Replied by Charity from faithville, Us on 08/02/2021

Hi Art,

Nice to see a list of helps for memory. My memory issues were two fold, split personality . In that your parts would pop up into the front and listen to something and then go into the backdrop with the information and the core person had no clue what went on. I don't have that anymore, Praise the Lord for showing me how to get whole. Now the other thing is digestion . The gut affects everything. I take a couple of things on your list plus magtein, coconut oil, water, salt, and a whole lot of supplements to catch up on old problems depleting me. You might like this article. I read death by calcium at the library a long time ago. Interesting that calcium needs silica, boron, all the minerals in balance, D, and K and some other amino acids to get it into bones and teeth and keep it out of soft tissue.

Should I Take Vitamin K with my Vitamin D Supplement? (myhdiet.com)

Replied by Art from California on 08/02/2021

Hi Charity,

It's good to connect with you!

Thank you for the info on supplements needed to direct and manage calcium properly. Interestingly, melatonin has recently been established as healthful for warding off osteoporosis and osteopenia so it should fit well with the ones you mentioned. In the mouse spine, it has shown the ability to reduce or reverse disc degeneration.

I will take a look at your link in a moment, thank you!

Art

Replied by Pacific Coast Lady from Crescent City, CA on 02/18/2023

Hello Art, I realized this is a fairly new post so I hope you will see my reply :) It's interesting that I would find this just when I am realizing I have the same issues that your friend has had.

I enjoyed reading your whole article, then researching the supplements you listed. I'm started with the D-3 as you suggested in your addition to your article (order of supplements). The rest I am not sure about yet, whether I should try them or not. Lecithin I think, it's been a couple or more years since I tried it, gave me some side effects.

I'm 70 and on the far NW corner of CA near the border of CA and Oregon. I have T2 Diabetes, under control with a ketogenic diet, no pills, and regular walking and weight-training. If anything has a side-effect, I seem to be susceptible but I am good with D-3 and was diagnosed as being deficient in 2018, but I didn't continue to use the 'script. It's better for me financially if I can have a script instead of buying out of pocket.

I'm sharing the info at my senior forum but few are taking notice. Neither Dementia nor Alzheimer's runs in my immediate family, or my grandparents but I don't like how dull my mind is in some areas. I also take only Magnesium 500mg 2 x per day right now, and an anxiety drug called clonazepam, 1mg per day.

In 2 years on Keto, I've lost 30 lbs with only walking 30 minutes 3 times per week. So my bod is in better shape, but the brain needs more of something. I'd love to be as successful as your lady friend :)

I can't thank you enough for sharing your information so thoroughly with us. I am a firm believer in trying alternatives to drugs, being my own guinea pig, rather than leaving everything up to the conventional Docs. I do believe there is a place for both, but I refuse not have my own medical records, and my own say in what I allow into my own body. I'm taking responsibility for my own health. Have been since I joined EC, Thank you again, Denise

Replied by Art from California on 02/19/2023

Denise/PCL, you're welcome!

You sound like you are doing a very good job in managing your own health!

The magnesium, exercise and keto are very useful for the diabetic aspect of your health.

Admittedly, my friend did not have a reaction to any of the supplements she tried, so she is probably pretty hardy in that sense. The lecithin was not part of her memory regimen, just strictly to lower her high cholesterol and it worked well toward that end making it possible for her to avoid the statin drug her doctor wanted to put her on.

If you decide to try the memory regimen, please update us on how you do and if you have a problem with any supplement during the testing steps, I can recommend one or two others that are also effective and have very good safety profiles. One of which also has anti anxiety effects. Allow at least 6 months to see noticeable results. Good luck!

Art

Replied by mmsg from somewhere, europe on 02/20/2023

PCL/Denise, read up about coconut oil for the brain.

Replied by Denise E from Crescent City, CA on 02/26/2023

Hello again Art! Yes, I will keep you all posted on my progress in trying the D-3, and I'm going to get the Lecithin as well since I have very high cholesterol, 358, and my doc tried for 2 years to get me to take statins but I won't because of the studies and other info I've read online. Even so I am nervous in it being so high, I hear that it's most important that the Trigs divided by the HDL number is most important in lipid panels. I'm not saying it's true, I'm just saying I am willing to follow, basically, Dr. Benjamin Bikman (and others) on this controversial subject. Especially since I've had success with my alternative methods for T2. I will also keep a notepad for any side-effects with any new supps I introduce in, this time around.

