Replied by Ron (Michigan) on 09/09/2025
I don't know of a natural cure, but some information is helpful to know.
Newer research is showing that in resistant hypertension sometimes requiring more than one or two Blood Pressure medications, there may be 20-30% who have primary or secondary aldosteronism.
The kidneys and adrenal glands regulate blood pressure (aside from having atherosclerosis, clogged arteries and veins, etc.) in a feedback loop involving renin, aldosterone, angiotensin I and II and it's call the Renin-Angiotensin-Aldosterone System (RAAS).
The diagnosis is not made in one step. A first step is to test for the Renin Activity Level and then the Aldosterone levels. There are different ratios between the two, the Renin Activity and the Aldosterone levels. One can have low renin or high renin activity and still have the high blood pressure.
See the Primary Aldosteronism Foundation for excellent explanations:
https://primaryaldosteronism.org/pa-is-an-endocrine-disease/
Higher aldosterone levels may be caused by very small, benign, non-cancerous nodules on the adrenal gland atop the kidneys. If only one is found, they do a laparoscopic surgery to remove it, and treatment is more effective if there's only one small nodule on the adrenal gland.
Medications may also be given to handle the higher than normal aldosterone production, but results are mixed depending on the individual case.
Because a medication may block the receptors for the aldosterone being naturally produced, the body counteracts that medication effect by producing even more aldosterone, so whether a treatment is a prescription medication or a natural, non prescription medication were to be found, the body would counteract that action by the treating medication and dosage would have to be raised, which is done.
So, it seems that a natural or prescription medication treatment is not without its problems and also side effects of whatever is used, and if a small, laparoscopic surgery can solve the issue, which it can in many cases, then the docs prefer the surgical route which is effective and has a statistically very low risk factor.
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