Posted By Cecilia (Liège, Belgium) on 01/20/2024

I've been diagnozed with severe osteoporosis, from genetical cause.

Moreover, I'm intolérant to gluten and milk. What doesn't help for calcium.

My doctor asked me to take biphosphonate; my dentist didn't quite agree. My doctor prescribed me EVISTA but my body refused it : nauséas, headaches.

I take Vit D 3000 IE /day,

Magnesium glycerophosphte 300 +magnesium citrate 300 mg, and Vit B complex/day. Calcium 600 mgr/d. Horsetail 400 mg/day. My thyroïd is a bit too low but my parathyroid is OK.

Apparently, it's not enough, since my osteoporosis is still severe.

I don't like to take calcium, a have a kidney's problem and must treat him at the same time (via homeopathy and budextract). I must say that I follow this treatment only since 2 years, because I felt very lonely to search natural remedies, quantities etc.

Replied by Cecilia (Liège. Belgium) on 01/22/2024

Art, this is my second replay to your post.

I'm suffering a leaky gut and I'm convinced that there is a connection with osteoporosis.

What 's your opinion?

If you agree, how heal both?

Asame? Separately?

Are some remedies effective for both of them?

I'm 77 and sufferings come one after one.

Thanks . I wish you the best.

Replied by Cecilia (Liège Belgium ) on 01/22/2024

Hello, Norma.

I'm 77 years old and suffer severe osteoporosis: -2.3 and - 3.3. My body refuses the current remedies my therapist prescribed me: Phosphonates and, after, Evista.

And no, there ain't no session like you recommended.

I'll follow the natural treatment Art gives me. Let's hope for the best

Have a nice day.

Replied by Stella (Jones) on 01/22/2024

I am 55, my femoral neck: T score -3.6, Z score - 2.4; Total hip: T score - 3.3, Z score - 2.4; AP L Spine: T score -3.6, Z score - 2.3

Since nothing could be done to reverse osteoporosis, I concentrate on fall prevention and improving balance-special exercises.

I take daily a "Bone Health" supplement, not sold retail, 2 caps serving size includes:

D3 25 mg, K2 98mcg, Calcium (calcium citrate 20%) 124mg, Magnesium Glyconate - 30mg, Proprietary blend: Ipriflavone, Betaine HCL, Bromelain, L-Glutamine, Papaian fruit, Rose hips extract 4:1, Horsetail extract 4:1, Boron Citrate 5%, Parathyroid(Bovine).

In addition I take once a week 10,000 D3 plus Full spectrum K2(Innovix Lab) plus Tetra- Boron 3mg

I used to take Garden of Life Bone restore supplement, but it was purchased by Nestle, so I stopped.

I also use Joovv, full size panel, red light therapy daily on my entire body.

As soon as sunlight reaches frequencies that stimulate vitamin D production I'd get sun exposure early am and 15min mid day- full body exposed. Luckily I live at 26°9′N .

Replied by Art (California) on 01/22/2024

Hi Cecilia,

I agree with you.

If you are suffering from leaky gut, then you have gut dysbiosis which causes inflammation which increases harmful bacteria in the gut which increases inflammation and bone loss and ultimately osteoporosis as discussed in the following December 2023 report :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10676803/#:~:text=We have also demonstrated that, bone loss, perhaps promoting osteoporosis.

Here is a relevant quote from the report that seems to cover what you are describing :

' We have synthesized the evidence that gut bacteria regulate immune cells and inflammation responses by influencing cell signaling proteins and immune cell activity with bacterial metabolites. We have also demonstrated that these mechanisms are related to bone physiology and remodeling. Therefore, since our gut bacteria maintain anti-inflammatory processes, dysbiosis and loss of diversity could remove these anti-inflammatory processes and induce bone loss, perhaps promoting osteoporosis. '

The simplest answer to heal both issues is to have a fecal microbiome transplantation (FMT) that is highly likely to alleviate both. This is a process where you take a feces sample from a tested and proven healthy donor and transplant it into your digestive system in order to positively alter your gut microbiome and rebalance your gut microbiome toward healthier bacteria dominance to alleviate your current health issues. The following review article explains how FMT can affect osteoporosis and it is already proven in multiple other studies that FMT can repair gut dysbiosis :

https://link.springer.com/article/10.1007/s00774-022-01375-x#:~:text=Notably, these studies provide the, mass and prevent the osteoporosis.

