Replied by Art (California) on 05/26/2021
Jay,
Inflammation and excess oxidative stress can cause edema/swelling. Melatonin has shown to reduce both issues in studies.
You may find these articles useful:
https://pubmed.ncbi.nlm.nih.gov/33636209/
https://pubmed.ncbi.nlm.nih.gov/33962019/
https://pubmed.ncbi.nlm.nih.gov/33517190/
https://pubmed.ncbi.nlm.nih.gov/33432588/
Melatonin has a very good safety profile :
https://link.springer.com/article/10.1007/s40261-015-0368-5
You can also consider a B vitamin complex such as B-150 for its protective effects, which your doctor may have already recommended.
You can use these studies to discuss very high dose melatonin use with your doctor because you have a lot at stake here and the sooner you try to reverse the process, the better.
Art