I have DDD and have it mostly controlled now with boswellia and stopain roll on. But recently I started having extreme knee pain that radiates down my lower legs and feet. Its getting so bad that I can hardly walk or sleep! I have increased my vitamin C to 7 grams, take melatonin, acv, B complex, magnesium glycinate, zinc, black strap molasses, CS, NAC. I'm 68 years old. I've researched on here what to do, but can't find anything different than what I am already doing. I've tried daily vibration therapy for about a year. I have red light therapy that I'm using (but it's not helping). I need relief without turning to prednisone. Any ideas?
Replied by Art (California) on 06/29/2023
Hollyhock, These are others you might consider :
https://www.earthclinic.com/cures/ddd-art-solbrig.html
https://www.earthclinic.com/remedies/borax.html
And Berberine as discussed in the following :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414164/
Here is a relevant study quote :
' The results showed that BBR attenuated the upregulation of ECM-catabolic factors [matrix metalloproteinase (MMP)-3, MMP-13, a disintegrin and metalloproteinase with thrombospondin motif (ADAMTS)-4 and ADAMTS-5], and the downregulation of ECM-anabolic factors (type II collagen and aggrecan) following stimulation of the human NP cells with IL-1β. Treatment with BBR also protected human NP cells from IL-1β-induced apoptosis, as determined by western blotting and flow cytometry. Mechanistically, the IL-1β-stimulated degradation of IκBα, and the phosphorylation and translocation of nuclear factor (NF)-κB p65 were found to be attenuated by BBR, indicating that NF-κB pathway activation was suppressed by BBR in the IL-1β-treated human NP cells. The results of the experiments revealed a therapeutic potential of BBR for the prevention or treatment of IDD. '
Art
Replied by Hollyhock (America ) on 06/29/2023
Hi Art,
I forgot to mention I take borax daily for the past 3 years. I put 1/8 teaspoon in my bottle of water and sip throughout the day. So are you saying berberine will help this leg pain?