Most Recent Posts

Vitamin B12 Side Effects

Debbie (Aurora, Illinois ) on 07/15/2022
5 out of 5 stars

My B12 levels get very low, but because of cobalt sensitivity, I break out in an extremely itchy rash when I take it. It happens when I get injections and when I take over the counter supplements. I have an oral spray, a B complex, B12 alone, even multivitamin, they all cause me to break out in a rash? Anyone else have and even solve this dilemma? I sure could use some advice.

Vitamin B-12 for Pain

Hopejones (Sacramento, California) on 04/27/2017
5 out of 5 stars

I use B-12 for pain all over my body. The fastest pain release for me. I put it right on the area of pain. Pain gone in minutes after applying.
REPLY   5      

Re: Pernicious Anemia

C-bri (Cazenovia, New York) on 01/05/2014
5 out of 5 stars

After nuclear testing at the hospital because of pernicious anemia (probably 15 years ago), it was determined that I can't absorb B-12 in my intestine (auto-immune problem). Since that time I have been taking nascobal a prescription nasal spray one a week. Recently, I found it easier to go to my doctors office once a month for a shot of B-12. You do not want to fool around with pernicious anemia.
REPLY   2      

Size of a B12 Molecule?

Susan (San Francisco, Ca) on 05/15/2013

I read somewhere that the Vitamin B12 molecule is too large to penetrate the skin. Does anyone know of a website that lists molecule sizes (I haven't been able to find one) of various things (obviously including Vit B12) and what will or will not be absorbed by the skin? I've been using DMSO with B12 in it and would like to know if I'm wasting my time by using it this way. Thanks so very much!
REPLY   2      

Help Requested For Wife With B12 Deficiency and Other Ailments

Mark (Newton Abbot, Devon Uk) on 05/14/2013

Hello, am writing with regards my wife Jo she is 46 years old, as a vegetarian of 30 years she was diagnosed with a vitamin B12 deficiency in Feb 2012 so far high intake of Jarrow sublingual 5000 mcg methylcobalamin b12 (2 x daily) has failed to improve her condition, her original blood reading last year showed a low 162, with the supplements her blood level increased to around 2000 after a few months, unfortunately this has not resulted in any positive improvements occurring in over 12 months Her Gp is not overly helpful in anyway. This is a quick list of her current obvious symptoms, there are many more though.

Brain fog permanently
Burning/painful hands feet and face.
Shooting pains in neck and back
Constant back pain
Constant joint pains
Extreme fatigue throughout whole body (struggles to stay awake throughout the day)
Lack of power in arms and legs (left side much weaker than right)
Heavy numb feeling throughout whole body, especially arms and legs
Unsteady on feet sometimes
Eye sight deterioration

Giving blood is almost impossible (nothing comes out no matter how long the nurse tries)
Severe tinnitus (since childhood but now far worse)
Odd perception sensation through sight (things appear more distant than they are)
Small white patches on skin around neck and head area
Thought process difficult

Cannot eat any meat without severe stomach upset / bloating (tried to eat meat again after 30 years without it)
Struggle to get started in the morning (no energy even after sleeping well each night)

Jo has always tried to stay extremely healthy she still manages to weight train, exercise and go to work as normal, she only ever eats mostly whole organic produce, is a non-smoker and a non-drinker she never uses any chemical based cosmetics or household cleaners only natural based variants, Jo is still functional but things are really starting to get difficult lately.

It would appear to me that the B12 in her blood is for some reason unable to do its job at a cellular level, I have been reading much on line especially on your site which I have become very fond of over the past year or so, We now believe she may have other factors and not just B12 causing her issues, I frequently read about the importance of glutathione and other essential elements such as zinc and amino acids, it appears her normal b12 pathways are being interfered with at some level, I was wondering if you are able to offer any advice or to suggest any tests that should determine where her problems lie and how best to treat her condition, I have of course read through your site and corresponded on a few topics but still to date her cause and remedy still eludes us, I was simply wondering how you as natural health advocates would approach this issue if in our situation.

I would very much appreciate your response in this matter.

Yours sincerely,

REPLY   5      

Why Are B-12 Levels Low?

Diane (Framingham, Ma) on 01/26/2013

My vitamin B-12 is twice what it's suposed to be. Is there a reason for that and what should or can I do for it?

Sublingual B-12 Not Being Absorbed by Cells

Josie (Nashville, Tn) on 01/02/2013

Does anybody know WHY the following might occur? Blood test taken several years ago revealed low red blood cell count and wide blood cell width. I learned this means B12 deficiency. Thinking I might have pernicious anemia, made sure to take SUBLINGUAL B12. Took anywhere from 1000 to 5000 mcg a day sublingually, sometimes with folic acid.

