Replied by Art from California on 06/09/2025

Hi Vaibhav,

I talked to Avery and he said he is scheduled for another CT scan in September for his aortic aneurysm. If he gives me those results then, I will post them.

Art

Replied by Vaibhav from California on 06/15/2025

Hi Art

I am 40 yr old and my aneurysm is around 5.45, I want to try some of the remedies you informed if it can make my aneurysm stable or decrease in size. What you will recommend me?

Replied by Art from California on 06/16/2025

Hi Vaibhav, I am not a doctor so I can not tell you what to do for your aortic aneurysm. I reported Avery's significant results with him using the specific supplements that he described here : Https://www.earthclinic.com/cures/enlarged-aorta-aortic-aneurysm.html It would be a good idea, if you have high blood pressure, to get it into the normal range. If you smoke it would be very good to stop smoking as both smoking and high blood pressure are significant contributing factors to aortic aneurysm. Art

Replied by AManda from Florida on 07/24/2025

HI Art,

My husband has been diagnosed with ascending AA at 4.2. They want to watch him for a year on blood pressure meds, beta blockers and blood thinners. He also has current AFIB. Any know interactions with AFIB as well? I have ordered 5 of the supplements to have him start. Also, is your friend still on them or was there a timeframe of the treatment? I see oral melatonin says 10MG for 6 months only at a time.

Replied by Art from California on 07/24/2025

Hi AManda,

Since your husband also has AFib, his doctor will have to approve any supplements he takes to be sure that they will be compatible with all of his meds.

You might also be interested in a recent post I made regarding AFib here :

https://www.earthclinic.com/cures/atrial-fibrillation3.html#mgmo

The above will also require his doctor's approval even though it is a topical application.

Avery is going to get retested in August or September if I remember correctly and hopefully I can share those results here.

Art

Replied by Jay from Boston on 08/17/2025

Thanks, Art for the superb research you do. How can I do this caliber of research? Once I select an ailment to solve using the internet, what steps do I take to locate good studies and information? Thanks!

Replied by Artr from California on 08/17/2025

Hi Jay,

That is a question I have not given much thought to before now. I've been doing this for so many years, it is like second nature to me. I will have to give that some thought, but I can say that a lot of information or clues are in my mind after many years of reading studies and researching. I have that basic knowledge already in my head and use that to try and help me focus on where to look for answers and solutions. That probably doesn't help you much, but that is basically how I research. I seem to retain certain things that I read and that helps me to know where and how to look for what I want to know.

Art

Replied by Jay from (Boston) on 10/16/2025

I see, Art, thanks. Have you used any particular AI platform(s) to obtain non-pharmaceutical/alternative solutions to health issues?

Any thoughts on how to use AI for health sleuthing?

Thanks

Replied by Art from California on 10/16/2025

Hi Jay,

AI seems to have improved over the past two years, but it is not bullet proof by any stretch of the imagination.

Currently, AI generated research still requires that you research (fact check) everything that it comes up with because they are not always accurate, so I still have to do my own research. What I do find AI useful for is organizing my research into a much more understandable and organized format that is well beyond my capabilities.

AI is a highly competitive and rapidly growing industry with so many players now, it is almost ridiculous. The highly competitive atmosphere, in my opinion, is making programmers do things that may not be the best for research in general and at this point the individual AI platforms seem to only be as good as their programmer makes it.

There is a tremendous amount of variability from one AI to another. As an example of two big ones, in my opinion, Google AI and Chat GPT, Google seems to be over cautious in the information it gives and seems to lean away from stretching the known science to its limits, while Chat GPT seems more willing push the envelope a bit. Both methods have their drawbacks and the highly competitive AI market throws another wrench in the works.

Bottomline is that I am still doing my own research and using AI for its organizational skills, rather than research skills.

Art

Replied by Amanda from Florida on 10/17/2025

Hi art! Any update on your friends scans?

Replied by Art from California on 10/18/2025

Hi Amanda,

Yes, Avery went for another CT scan very recently and his current number is 4.0. Originally it was 4.5 and then it went down to 3.8 and is now 4.0, which is fairly close to what would be expected at his age.

