Art (California ) on 09/10/2017
5 out of 5 stars

Many people have reported the benefits of magnesium chloride oil applied topically here on EC, but magnesium chloride tablets are also well absorbed and according to the recent study link below, at the proper dose can have a significant impact on depression in people. This is important because many of the side effects from prescription antidepressants can be hard to deal with and even unhealthful, so alternatives like magnesium chloride tablets which are more likely to have healthful side effects are very useful in the treatment of depression.

This study is very helpful because it not only shows that mag chloride tablets are useful for depression, but it is also well tolerated with a very good safety profile. This study is also useful because it shows the dosing used and describes the benefit achieved. According to the study, some participants started to see benefit after just two weeks of supplementing. Participants of the treatment group took 4 tablets of magnesium chloride per day. This is the manufacturer who supplied the magnesium chloride tablets and the tablets are similar to those used in the study, but possibly 20mg more per tablet.

https://www.amazon.com/Alta-Health-Magnesium-Chloride-200/dp/B00IX05914/ref=sr_1_3_a_it?ie=UTF8&qid=1505075869&sr=8-3&keywords=alta+health+magnesium+chloride

As you can see from the study they used four tablets of Alta Health Magnesium Chloride at 500mg per tablet for a total of 248 mg of elemental magnesium per day. Magnesium chloride is well absorbed topically or orally. The tablets seem relatively easy to take compared to mag oil application to the skin everyday.

Here is a link to the full study:

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180067

One important finding from the study is that some people may be able to get by with a smaller dose than what was used in this study.

Art

REPLY   12      


Leah (Israel) on 09/01/2013
5 out of 5 stars

I have a relative who was so depressed, he tried to hurt himself badly. I had read that magnesium is amazing for depression and works rather quickly. I convinced him to try it. One tablet each day of the daily recommended dosage and he was unbelievably back to his old happy self in two days! However, when he forgets to take this, he sinks back into depression very quickly.

I truly truly believe that depression is a chemical imbalance and not necessarily a psychological problem. I really hope this helps others out there who are suffering with this!

REPLY   2      

Celia (Seattle, Wa) on 08/18/2011
5 out of 5 stars

I would like to share my wonderful discovery of the power of simple magnesium to alleviate depression. I had been taking a powdered form of magnesium every night before bed, which made me feel Calm and relaxed. Then I stopped taking it. I began to suffer a lot of mood problems when stopping it, and when I resumed the powdered magnesium citrate, I couldn't believe how much better I felt the next day.

I also use a combination herbal therapy for Mood Support, which works well. And every day I take vitamin D at 4000 mg, fish oil, and something called lithium orotate, a safe, commonly found supplement for brain and mood health. (Don't let the word lithium scare you. Unlike the drug lithium, lithium orotate is safe to take and you don't need to have your blood tested. Please look up lithium orotate online for more info.)

But to me, the most important missing link in the puzzle was magnesium. You can buy it at the drugstore, but I do suggest taking at least 700 mg a day to begin to see results. I stagger the dose, taking 200 mg magnesium citrate tablets twice a day at work, and then taking the wonderful fizzy magnesium drink at night as a hot tea, which makes me feel very sleepy and Calm.

REPLY   2      

Jennifer (Chicago, Il) on 10/09/2009
5 out of 5 stars

Feeling extremely depressed, anxious, panicky, I first stsrted taking Magenesium Glycinate, which I thought worked well until I ran out read a little more about different types of Magnesium and went to my local health food store and bought Magnesium Citrate, 200 mg. I started taking 400 mg. in the morning and 400 mg. at night before I go to bed and I can't believe how much better I sleep on Magnesium Citrate! I just wanted to highly recommend it for depression and/or anxiety, it seems to relax your body and take you in to a deep sleep throughout the night.
REPLY   3      

Doris (Murfreesboro, TN) on 12/05/2007
5 out of 5 stars

My son suffered from anxiety and depression after his divorce. I read an article by George Eby about Magnesium Glycinate for depression. I bought my son some of the magnesium and after a few days he started feeling better and talked about having more energy and concentration. He took 800-1000 mgs. for a few days to build it up in his system, then backed down to 400 mgs. The Magnesium Glycinate really changed his life.
REPLY   3