Dee (Florida) on 02/23/2024
Sammy (North County San Diego) on 01/12/2024
Thank you for sharing your recipe and your knowledge.
judith (USA) on 12/10/2023
Edy (CA) on 10/24/2023
Art (California) on 10/23/2023
To add further corroboration to the idea that melatonin helps to promote healing of spinal cord injury, this new study (10/23/23) shows various methods that melatonin utilizes to do this :
https://www.ibroneuroscience.org/article/S0306-4522(23)00460-8/fulltext
Here is a relevant quote from the study :
' SCIs were simulated in mice by inducing cord contusion at the T9-T10 vertebrae and causing inflammation in primary spinal neurons using lipopolysaccharide (LPS). The findings of our study demonstrated that Mel treatment effectively promoted neuromotor recovery through multiple mechanisms, including the reduction of neuronal death, suppression of astrocyte and microglia activation, and attenuation of neuroinflammation. Moreover, Mel therapy significantly upregulated the expression of SIRT1 in both spinal cord tissues and spinal neurons of mice. Additionally, Mel exhibited the potential to mitigate neuronal mitochondrial dysfunction by modulating the levels of Drp1 and TOMM20, thereby addressing the underlying factors contributing to this dysfunction. Furthermore, when SIRT1 was downregulated, it reversed the positive effects of Mel. Overall, our present study suggests that Mel has the capacity to modulate the SIRT1/Drp1 pathway, thereby ameliorating mitochondrial dysfunction, attenuating inflammation and apoptosis, and enhancing neural function subsequent to SCIs. '
Art
Edy (California) on 10/23/2023
How many mg do you recommend to start with and how far to go up to, in other words dosing. I have the cream that goes up to 200 mg in 1/2 tsp. Thanks, Edy
Frances (Cabarlah, Qld.) on 10/22/2023
Art, what dose melatonin do you suggest for those who can take the supplement? In some countries like Australia, one needs a doctor's prescription to obtain melatonin; sometimes up to 3mg can be found on eBay.
Toni (Philadelphia, PA) on 10/21/2023
The doctor told me my spine arches out like ). The coccyx is like a "shelf" because of this. He blamed this on the way I sit. I sleep on my back and must find the right "spot" to lay to prevent pain in the coccyx. Would the melatonin help me?
Rose (Moraga, CA, USA) on 10/20/2023
What brand of topical melatonin does Art Solbrig recommend?