Art (California) on 11/02/2023:

I have not seen any human studies using nattokinase or other fibrinolytic enzymes specifically for varicose veins so I can not recommend it for that purpose. However, there are web based health promotion sites that do suggest that nattokinase may be useful for varicose veins based on anecdotal evidence. Here is a typical example :

https://www.clinicaleducation.org/wp-content/uploads/argfocus_200811_nattokinase_web.pdf

Here is a relevant quote from the site:

Back in 2002, we theorized that by dissolving branched fibrin—which coagulates prior to full clot formation— nattokinase might prove uniquely helpful in a range of disorders in which hypercoagulation is involved. This includes atherosclerosis, infertility, high blood pressure, dysmenorrhea, fibromyalgia, deep vein thrombosis, varicose veins, hemorrhoids, and ischemic strokes. We also suggested it would prove helpful in chronic infections, where the body lays down fibrin in an attempt to seal off harmful pathogens. Finally, we concluded that nattokinase could be helpful in slowing many age-associated illnesses, since high fibrin levels create local pathology and ischemia, and block nutrient and oxygen delivery in microcirculation. Six years later, with nattokinase widely in use, firsthand clinical reports from doctors around the country support our hypotheses and the enzyme’s impressive record of efficacy and safety in a wide range of disorders.

Based on the established safety profile of nattokinase, it seems worth discussing it with your doctor to see if he will also suggest it as in the article, for varicose veins.

Regarding vitamin K2, I am not aware of any studies confirming efficacy for varicose veins, but vitamin K2 has shown benefit for the vascular system in general as has nattokinase. Your doctor would have to approve their use for your safety and to make sure that they are compatible with all medications you are taking.

Thank you for your inquiry!

Art

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