A year and a half later, after having continually taken the sublingual B12, had another blood test. Although serum blood showed a very high level of B12, the cells don't appear to be getting it (still had low red blood cell count and wide red blood cell width). For well over two years, now, I have suffered from ataxia (very uncoordinated), muscle weakness, and exercise intolerance. Extremely weak and fatigued - very little to no stamina. Also, have suffered balance issues (to some degree improves with the sublingual B12). Have ruled out all gastrointestinal issues (no, it's not hepatitis of any kind, nor liver disease, although I have elevated liver enzymes). Also, ruled out rheumatological issues, muscle diseases, and metabolic disorders. Does anybody have any idea why such a high B12 level in the bloodstream, but the CELLS are NOT getting it? Thanks for your help.


High Vitamin B-12 Levels

Debbie (Billings, Mt) on 12/20/2012

What does one do for high B-12 levels. Mine are 1283 (normal is 180-914). I've heard that high B-12 levels are a sign of serious liver disease and yet I have no obvious symptoms.
REPLY   1      

B12 Corrected Health

Rosemary (White Rock, B.c., Canada) on 03/02/2012
5 out of 5 stars

I am a 55 y.o. woman and have had balance and vertigo issues for 11 years now. The vertigo stopped on its own at least 4 years ago (I believe it was menopause related) but the almost drunken walk problem (very embarrassing) only went away when I started taking B12 methylcobalamin subliminally twice a day. I have to add as well I take 1/8th tsp Borax in 1 liter of water most days as well for foot bone issues and that may be helping as well. I was greatly improved within a week from the B12. The numbness in my hands has stopped, the pins and needles feeling in my feet has disappeared and my leg strength in my knees has vastly improved. I also have a clearer head and more energy. I should say I am slim and workout at a gym on a regular basis. A simple blood test showed the lack of B12 no doubt caused by very little meat comsumption. My research showed B12 is lacking in older peoples diets.


causes of vitamin B12 Deficiency

Eating a diet that contains no meat or animal products

poor absorption due to cetain disease conditions or surgery

Surgery to the stomach or intestine

Oral contraceptives (the "pill")


Symptoms of Vitamin B12 Deficiency
Similar symptoms to that of Folic Acid deficiency (see above) including:

Nerve damage

numbness in hands and feet

Tingling (pins and needles) in hands and feet

Weakness in legs

Pale skin

Poor memory

Poor muscle coordination

REPLY   1      

Benefits of B-12

Connie (Slc, Ut) on 05/04/2011

Hey Y'all; Here I come out the bushes again, a naked goose with a tart tongue... I'll just remove this hat. My father announced to me, ( probably upon my provocation), that marijuana made him vomit. He recounted that one evening, he attended a party, drank 2 vodka martinis, had 2 draws off a marijuana cigarette, and then vomited. " And all I ate that day was a half a bologna sandwich and a valium! " It still makes me smile. Cannabis is an antiemetic. I admit that it can be very difficult to pinpoint the offending substance when I'm experiencing negative symptoms.

Nowadays, we're taught to fear or dismiss the very substance that could help us. Sometimes we don't get good results because the substance is combined with chemicals that interefere with its bioavailability. Sometimes, it must be taken orally, sublingually, and or parentally. (injection) This is true for B-12. I've been visiting many websites to try and understand why some people that seem to need this substance, do not have positive results with it. Of course, they may not need it. Some practioners believe that folks with high histamine (low- methylators), may have a negative reaction. ( I haven't measured my histamine, but I do flush hard and long after I take small amounts of niacin). Some researchers and B-12 deficient folks question the accuracy of testing. It is thought that serum B-12 is not a good indicator of the cerebrospinal content of B-12, for instance. So many of us are left with the choice to test ourselves and observe our own results. We try to distinguish what are and what are not the effects of this substance. This process is extremely difficult because it is truly impossible to completely isolate a substance and it is even less possible to suspend bias. But we try.

In my search of many sites that list the benefits of B-12 and my own results, I've found this list to be huge. I recommend that you visit Pernicious Anemia.org, and b12d.org for more information about it. Meanwhile, I'll include a list of more benefits that may interest folks here. B-12 may help these ailments : Canker sores, Shingles and Herpes outbreaks, Allergies, Constipation and Diarrhea ( when cause is vagus nerve disturbance), Depression and Anxiety, Greying Hair, Hairloss, General skin conditions including Hypo and Hyperpigmentation, Ridges in nails, Vertigo, Labored Breathing, Shocking nerve pain, Vibration of Nerve channels, (described as "cell phone vibration" here). This list is a fraction of what I have encountered. Of course, We know that there is no single substance that works for all, but its worth a try, possibly.

