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JoJean (La Grande, OR) on 02/23/2007:
I also take MSM, however, if you read the literature...it tells you not to take it after 2 pm as it may cause sleeplessness. I have never experienced anxiety. I take 4 100 mg caps in the morning and 4 at noon with no problems. It does help my arthritis and my hair and nails grow like crazy.