Replied by Denise E from Crescent City, CA on 02/28/2023

Hi Mssg, I have coconut oil every day. Although it's a small bit that I put into a cube tray that I pour my fat-bombs into for my ketogenic diet. For 12 FBs I use a 1/4 cup of Coconut Oil so I'm just getting 1 tsp a day as I have just one after my last meal of the day.

I will read up on it like you suggest though. I could add some other ways during a day as the coconut oil assures that I get enough good fats in my diet. Thanks so much for your for the info, Denise

Replied by Art from California on 02/28/2023

Denise, Sorry for the delayed response, I just saw this. The effective dose she used was two level measuring tablespoons of lecithin granules a day. She put it in 3 or 4 ounces of water without stirring and drank it straight down. Art

Replied by Denise E from Crescent City, CA on 03/01/2023

Ok Art, I've done my ALA, Lutein for 3 days now (but not my 2nd dose of ALA yet) and have had no weird issues. My Citicoline arrives today and D-3. When I've been into all of what I'm trying I will make another reply. I was so lucky on the prices, and also got the little gel capsules, or regular capsules so easy to swallow. Thanks again Art, I'm in your posts now to see if you have anything on PND or allergies, Denise

Replied by Art from California on 03/02/2023

Denise,

The 5 memory supplements are :

Vitamin D + Vinpocetine

Lithium Orotate

Citicoline

Melatonin

So it looks like you have the vitamin D and Citicoline so far.

Regarding PND, are you referring to Paroxysmal Nocturnal Dyspnea (PND) ?

If that is correct, I can save you some time as I haven't written anything about PND. The nocturnal breathlessness is generally caused by heart or lung problems or both and which ever of those might be the contributing factor in you is what I would try and go after. On that note, the melatonin in the memory regimen would be beneficial for both issues. There are others that would be helpful for the heart and lungs, but that is already on your list so it will be worthwhile to see how you respond to it.

Good luck and I look forward to your updates!

Art

Replied by Denise E from Crescent City, CA on 03/03/2023

I'm sorry I didn't specify PND, but it's Post Nasal Drip I struggle with, it's year-round, have air purifier, salt lamps in my smaller 1 bedroom apt. so I have 3 or those and keep things dusted and floors vacuumed.

I don't know of anything supplement-wise or herbal that might help me get rid of it, been going on at least 6 years. It help to irrigate my sinuses with Pink Himalayan salt, and my change of diet for last 2 years has helped so it isn't so think but I still have trouble in a.m.'s with voice issues, I constantly have to swallow as I cannot blow it out, or cough it up. It's never in my lungs and am positive it isn't coming up from my stomach like LPR. I also drink electrolyte (home-made for my water). It is clear mucus by the way, no infection detected. I'm just over-producing it somehow, can't figure it out. I do 1/2 cup of yogurt a day, and 1 ounce of cheese. I quit all that and it didn't make a difference so I don't think I have a dairy issue.

Feedback welcome, and I totally understand when you can't get right back to me, this is a huge site and you are helping so many of us. I do a lot of research most days, especially if I'm having a tantrum over just one of my issues, of which there are many things and mostly I learn to live with them until I think I can find answers the doctors never seem to find except a 'script and I won't do anymore unless I'm unconscious and can't tell them no, laughing out loud here. Denise

I think it is somehow also related to my tinnitus.

Replied by Art from California on 03/03/2023

Denise,

I see, post nasal drip (PND). If you haven't already tried it, you might consider Xlear Nasal Spray (XNS) at the maximum label dose. It has grapefruit seed extract (GSE) and xylitol in it and both have shown the ability to breakdown biofilms which can form to protect pathogens. GSE is a potent antimicrobial. I am currently working with a friend with a similar issue and she is starting off with XNS at the maximum label dose and said she will try and draw it in deeply with each spray to spread it as much as possible in her sinuses. She has had a constant sinus condition dating back to the 1970's so it may take a significant effort to try and ameliorate her sinus issue. She is going to go through a full bottle and let me know how she is doing.