REPLY   1      

B12 for Multiple Ailments

Connie (Slc, Ut) on 04/07/2011

B-12 For many ailments

Hi y'all; I've wanted to post suggestions to people with these particular symptoms, but I was having so many recurrences- I began to have doubts that I could help. A recent blood test brought me to realize that the recurrence of these negative symptoms were because I was not taking B-12 with enough frequency. My long time condition of macrocytosis (big blood cells) had returned. It's probably pernicious anemia, a B-12 deficiency of an autoimmune cause, because I consistently need high amounts of it to stop and reverse the nerve damage that keeps reappearing when I try to reduce it. Many people may have a B-12 deficiency for reasons of : low consumption of foods with it, low stomach acid, intestinal absorption problems, and medication interactions.

The symptoms that B-12 supplementation has relieved for me are so many, that I hardly believe them, but it doesn't matter, I don't even have to believe it; the relief happens anyway. So here goes : Numbness, tingling, pain, of hands, feet, lips, tongue, flank, and gums. (3 years ago, my left hand was becoming claw-like and I nearly lost the use of it. I'm left handed. ) My right foot would shuffle along beside me. My left big toe would present with distractive pain. My vision was blurred and doubled. My hearing was decreased, and there was intermittent tinnitus. I was very irritable and paranoid with very poor memory. There was worsened insomnia and poor physical coordination. I was unable to recover from a PTSD episode, and memories of other traumas began to recur when I was B-12 deficient. I have a long history of IBS, constipation, diarrhea, and flatulence that was not completely relieved by probiotics, magnesium, or potassium supplementation. I have a long history of anxiety, depression, and OCD, (trichotillomania, hair pulling). B-12 has brought immeasurable relief from these conditions for me. Some of these conditions may take a year to relieve. Please tell others of this.

With restarting B-12, I have also noticed that it has helped me with an hypersensitivity to acids. I've been reducing acids in general, to my great benefit, but I was having to become ridiculous about it. Apparently, B-12 is rebuilding the sheaths of my nerves so that I'm less vulnerable to acids. It also is active in metabolizing many acids. I have found it to have no negative side effects for me, but it does have an antagonistic relationship with potassium. If someone with low potassium begins supplementing B-12 in large doses, there could be trouble. I suggest caution. There are many symptoms that low B-12 and low potassium share, such as anxiety, fatigue, insomnia, irritability, shortness of breath, heart palpitations and more. Taking potassium with B-12 has sped my recovery from nerve damage. For now, I'm going to take 1000 to 5000 mcg. Of sublingual methyl- B-12 daily. I also take B-complex and a little extra folate. (400 to 800 mcg. Folate is powerful. Caution). Meantime, I'll continue to treat my liver well, and negotiate this autoimmune business. But I am grateful to this buxom red jewel of a molecule!

REPLY   1      

B12 Feedback

Janie (Mattoon, Illinois) on 01/05/2009
5 out of 5 stars

First of all I absolutely love this website! It is so helpful and... eye-openingly refreshing!

I am a vegetarian and know the importance of getting protein especially. Little did I know until later that I wasn't getting enough protein when I thought all along I had! Last year I went through a sleugh of tests to try and figure out why I was having this God-awful stabbing,jabbing pain directly below my right rib cage which to me, felt like a heart attack. It seemed to flair up an hour or two after a meal. I also suffer from Gerd so I would somehow associate it with that. But, I would have this uncomfortable pain consistantly every day -And it was more apparent at night or in the wee hours of the morn. My doc thought it might be gallbladder so I underwent tests for that. They came back Negative. During the many visits and not to mention the dollars spent trying to get to the bottom of what was causing that pain - I decided to get up on the internet to try and find the answer myself. Realizing that I am a vegetarian and have been for many years, I checked out everything food related and that I needed in the way of nutrtion, that was beneficial to my living this vegan lifestyle. During the research I found that a lack of B12 could be the cause for this sharp, unexplained pain that I was having - and I had been having it for more than a year or so - Anyways. to make this long story short, I went back to the doc. Told her what I found that might be causing this pain - She ordered up a blood test and found out that I was deficient in B12! She didn't want to give me the shots so I was put on B12 supplements that she recommended from the health food store ( Must contain methylcollomin - check my spelling on that word though ok?) - Anyways,after taking the 1,000 mcg's of B12 - 2 a day at first - now down to one,the pain was gone almost immediately (with-in a week I'd say) and remains to be gone to this day!!!! Yeah.... The brand I take is B12 Infusion by Enzymatic, for those of you who might be interested. Thanks for letting me share my story.
REPLY   5      

