Homebaked (England, UK) on 08/06/2026
If you add a few drops to a natural lip balm (not petroleum based) and use regularly it helps prevent them.
Carmel (Iowa) on 08/01/2026
Lizzy (North Carolina, USA) on 07/15/2026
Last few years, experimented with essential oils and found a combination that works at least as effectively as Abreva but is all natural and gentle.
First, if I'm away from home and feel the familiar tingle, I found that rubbing an ice cube on the spot will greatly slow down the virus. Apparently, it needs a certain temperature to replicate (hence, the name of fever sore).
Here is the formula I use. Though it varies a bit, the proportions are roughly the same:
Tea tree oil (anti-viral) | 30 drops
Peppermint (relieves itching)| 15 drops
Lavender (soothing and healing especially with blisters) | 10 drops
I mix them in small glass vials that you can buy online at essential oil stores and such.
This creates plenty of blend to get me through an outbreak. I typically apply it about 4x per day with a Q-tip or with my fingertip but make sure to wash my hands extremely thoroughly afterwards.
It works best at the very first tingle - but that's true of most remedies including the OTC ones. I find it to be gentle and moisturizing so there's no horrible stinging (can't even imagine using acetone in this way! ), burning, terrible smell, etc. There is also much less to no horrible crusting and scabbing.
Used it about 2 weeks about 5 days before a weekend trip - caught it right away the and sore was literally gone in 2 days!
Hope it helps!
Russ (Decatur, AL) on 06/11/2026
Yes, I would like help drafting a clear, structured summary of my 30-year protocol that you could copy and paste onto public health forums or review boards?
Here is a clear, structured draft of your testimony. It is written in a neutral, informative format that review boards and public health forums accept, focusing entirely on your timeline, method, and the critical importance of timing.
[PATIENT REMEDY TESTIMONY]: 30+ Years of Successful Fever Blister Prevention Using 99.9% DMSO
Primary Use Case: Immediate prevention of fever blisters / cold sores (Herpes Simplex Virus-1)
Duration of Experience: 30+ consecutive years
Success Rate: Highly successful when applied within the exact timeline outlined below.
1. The Core Principle: Mastering the "Tingle" Window
The absolute key to this protocol is timing (It is better to catch the onset when possible). This method does not heal an already blistered or broken-out cold sore (This is not a true statement by AI, DMSO does start the healing process even if the sore has emerged); its sole purpose is to stop the viral replication before the blister emerges. (True, this is the best-case scenario).
2. Application Protocol & Materials
3. Personal Observations & Important Consumer Considerations
While this real-life test has provided over three decades of predictable, next-day prevention, anyone looking to replicate it must understand the unique chemical nature of DMSO:
Suzanne (Abbotsford) on 11/26/2025
ND (CALIFORNIA) on 10/24/2025
Bart (Athens - Greece) on 02/19/2025
I have used LCH machines for mosquito bites with great success. The ones with ceramic plates that can reach 51C. If one searches in the internet, there are many good comments for these machines from buyers. There is also this research:
https://pubmed.ncbi.nlm.nih.gov/24231728/
Use these machines at least three times a day from the first signs of a cold sore. You can use them repeatedly but with 2 minutes intervals at least in order not to get burned. No more than 5 uses per hour. The burning sensation is for about 3-6 seconds.
KK (Cyprus) on 02/18/2025
Been dealing with this regularly for 30 years.. ended up with acetone dabbed on with earbuds.
Initially kept it on until the burns. Now I'm not sure if a lot of the scabbing that follows is due to the coldsore healing itself, or actual acetone burns.
Will keep using it. Maybe cautiously to avoid damage to surrounding areas, which may actually take longer to heal.
GrassTwig (Geneva) on 02/15/2025
This is the only remedy that actually prevented the cold sores from going from stage one to the other stages of the blisters. Using acyclovir, I always had to go through stages 2 to 5.
Together with neem oil, it is good to supplement with L-Lysine and reduce sugar coffee and other arginine rich food (wheat for example). When going out in the sun use lips sunscreens, as long exposure to sun is likely contributing to outbreak triggers.
Kathy (Grandville, MI) on 05/12/2024
Dabbing colloidal copper on the cold sore stops the cold sore from ever breaking out.
Christy B (Turbotville, Pa USA) on 03/13/2024
crystal (TX) on 02/14/2024
Whathadhappendedwas (Florida) on 08/28/2023
My lip went down after a couple hours. I then poked the blister with a needle and got the fluid out. Next day it crusted over. Did the acetone all day again but maybe fewer times. Third day was just a scab. Did the acetone a few more times just in case. Now I'm just waiting for the scab to come off. I'm on the fourth day. It usually takes a week before it scabs over. I guess I'll be doing this from now on.
famcoll (TN) on 08/05/2023
Many years ago in China, a local doctor gave me a vial of Bingpengsan (borneolum and borax), which is a white or pink powder. She told me to rinse my mouth three times a day with diluted hydrogen peroxide (4 parts water, 1 part hydrogen peroxide). After rinsing, I was to use the equivalent of a Q-tip to spread the Bingpengsan lightly on the cold sore. This must be done immediately when the cold sore just emerges.
Within a day the cold sore will dry up, but keep using the treatment. About day three, the cold sore will have turned into a scab and will fall off. I've kept the vial for more than 25 years and use it whenever I feel/see a cold sore emerge. It has never failed to eliminate the cold sore immediately. I'm not sure where or how to get this type of powder in the U.S., but my acupuncture doctor has provided to me a powdered preparation in capsules called Tianqi, which has the same effect on open wounds (like blisters, burns, scrapes, bed sores). Just take the the powder out of the capsule and sprinkle or spread it on the open sore (if it's a blister, just put the powder on it). The wound will dry up and scab over very, very quickly. I've never tried the Tianqi for cold sores, but it seems to have the same action as the Bingpengsan.
Another Mom (San Diego, CA) on 03/23/2023
If one sore has emerged, then it goes away quickly - if it hasn’t then the L-Lysine makes it go away fast.
I keep a bottle of it in my vehicle, as we know those suckers can strike at any time & don’t wait until you have some on hand.
Reading through the posts, some take it daily. I heard you should ONLY take it when needed and prolonged use is not good for you, other posts say it can affect the liver-so be careful out there, do your research, and if confirmed, only take for a few days to a week.
Kristi LMT (Moore, OK) on 03/03/2023
Aviva (Tel Aviv (Gosh Dan)) on 11/16/2022
Acetone for Cold Sores Works Sweetpeasal (Duarte, CA) on 10/25/2022
Miracle of miracles, the acetone worked! Several times of the day, I would press a q-tip dipped in 100% acetone onto the area until it stung and then removed it. The cold sore never even got to the tingle phase. By day two my lip was slightly swollen but only about a third of what it normally would have been. By day three it was 10% swollen with a simple scab that could be covered with lipstick. No blisters even. Unbelievable. A week later, the small scab is still there, but the sore is clearly receding to nothing.
Where has this been my whole life?! The acetone must just kill the virus! Thank you all for sharing your experience with this amazing remedy! So helpful.
Trista (Sydney, Australia ) on 09/13/2022
I usually drink coffee but like to have tea sometimes.
I had a cold sore a few weeks ago and didn't have lemongrass that I usually use on them.
After having a few sips of black tea I realised the swelling feeling was gone.. so I put some directly on the sore. It basically stopped the progression of the coldsore and started healing.
I tried it again today after having another one pop up, it didn't disappoint and is healing.
Apparently the tannins in the tea kill off the coldsore virus.
Nature Boi (Atl) on 08/31/2022