So if you give it a try at max dose, keep us updated on how that goes.

Art

Replied by Denise E from Crescent City, CA on 03/06/2023

Ok Art, that is spendy stuff, but I will try and get it. Xylitol is a sweetner and not sure why they would put that in a nasal spray, but I've read it's safe to use in food/drink, or whatever, with my T2 Diabetes so I don't need to be concerned about that.

Thanks again, so much and I will let you know. BTW, I can't do all the supps in the protocol for memory loss right away so I am just trying the D and the Citicoline to start, I am also doing ALA, my magnesium citrate, and Lutein. I do collagen from Ancient Nutrition. I don't want to do too many things, and my foods provide a lot of nutrients but do believe I need to supplement.

I'll keep you posted for sure Art, Denise

Replied by Art from California on 03/06/2023

Hi Denise,

Xylitol in the sinuses has a couple of useful effects, it is anti inflammatory and it helps prevent allergens from sticking to the sinus tissues. It also has biofilm busting activity and overall its effects are complementary to the potent antimicrobial qualities of the grapefruit seed extract.

Here is a study that discusses how xylitol in just water as a nasal rinse works :

https://pubmed.ncbi.nlm.nih.gov/21994147/

Here is a relevant quote from the study :

' Xylitol in water is a well-tolerated agent for sinonasal irrigation. In the short term, xylitol irrigations result in greater improvement of symptoms of chronic rhinosinusitis as compared to saline irrigation. '

Good on the vitamin D because that is overall healthy for you anyway. I look forward to your updates!

Art

Replied by Denise E from Crescent City, CA on 03/07/2023

Thank you Art, love the PubMed studies, read a lot of those since I got into Ketogenic eating. I didn't know about the other benefits of the Xylitol so I will definitely get that for my sinus rinse instead of salt, I'll keep you posted.

Something in my 5 supps 6 counting the collagen (half what the dose is on the jug for now) are giving me weird, vivid dreams. Not nightmares, just things like going through the gas line, and I'm always younger, and I'm driving my old Buick I had 20 years ago. Just odd stuff. I'll keep up on my supps though and see if that changes, but I'm think either Citicoloine or ALA as I've never used that supp before.

Since I'm taking things to improve my brain, maybe that why, thinking/remembering too much. Thanks much, again, Denise

Replied by Art from California on 03/07/2023

Denise,

I would be more inclined to attribute that effect to the Citicoline rather than the ALA. If it isn't too bothersome, you should be able to continue it.

Art

Replied by Denise E from Crescent City, CA on 03/08/2023

I'm so sorry Art, I completely missed seeing the Vinpocetine. I looked it up and sounds very good but did you want me to just take that with my D, and if so, what dosage? Looks like 30mg is highest on Amazon?

Replied by Art from California on 03/08/2023

Denise,

This is a direct quote from my post on memory supplements :

' Studies show 30 mg/day as a good dose, and she started at 30 mg/day. Here is a link to two studies suggesting that Vinpocetine may be useful for the purpose '

Art

Replied by Denise E from Crescent City, CA on 03/09/2023

I have to check the prices but want to get the Vinpocetine, Lithium Orotate, Amla ordered today @ recommended dosages. Thanks much, Denise

PS I will read the studies on the Vin, as well as LO and Amla.

Replied by Art from California on 03/09/2023

Hi Denise,

Just a reminder that Amla is no longer part of the 5 supplement memory supplements, it was replaced by the Citicoline.

The five supplements are :

1. Vitamin D

2. Vinpocetine

3. Lithium Orotate

4. Citicoline

5. Melatonin

Art

Replied by Denise E from Crescent City, CA on 03/09/2023

Hello Art, I re-read your original article to your friend, and picked up on more info I didn't the first time through. I guess it's pretty clear why I've asked for help on EC, smiley face.

I wanted to tell you something I didn't mention before but I am weaning myself off clonazapam that I think probably has taken it's toll on my body. I only ever was prescribed 1mg dose 1 per day but took it since 1988 for Essential Tremor and anxiety. I am only down 1/4 tablet so far, but that's every day for a month so far, so I take .75mg a day.

