I have been keeping track of what friends and the EC community are telling me that melatonin lotion has helped them, and that list has been growing steadily to 40 items. I will list those items below. What has become clear from these reports is that when it comes to pain relief, melatonin lotion is far superior to oral melatonin, even at oral dosing as high as 360 mg of melatonin per day. This brings me to the conclusion that a combination of oral melatonin in conjunction with topical melatonin is better than either one alone. It also brings up another important point I want to discuss with you.
One drawback to oral melatonin is that it has very poor bioavailability, and only about 3% of your oral dose actually becomes bioavailable as discussed here :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759723/
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