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Deanna (Michigan, US) on 08/07/2014:
My recent physical and blood tests, with a new doctor, showed great improvement in hormone levels and the pap smear came back showing not as much menopausal cellular changes. Some states require a prescription for the compounded suppositories and some do not. You will have to check in your area with a compounding pharmacy to see what the laws are. There are some compounding pharmacies on line that will ship out of state. There is one in Ohio that I use that is excellent. They ship the suppositories packed in ice packs and I haven't had any problems with that. But I live in the next state over so not an extreme distance away.
I finally found a local Osteophathic woman doctor that has been a true Godsend to me. She also prescribes a compounded progesterone cream based on my blood test. I have gone to MD gynecologists all my adult life will never go to one again. The extent of their knowledge for this condition seem to be to prescribe synthetic estrogen, and if you refuse that, recommend you get counseling and suggest an antidepressant medication. I am in no way a depressed person, I was stressed out from all the anxiety they helped cause me with their attitudes and lack of caring. Good luck and God Bless you all, I know how awful and stressful the symptoms of vaginal atrophy can be.
Patricia (Denver, Co) on 04/28/2014:
Sue (Cambridge, Oh, Guernsey) on 05/07/2013:
James (Denver, Co, USA) on 09/09/2012:
James (Denver, Co, Usa) on 07/15/2012:
So I found this study that said 250 or so women used DHEA suppositories intravaginally for 12 weeks and reported that vaginal atrophy symptoms were relieved. They used varying strengths, to see if that mattered. As it turned out, the 3.25 mg DHEA ovule or suppository seemed to have pretty good results. I found a pharmacist that reported some of their customers had success with 3.25mg DHEA vaginal suppositories (or ovules), inserting 1 suppository nightly for 12 weeks, then 2-3 times per week thereafter. Has anyone tried this?
Another study I came across, the participants utilized a vaginal suppository containing hyaluronic acid sodium salt 5 mg, vitamin E acetate 1 mg, and vitamin A palmitate 1 mg. Dosing was a suppository intravaginally every night for 14 nights, then tapering to every other night for 14 nights. Of 150 women, 126 women completed the study in full. The study assessed efficacy of the study medication in the areas of burning, itching, inflammation and irritation. Results showed that any symptom that was reported as severe initially was resolved to either mild or absent at the end of four weeks. Anyone ever heard of this?
My wife's in a very demanding job, and doesn't have time to research this, so I'll be checking back to hear from you as to what works for you, while I continue to research further and report anything new I find.
Sue (Cambridge, Oh) on 06/05/2012:
Sue (Cambridge, Oh, Guernsey) on 05/31/2012:
But I have found something. DHEA inserted vaginally. I am well lubricated and it does not hurt to have sex. I bought some DHEA, 5 mg. Then I break the tablet into four pieces with a pill splitter. So I am getting a little over 1mg which is enough vaginally. Also, it does to systemic because my skin is significantly oilier. I have been on this for about six weeks with no spotting (estrogen makes my fibroids grow).
Some people say DHEA converts to estrogen and testosterone. I do not know yet if it is converting to estrogen, but my body will tell me. So with that in mind, it probably would not be good for someone with cancer or who is prone to cancer. I would say to ask your doctor, but doctors generally don't know any more about this sort of thing than a fly knows about computer programming.