Heidi (Ogden, UT USA) on 03/08/2009
WARNING! If you have bipolar disorder, avoid St. John's Wort. My husband has BPD, and used st john's wort for a full year before having any side effects, and when they came, they were a DOOZY!He said he felt like his brain was sitting on a frying pan and sizzling, and if he'd had a gun, he would have shot himself in the head, not because he was suicidal, but simply to bring an end to the sizzling sensation.
It took a year for the herb to saturate into his system enough to bring this on, but it was a VERY unhappy side effect for him. It lasted an entire afternoon, three or four hours of brain sizzle. Not something he ever wants to repeat.
Sandra (Inchigeelagh, Cork, Ireland) on 03/07/2009
I just wanted to mention a possible side effect of St John's Wort. I started taking a German preparation (they have done some of the most extensive studies on the herb, and regularly prescribe it for depression). 900 mg once a day. I happened to go to my doctor a week after starting. My usually normal blood pressure had skyrocketed to 180/100. I had been feeling a bit jumpy and recognised the feeling as I had previously experienced a massive increase in my blood pressure from taking licorice. I immediately stopped taking St. John's Wort and within two days felt a lot better in terms of the jumpy-ness. I will not have my blood pressure taken for another few weeks, and unless you hear from me again you can be sure it's back to normal. I've read studies that say the herb does not affect blood pressure, but I can't help thinking that the people in the study were not super sensitive like myself.
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