Terry (Vancouver, Washington) on 04/16/2008
5 out of 5 stars

I went to your site on Hives. I had been suffering with a red rash on my legs, shoulders, arms and middle of lower back for about 2 months and I itched untile I bleed. I had been using a Hydrocortisone cream 1% with Aloe with NO results. I had discovered from your site where people had been getting good relief with ACV and A 90% cure rate with Vitamin B-12 at one milligram a day. I started taking the B-12 and applying the ACV topicallly at least 3 times a day ( just pour on a cotton ball and apply ). I also started taking 2 T. ACV in an 8 oz. glass of water with 1/4 t of Baking Soda. I figured if its good for the outside of the body it couldn't hurt me on the inside. I am happy to say it worked my rash and bumps are almost gone and there is no longer any rash that itches or bleeds., Thank you ALL for your contributions to this site. I was at wits end. Terry
REPLY   1      

Christine (Virginia Beach, USA) on 04/04/2008
5 out of 5 stars

Acid reflux is often caused by a Vitamin B12 deficiency. Since you need B12 to make enough intrisic factor and enzymes to absorb it, perhaps just taking ACV will help you absorb Vitamin B12 better.

Nevertheless, I have found that as long as I take 4 B12 dots (500 mcg) under the tongue once a day, I am fine. When I don't, the reflux comes right back.

REPLY   2      

Justin (Port St. Lucie) on 08/22/2006
5 out of 5 stars

I was under constant attack from anxiety, and depression was setting in because of it. I saw a therapist who taught me about positive thinking and ways to get myself out of a panic attack. It kinda worked but was a constant effort to always be managing my moods and still fighting random panic attacks. I started self medicating with a popular narcotic made to ease anxiety. We all know it as a small white rectangular pill. I became dependant and my tolerance built up way to high. I lost my job, and almost my wife and kid because of that stupid pill! I checked myself into a rehab...mainly to get it out of my system while in a secure, stable environment. My mind was definetly set on getting that pill out of my life so it was easy to kick. When I got out I was so scared of my anxiety coming back...and it did! I then remembered someone telling me about B-12 and Folic Acid as a natural cure for anxiety. I went to the store found the vitamins and saw it was like $6 for a 3 months supply and said "what the heck, I'll try it".....2 years later only one ten minute panic attack! The one I did have was after a night of drinking and did not take my vitamins...so def. my own fault. I take 500mcgs of B-12 and 400 mcgs of Folic Acid twice a day (i'm a big guy) I rarely, very rarely even think of my anxiety.

I have also, overtime, added a supplement called 5-htp and always carry around Altoids. I take the 5-htp when it just feels like things aren't going my way, and within an hour I am as giddy as a 3yr old watching blues clues! The Altoids help me out just whenever, they give me my own personal break from everything. The freshness it gives just puts everything back on a balanced level. The extreme peppermint taste relaxes me. I pop one in before any stressfull meeting, event, issue and i'ts like my own personal shield from stress!

As a side note since taking these new vitamins I have only been sick with a cold for one day out of 2 years! I have not gotten a single sore throat, flu, ear ache...Everyone in my family can be sick and I get nothing! I feel invincible! Smiling more.

REPLY   7      

Anonymous (USA) on 03/01/2004
5 out of 5 stars

re: Bursitis: Dr. Jonathon V. Wright says that taking 1000 mcg. shot of B12 every day until the pain goes away and then a couple more to make sure you have enough, always works.
REPLY   2      

B12 Feedback

Kim (Sussex, England) on 08/24/2008
5 out of 5 stars

I was reading some research about B12 having a beneficial effect on patients with Alzheimers and people who had forms of depression. As a 76 year old, I am concerned to keep my mental health as active as I can. For the last few weeks in addition to my vitamins and minerals, I also take three or four 5000 mcg Vitamin B-12 tablets a day and let them dissolve in my mouth. I also started taking Ginko Biloba and Siberian Ginseng. My energy level has improved immensely and I find myself in a jolly good mood. I've had a bad memory my entire life, so I would be very surprised to see improvement in that area.