When I talked to Avery about it, he said he was still taking the zinc, selenium and quercetin, but he had stopped using the melatonin lotion(ML) twice a day and was only using it irregularly. He said he will go back to applying it twice a day again.

Apparently the ML is one of the more potent components of this regimen.

The following animal research abstract tends to confirm that idea :

https://pubmed.ncbi.nlm.nih.gov/32329099/

Here is a very relevant quote from the abstract :

' Melatonin functions as an endogenous protective molecule in multiple vascular diseases, whereas its effects on thoracic aortic aneurysm and dissection (TAAD) and underlying mechanisms have not been reported. In this study, TAAD mouse model was successfully induced by β-aminopropionitrile fumarate (BAPN). We found that melatonin treatment remarkably prevented the deterioration of TAAD, evidenced by decreased incidence, ameliorated aneurysmal dilation and vascular stiffness, improved aortic morphology, and inhibited elastin degradation, macrophage infiltration, and matrix metalloproteinase expression. Moreover, melatonin blunted oxidative stress damage and vascular smooth muscle cell (VSMC) loss. Notably, BAPN induced a decrease in SIRT1 expression and activity of mouse aorta, whereas melatonin treatment reversed it. Further mechanistic study demonstrated that blocking SIRT1 signaling partially inhibited these beneficial effects of melatonin on TAAD. Additionally, the melatonin receptor was involved in this phenomenon. Our study is the first to report that melatonin exerts therapeutic effects against TAAD by reducing oxidative stress and VSMC loss via activation of SIRT1 signaling in a receptor-dependent manner, thus suggesting a novel therapeutic strategy for TAAD. '

The above mouse study clearly suggests that melatonin is quite useful for thoracic aortic aneurysm in a mouse model and Avery's results that the benefit may also apply to humans, but a human study is required to confirm this. Such a study is definitely warranted because cardiologist seem to agree that they can not shrink an aortic aneurysm without surgery and of course there is significant risk involved with that surgery.

So based solely on Avery's experience, he seems to have responded fairly well to this regimen and especially to the topical application of melatonin lotion over his aorta area on his front and back twice a day applied sparingly.

Art

Replied by Amanda from Florida on 10/19/2025

Can you use oral melatonin?

Replied by Amanda from Fl on 10/19/2025

And where do you get the cream?

Replied by Art from California on 10/19/2025

Hi Amanda,

I will answer both your questions in this reply.

Where do you get the cream?

You have to make it yourself as I have not found a commercial cream that is as strong yet and I describe how to make it in the following post :

https://www.earthclinic.com/supplements/melatonin-lotion.html

Can you use oral melatonin?

You can use oral melatonin also, but I don't think it will be strong enough or last long enough by itself. The melatonin lotion is needed to last long enough and reach high enough local tissue levels to be more effective than just oral melatonin.

Art

Replied by Amanda from Fl on 10/19/2025

Am concerned about the Gin. May be a stupid question but does it put alcohol in their system?
and does it matter the brand of gin?

Replied by Art from California on 10/19/2025

Hi Amanda,

If you were to apply straight gin to the skin it would have a drying effect and act as a moderate irritant. When diluted with the lotion on a two parts lotion to one part gin basis along with the dissolved melatonin, the botanicals that the gin is made from have potential to offer benefits of their own while the melatonin has proven skin protective effects and the lotion prevents the skin drying potential of the gin.

It might be worthwhile for you to read all of the replies to the original post to get a better idea of what people have experienced from using melatonin lotion and any side effects they may have experienced, and then decide if you think it is worth testing.

Art

Replied by Art from California on 10/19/2025

Hi Amanda,

To answer your questions, if the alcohol can enter the system it is a very small amount incapable of causing intoxication with most of the alcohol evaporating upon application of the lotion. The gin is used to dissolve the melatonin powder.

I just use the house brand gin that I get at Costco in a large bottle.

Art