I tried this once before and I think the doc pushed me to go faster by giving me .5 tablets so I am doing it myself this time because I know my own body better than he does. I may have had a TIA during that time, but no one is finding anything, or found anything that indicated that. The whole left side of my body went numb and the medics hauled me to ER. That was 2 Summers ago and my bod came back to life in under 3 days, except my left arm (this is all another story for another thread).

After my numbness attack, doc put me back on 1 mg clonazapam.

I wanted you to know because some of your protocol could help me off these darn pills, at long last. I'm not asking you for any feedback, I can see how much work, effort and help you are giving all of us. I just wanted you to know about that drug I am on, it's the only one thank goodness, except for Immitrex which only is used if I get a bad migraine which you already know those are all but non-existent at this early point in just part of the protocol.

I did get 3 more things ordered today, the Alma, LO, and the Lithium Orotate. I had to get a couple in different brands for expense purposes, but I read the labels, sound very straight up. Thanks much, again, Denise

Replied by Art from California on 03/09/2023

Denise,

Since you just ordered the Amla today, you should be able to cancel it as the Citicoline replaced the Amla. I explained this in the original post, but you must have missed it. The reason for the change is because studies for Citicoline were better than they were for Amla.

Art

Replied by Denise E from Crescent City, CA on 03/10/2023

I'll keep both of them anyway Art, and yes, I did fail to realize the Amla had been replaced. I am having worse tremors last 3 days for some reason, only changes being supplements, diet is still the same. I will narrow it down to see which could be causing it, or if any are at all. It could be the tremor has just gotten worse, no idea, yet.

If citicolene is doing it, then I'll have the Amla for backup. Thank you for getting back to me, I have a doctor appt this a.m. at 8:30 and plan to ask him if there are any labs I haven't already kept up on, ones that do an in depth look at deficiencies I may have. I'll let you know if we come up with more info, Denise

Replied by Art from California on 03/10/2023

Denise,

Here is a link to people discussing ALA and how it affected them :

https://www.drperlmutter.com/awesome-amazing-alpha-lipoic-acid/

One poster said the following :

' Martha Albertson Angela Martin5 years ago

100 mgs once a day in a multivitamin for about three years. The ALA worsened my essential tremor. It gave me dementia, ataxia and nystagmus. The decline was slow I eventually ended up housebound unable to even safely cross the street by myself. I surrendered my driver's license. I have since had my mercury fillings SAFELY removed by an IAOMT dentist. I am detoxing with a daily sauna and some Quicksilver products. '

It's just one anecdotal report, so take it with several grains of salt. What you can do is stop Citicoline or stop ALA for a week or two and if your tremor normalizes you will know which one is causing the problem. If you stop citicoline and the problem persists, ALA may be the problem. If you stop ALA and the problem persists, then citicoline may be the problem.

Art

Replied by Denise E from Crescent City, CA on 03/11/2023

Oddly enough, I'm not having the worse tremors this a.m. Art and I took all my stuff yesterday. I'll see how it goes and look for any signs that it could be the supps. I did get a good workout at the gym yesterday, and hadn't been doing my routine for 5 days, blamed it on weather but just got lazy.

As I mentioned, my foods were the norm, as well as the last 9 days of supps. Hard to really know but I'll keep you updated for sure. I think it's been 13 or 14 day now. Thanks for all your help, Denise

Replied by Art from California on 03/11/2023

Denise,

The jumping back into your exercise routine after taking 5 days off, may be the contributing factor.

Art

Replied by Denise E from Crescent City, CA on 03/13/2023

I'm off everything except my D-3 and Magnesium Art. I had the worst migraine (no aura or numbness) steady pain in right temple, and can't remember the last bad one. I took my immitrex and couldn't stand the pain an hour later so took 3 of my 200 mg ibuprofen, and that finally stopped the pain in about 2 hours. I kept ice on my head for just a few minutes, had to lie down finally, couldn't keep going and then suddenly I think the immitrex or ibu kicked in.

