5-HTP for Depression

5 star (8) 
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1 star (1) 
  10%
(1) 
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Misty (Indiana, US) on 07/18/2014:
0 out of 5 stars

5-HTP gives me terrible nightmares. It seems as if every night I am waking up screaming or crying, which has never happened to me even as a child. Every night for 2 weeks, I have dreamt that horrible things happened to family members, friends, and me. I also get these weird hallucinations when I am about to drift off to sleep where suddenly I see a giant spider or something on my pillow, then I'll scream and wake up. It is all but impossible to get up in the morning, even when I am done sleeping.

I started out taking 100mg before bed, then gave it a week and tried 100 in morning and 100 before bed, gave it another week and tried 100 in morning and 200 before bed, then tried 100 in morning, 100 in afternoon, 200 before bed, which I've been doing for the past 2 weeks. It does not seem to be helping my depression at all; in fact, it seems as if it has gotten worse.

REPLY   1      

Neukoln (Edinburgh, Scotland, Uk) on 02/08/2013:
5 out of 5 stars

I too had very good results with 5HTP. I was initially taking too much and got the anxiety that people mention. But I cut back the dose and it is so much better. I think people need to experiment with the times of the day that is best for them, and the dosage. I open the 100mg capsule and take 50mg in a tiny bit of water 30mins before breakfast - it helps get rid of the morning catatonia. I take 100mg in a tiny bit of water 30mins before dinner - it helps get rid of the comfort eating in the evening. And I take 50mg in a tiny bit of water at bedtime. I think you need to take it on an empty stomach. It seems to work better that way. But 5HTP definitely works for me - it was matter of finding the right dose and time of day to take it.
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Steve (Las Vegas, Nv Nevada) on 02/07/2013:
5 out of 5 stars

When I was going through extreme depression due to adrenal exhaustion I found taking 5HTP pulled me right out of the depression. I knew my serotonin was low and the 5HTP brought me back to normal levels. I started with a dosage of 50mg and gradually increased until I felt I could smile again. I beleive 5HTP is as close as you can get to the actual serotonin produced by your body.
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Brian (Boulder, Co) on 03/02/2012:
1 out of 5 stars

Warning

My caution is quite different: there is a VERY good chance your doctor will advise against 5-HTP (or any natural remedy). For many, that avenue then becomes a dead end.

I use 5-HTP now after being prescribed pharmaceuticals, and it is at least as effective. The dark secret about meds is that for many of us they don't do much in the first place, and eventually they destroy your liver (which happened to my sister, with many serious health consequences).

My advice for wearning yourself off your meds (which is what I did) is to do it VERY slowly, and introduce 5-HTP as slowly. At least 3 months, until the dosages you are taking are just tiny crumbs. This will keep your side effects down to a bare minimum. Good luck!

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REPLY   2      

Joylie (Solana Beach, Ca) on 08/15/2011:
5 out of 5 stars

I love 5-HTP. It has helped me while I've gone through some pretty tough times. I just take 50 mg. Every night. But even at that lowest dose, it has made a big difference for me. :-)

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REPLY   1      

Linda (Atlanta, Ga) on 07/01/2011:
5 out of 5 stars

5HTP helps me very well when I have the Blues. I take only 50mg in the morning. It works very subtle. I notice when I do not take it. I also take PS (Phosphatidylserine). It helps me get up and do my work and it helps me with procrastination. I found with 5HTP that it works better in low dosages. When people take too much they experience anxiety.
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Denisse (Long Beach, CA, USA) on 05/07/2009:
5 out of 5 stars

5-HTP for depression. This little pill did wonders for me. I had been feeling depressed for around a month due to heavy family problems. When I finally put all my symptoms together (oversleeping, hopelessness, sadness, emotionally unstable) I instantly came to this site. Cold showers did not appeal to me at all; I live in sunny CA and still get cold. I ordered the pills and thankfully they came the next day. I take one or two (depending on how I am doing) 100mg pills a day. My mood has definitely improved and I am finally returning to my normal self. They also seem to have reduced my terrible headaches. I recommend 5-HTP to all!
REPLY   5      

Kellie (Vancouver BC, Canada) on 01/13/2008:
5 out of 5 stars

Hi I found 5 htp a couple years ago on the internet , looking for some thing to help my saddness and depression, so i heard about 5 htp , well i was desprite and i took 2 100 every day , it helped me so so much , i go off it some times because the side effects for me are, it makes me get my period more ofton , mind you i think that is when i was taking 300 mg . and also it has caused me to get itchy palms of my hand ,and the back of my head . but now that iv gone down on them and taken a break for a few months , im good . but i have to go on them because it helps me so much for depression . i have just discovered the 5 htp with 200 mg L- Ter , wow as far as im concerned its a bloody mirical . it changes my hole mood . makes me very happy .but for sure one other side effect im not as hungry when im on it . and i dream more vividly . but as fare as im concerned its a wonder drug , sorry for the spelling.lets just hope the drug companys don't take them away.
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Karin (Arlington) on 08/29/2005:
5 out of 5 stars

5HTP has been one great discovery for me and several of my friends. We used to all take Valerian root which worked great but smelled awful. St. Johns wort wasn't bad either, but there was concerns about taking before surgeries. We've been taking 5HTP for over a year now and there is always this significant sense of calm.
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Charlotte (Richboro, PA) on 03/01/2004:
5 out of 5 stars

My 6 year old grandson was diagnosed with "Select Mutism" 2 years ago and rather than put him on "Prozac", my daughter did some research and learned about 5HTP and chose to try it first. He started on 50mg every night. His psychologist saw the same results with the 5HTP as children on prescribed drugs. It's been a miracle for him. I have since then also taken it since our family seems to have anxiety problems and ADD runs in the family and it has helped very much with these problems. I usually take 100mg to 200mg daily depending on my stress levels at the time. We are so grateful our little grandson did not have to take Prozac or a similar drug. I would highly recommend it as a first choice to try at least.
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