Here is a relevant quote from the review :

' Herein, based on the gut/bone axis and proven regulatory effects and gut microbiota on osteoporosis, this review expounds relevant basic researches and clinical practices of FMT on osteoporosis, thus demonstrating the potentials of FMT as a therapeutic option for osteoporosis and further providing certain reference for the future researches. '

So while FMT is already in use in many countries, here in the USA, it is only allowed for two health conditions clostridium difficile (C diff.) and IBS that have proven refractory to standard medical treatment. In certain other parts of the world it can be used for multiple other conditions. So if you happen to be in an area of the world that might allow treatment for gut microbiome dysbiosis or osteoporosis, it could be your solution. I have written about FMT and its many uses as well as the multiple ways it can be applied to humans here :

https://www.earthclinic.com/remedies/fecal-microbiota-transplantation-exploration.html

Art

Replied by Art (California) on 01/22/2024

Hi Cecilia,

I am not a big fan of calcium supplementation and in your case especially with kidney dysfunction, however some calcium is needed. One of my main concerns with calcium supplements is they generally come in large doses which I don't think the body handles well. Ideally, I think they would be more tolerable if available in doses such as you might get from food that the body definitely knows how to handle. If your issue with dairy is lactose intolerance, you can consider a supplement such as this to make dairy tolerable for you :

https://www.lactolerance.fr/en/5-lactolerance-4500#:~:text=A daily capsule of Lactolérance, immediately, from the first use.

If that is not doable for you then you can consider other foods beside dairy to get calcium such as broccoli, sardines, seeds such as pumpkin, chia or celery seeds, pistachios, lentils, almonds, collard greens, kale, rhubarb, hazelnuts, edamame, tofu and figs.

Also keep in mind that in order to make the most of the calcium you are getting, you will need cofactors such as magnesium, vitamin D, vitamin K2M7 and boron all of which will be useful for osteoporosis.

I am of the belief that calcium is absolutely necessary for humans being the most abundant mineral in the body. I have never heard or read of anyone saying that calcium is not needed and I believe that to be incorrect and unhealthful information to say that! I think for the majority of senior citizens, they can get enough calcium from food intake, there may be people who require extra calcium intake for various reasons, but I would like to see such intake in low doses that are comparable to what you might get from food so that the body is better able to utilize it just as it would had you gotten it from food.

I agree, it sounds like a new therapist /doctor is in order for you! Ask her to tell you what the known side effects and adverse events are for bisphosphonates.

Here is a list of them :

https://www.drugs.com/sfx/fosamax-side-effects.html#serious-side-effects

More common

• Stomach pain

Less common

• Difficulty with swallowing
• heartburn
• irritation or pain of the esophagus
• muscle pain

Rare

• Skin rash

Incidence not known

• Blistering, peeling, or loosening of the skin
• bloating or swelling of the face, arms, hands, lower legs, or feet
• bone, joint, or muscle pain, severe and occasionally incapacitating
• chest pain
• chills
• confusion
• convulsions
• cough
• diarrhea
• difficulty with breathing
• difficulty with moving
• heartburn
• heavy jaw feeling
• hives or welts
• irregular heartbeats
• itching
• joint pain
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• loosening of a tooth
• muscle aching or cramping
• muscle cramps in the hands, arms, feet, legs, or face
• numbness and tingling around the mouth, fingertips, or feet
• pain or burning in the throat
• pain, swelling, or numbness in the mouth or jaw
• rapid weight gain
• red skin lesions, often with a purple center
• red, irritated eyes
• redness of the skin
• sore throat
• sores, ulcers, or white spots on the lips or tongue or inside the mouth
• stomach cramps
• swollen joints
• tingling of the hands or feet
• tremor
• trouble breathing
• unusual tiredness or weakness
• unusual weight gain or loss
• vomiting