Yesterday a.m. I took nothing except my D-3 and mag, didn't want to stop those two as I don't believe they were the cause. I can't tell anyone it was the other 3 supps (citicolene, ALA, Lutein) but I was too afraid of it coming back to take anything else for now.

I'll let you know if I decide to try something more again Art, but honestly, I just feel unsure right now. I'm pretty good this a.m. Just having my decaf with turmeric and half dose of collagen, which never caused any issues. I'll be doing some more research to see what happened but for 70 years there's never really been a rhyme or reason for my migraines but this was a wopper. Any worse at all and I would have been at ER.

I broke down and took an antihistamine called Loratadine because when I went to ER they had to give me 2 shots of pain killer, and 3 shots of antihistamine to stop the pain, eventually knocked me out basically. Gave me one each hour or so but really don't remember that well.

Again, I really can't blame the new supps, could have been the weather, or just still going to have these migraines once in a great while, I am hoping if I must have one, it's only that often.

Replied by Art from California on 03/13/2023

Denise,

I understand. I'm glad you are better now. Please keep us updated on the path you decide to take.

Art

Replied by Lisa from TX on 04/06/2024

How much of the Citicoline should be taken and when?

Replied by Verona from Alabama on 04/27/2025

Hello, the updated link to Art Solbrigs protocol is not working now. Is there a way to find what the protocol is? Thank you!

Replied by Fred from Europe on 05/13/2025

Hi Art,

Vinpocetine is classified as a prescription drug in the European Union. Any suggestions for a replacement or perhaps that's the only one of the five supplements that actually works?

Fred

Replied by Art from California on 05/13/2025

Hi Fred,

If you have access to fecal microbiome transplantation (FMT), that should be an excellent replacement for the vinpocetine. If FMT is not available in your area, you can consider Ginkgo Biloba Extract (GBE) as one substitute. Here is a recent study discussing GBE for having synergy with the common AD treatment Donepezil/Aricept :

https://pmc.ncbi.nlm.nih.gov/articles/PMC11932902/

Here is a relevant quote from the link :

' The addition of Ginkgo to donepezil may yield superior cognitive outcomes and a greater decrease in plasma MDS-Oaβ compared with donepezil alone in amyloid PET-positive AD patients. '

This suggests the potential that GBE may have synergy with the other components of this memory regimen.

Also to further update the original article as regards the use of melatonin for memory is this newer study suggesting that melatonin may be superior to three drugs used for AD as discussed here in this meta analysis of 10 randomized, controlled trials (RCTs) :

https://pubmed.ncbi.nlm.nih.gov/38461503/

Here is a relevant quote from the meta analysis :

' The analysis included 10 randomized placebo-controlled trials with 4, 599 patients. Although melatonin and aerobic exercise for a short time were significantly more effective than donanemab, lecanemab, aducanumab and placebo in the primary analysis, there was significant heterogeneity. In the sensitivity analysis excluding exercise, melatonin was significantly more effective than donanemab, lecanemab, aducanumab and placebo, with no significant heterogeneity. '

Art

Replied by Fred from Europe on 05/14/2025

Hi Art,

Thanks for the detailed suggestions. My mom has an undiagnosed memory disorder. I’ve had her take Ginkgo (GBE) on and off for over a year, but haven’t noticed any improvement. For the past 1–2 months, she’s been taking Citicoline and Magnesium L-Threonate—no clear results yet, though it may still be early.

I’m not aware of any way to access FMT outside the medical system here, so that’s likely not an option. Melatonin does sound promising, especially given the recent data you shared. I’ll take a closer look at the meta-analysis and consider adding it to her regimen.

Thanks again.

Fred

Replied by Art from California on 05/15/2025

Hi Fred,

Please keep in mind that it took my friend almost a year of everyday use to get the benefits that she got. The changes were slow to see, but they were clearly noticeable at one year of taking the regimen faithfully. She had no diagnosis for her memory issue.

If she is already using Aricept, the addition of melatonin should be useful based on the synergy mentioned in the study.

Art

Replied by Hollyhock from America on 05/15/2025

There are also benefits of taking coconut oil 3 times a day as well. It was documented by a doctor who gave it to her husband with alzheimers disease.