Acanthosis Nigricans Remedies
Modified on Mar 12, 2024
Acanthosis Nigricans is a benign dermatologic condition in which velvety grey-brown or black plaques develop on the skin. It generally occurs in areas of skin folding such as the back of the neck, armpits, or groin.
It is associated with a variety of endocrine disorders such as Addison's Disease, Cushing's Disease, and hypothyroidism. Rarely, acanthosis nigricans occurs in the setting of cancer or in association with other uncommon genetic syndromes. The most common cause, however, is insulin-resistant states such as diabetes mellitus. In addition, there is an association with obesity, itself a contributing factor to insulin resistance.
The exact cause of acanthosis nigricans is poorly understood. It is thought that high levels of insulin (as seen in diabetic patients) stimulate growth receptors in certain skin cells, leading to the characteristic hyperpigmented plaques. Acanthosis nigricans treatment is generally affected by addressing the underlying cause, most commonly obesity or elevated blood sugar. The simplest and most effective means of combating these problems are diet and exercise.
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