Other side effects of Fosamax

Some side effects of alendronate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Constipation
• diarrhea
• full or bloated feeling
• gas
• headache
• nausea

Incidence not known

• Blurred vision or other change in vision
• dizziness or lightheadedness
• eye pain
• feeling of constant movement of self or surroundings
• general feeling of discomfort or illness
• hair loss or thinning of the hair
• sensation of spinning
• sensitivity of the eye to light
• tearing

For Healthcare Professionals

Applies to alendronate: oral solution, oral tablet, oral tablet effervescent.

General

Generally, this drug has been well tolerated. Adverse effects usually have been mild when patients adhered to prescribing instructions.^[Ref]

Musculoskeletal

Very common (10% or more): Bone, muscle or joint pain (sometimes severe)

Common (1% to 10%): Muscle cramp, joint swelling

Rare (less than 0.1%): Osteonecrosis of the jaw, atypical subtrochanteric and diaphyseal femoral fractures

Postmarketing reports: Myalgia, low-energy femoral shaft and subtrochanteric fractures^[Ref]

Dermatologic

Common (1% to 10%): Alopecia, pruritus

Uncommon (0.1% to 1%): Rash, erythema

Rare (less than 0.1%): Rash with photosensitivity, severe skin reactions including Stevens-Johnson syndrome and toxic epidermal necrolysis^[Ref]

Gastrointestinal

Common (1% to 10%): Abdominal pain, dyspepsia, acid regurgitation, nausea, abdominal distension, constipation, diarrhea, flatulence, esophageal ulcer, gastritis, gastroesophageal reflux

Uncommon (0.1% to 1%): Gastric ulcer, esophagitis, esophageal erosions, melena, dysphagia, vomiting

Rare (less than 0.1%): Esophageal stricture, oropharyngeal ulceration, upper gastrointestinal PUB (perforation, ulcers, bleeding)

Postmarketing reports: Localized osteonecrosis of the jaw, generally associated with tooth extraction and/or local infection with delayed healing^[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness

Uncommon (0.1% to 1%): Dysgeusia^[Ref]

Other

Common (1% to 10%): Vertigo, asthenia, peripheral edema

Uncommon (0.1% to 1%): Transient symptoms of myalgia, malaise and rarely, typically in association with initiation of treatment^[Ref]

Ocular

Uncommon (0.1% to 1%): Eye inflammation (uveitis, scleritis, episcleritis)^[Ref]

Metabolic

Rare (less than 0.1%): Symptomatic hypocalcemia (often in association with predisposing conditions)^[Ref]

Hypersensitivity

Rare (less than 0.1%): Urticaria, angioedema^[Ref]

Respiratory

Postmarketing reports: Acute asthma exacerbations^[Ref]

I'm not sure how a doctor can just prescribe such a drug to their patients.

Art

Replied by Cecilia (Liège Belgium) on 02/01/2024

Art, so many, many thanks for your response. Finally, I get a response, the FMT, that includes many diseases I endure. I've always thought they were linked but the doctors, behalf one, treated only a part of my body and refused to consider it as a whole. Of course FMT will no be easy to realize but I'm a perseverant person. Moreover, I'm encouraged by the list of deseases tested : five of mines are in. Linked, I'm sure of it since years, but never found a therapist like you to listen to me and believe me. Be blessed, dear Art. I hope, in a few months, be able to inform you that I'm no longer living an under-life.

Cecilia

Replied by Art (California) on 02/01/2024

Hi Cecilia,

I hope you are able to get the FMT and if so, I hope you come back and let us know you how you do.

Art

Back to Osteoporosis Q&A