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Ted (Bangkok, Thailand) on 02/01/2010:
Fluoride 1981; 14(1):21-29
Boron as antidote to fluoride: effect on bones and claws in subacute intoxication of rabbits
Elsair J, Merad R, Denine R, Azzouz M, Khelfat K, Hamrour M, Alamir B, Benali S, Reggabi M
Laboratories of Physiology, Toxicology and Galenic Pharmacy, Medical Institute, Algiers, Algeria
Summary: Rabbits were "subacutely" intoxicated by administration of 30 mg/kg/day of fluoride for 3 months followed by 15 mg/kg/day for a subsequent 3 months (F). Boron was given alone (B) as preventive and simultaneously with fluoride prophylactically (F + Bp), as well as therapeutically namely midway during the experimental period (F + Bpc) while fluoride was being administered and after it was discontinued (Bc compared with fluoirde interuption F*), at a constant F/B ratio. All groups were compared to normal controls.
Boron administered during fluoride intoxication or after its interruption, reduces fluoremia and increases urinary fluoride excretion. Skeletal fluoride levels are directly relatd to those of claws. They bear no relationship to fluoride in hair. The high fluoride content in bone in lot F decreases with addition of boron. It is still high in lot F* but returns to normal in loc Bc. Calcium content of bones remains normal in all lots. Posterior pad radiography shows a cortical thickness in lot F which is less pronounced in lots F + Bpc and F*, and returns to normal in lot Bc.
If a person were to take very high amounts of fluoride, then you need a combination of other remedies including tamarind, and grinded seeds of tamarind, which is also used to detox fluoride in the environment, especially the tamarind seed powder, or possibly tamarind seed extract. Unfortunately tamarind is a food and is not a required mineral as in boron, so it's considered a fruit, but can also be used to remove fluoride. Tamarind is a common candy in Thailand and is easily available here and is used in preparing various food delicacy here in Thailand also. It's not possible to prove the chelation of fluoride per se, but researchers assume they do, and from a practical point of view, as a consumer, it reduces fluoride toxicity and subacute doses, and that I find it just fine for most applications.