Replied by Ted (Bangkok, Thailand)

While the condition can have several causes, your condition based on your feedback may not be a fungus or yeast otherwise it would have responded to the hydrogen peroxide 1% or the saturated borax in hydrogen peroxide 1%, at least initially. Hence the other cause may either be bacteria, mineral and vitamin deficiency or hormonal problems. Magnesium, manganese, iodine and vitamin C is one possibility.

But it would seem that I would need to consider whether there is any other mineral uptake from supplements. The only way to be sure, is to chew on the mineral supplements. A copper chloride weak solution (which means a copper chloride less 1% dissolved in 99% water) applied to the scalp would be an antifungal and react with the body's protein to become a copper peptide.

An interesting healing of the scalp may be possible with even an aloe vera (high concentration) applied topically. The active substance of aloe vera I suspect is the allantoin that allows some scalp to recover.

The real hair losses and the conditions you mentioned, does not appear to be a generic seborrheic dermatitis, and hence the problems of the treatment.

It appears to be an Accutane that causes sebeorrheic dermatitis which is why the scalp is so unresponsive to many treatments. Would be nice if you have mentioned to me earlier that the Accutane and Rogaine (or Regaine) was causing the seborrheic hair loss condition. It helps to know the cause. Your cause, in my opinion is a bacteria and Accutane, with possible mineral deficiencies, namely zinc. The reason is that Accutane was designed to kill the bacteria and kill off the body's sebum (which naturally would cause hair loss). Too much or no sebum, either way is related to hair growth since sebum works together with the hair or at least found along with it.

Furthermore, I would look and examine how Accutane and Rogaine caused the hair loss in the first place. The ingredients of accutane is the isoretinoin.

The active ingredients of accutane listed is isoretinoin and the problem inactive ingredients that I worry about is BHA (not BHT), hydrogenated oils, and iron oxide food coloring. I isoretinoin to be a dangerous chemical that induces oxidative DNA damage, and there are literature to say that since it causes birth defects too.

The reason why isoretinion works is it works by killing off the sebum, reducing its production and killing off the acne. The problem about this is it causes extreme scalp drying and kill off the sebum, you kill the hair too since the hair needs sebum, without which to lubricate would cause hair to dry or can no longer form. Isoretinoin also causes the body to go into hyperlipidemia, please see research abstract below. That is because once the sebum is destroyed (just my opinion), the body has no way of getting rid of the oils, so it increases inside the body which leads to oil rancidity, such as oxidation of isoretinoin and other oils, which is toxic to the body, but might be food for the bacteria, which leads to more hair losses.

Therefore, there is two possible addition to reduce this problem namely one tablespoon of granulated lecithin taken two times a day, vitamin E 400 i.u. a day, and if it is not working out 250-500 mg every other day of BHT supplements, to reduce the oxidative effects of the oils. The other oils that need to reduce is the triglycerides and free fatty acids. Therefore 1000-3000 mg of trimethylglycine and glycine may be helpful also. If liver is effected due to hyperlipidemia than 500 mg of N Acetyl Cysteine. The glycine reduces free fatty acids. Methylated glycine may also be more useful, but if cannot be obtained than glycine would do. Lecithin by the way is a fat emulsifiers, and reduces the body's hyperlipidemia.

As to the damaged DNA, little can be done if it is damaged except to provide the supplements for DNA repair. Lacking time right now, I would consider brwer's yeast, since it is rich in RNA/DNA, usually 1000-3000 mg.

P.S.

As a side note, high fatty foods and sugar should be avoided altogether. It may worsen the condition except only occasional supplements of evening primrose oil and fish oil (such as twice weekly), 500 mg for example. Vitamin Complex will help some of the sugar problems as well as lecithin by reducing some fatty buildup in the liver. "

Isotretinoin and serum lipids: studies on fatty acid, apolipoprotein and intermediary metabolism M.F. LAKER*, C. GREEN1, A.K.M.J. BHUIYAN* AND S. SHUSTER1

1Department of Dermatology, University of Newcastle upon Tyne, U.K.*Department of Clinical Biochemistry and Metabolic Medicine, University of Newcastle upon Tyne, U.K. Dr M.F.Laker, Department of Clinical Biochemistry, University of Newcastle upon Tyne, Newcastle upon Tyne NE2 4HH, U.K. SUMMARY

Thirteen patients with severe acne were treated for 16 weeks with 1 0 mg/kg/day isotretinoin. There were significant increases in serum cholesterol (P < 0 02), triglycerides (P < 0 02) and apolipoprotein B (P < 0 02). No changes were found in serum apolipoprotein A-1, non-esterified fatty acids (NEFA), carnitine, lactate, pyruvate, glycerol, alanine, beta-hydroxy-butyrate, glucose or insulin.

We therefore found no evidence that the hyperlipidaemia of isotretinoin therapy is due to increased fluxes of NEFA from adipose tissue to the liver, although we cannot exclude the possibility that there are changes in the proportion of NEFA being esterified to triglyceride or undergoing beta-oxidation. We suggest that the hyperlipidaemia induced by isotretinoin may be due to an increase in circulating lipoprotein from increased production or impaired catabolism.