Mery (Hendersonville, NC) on 03/25/2024
https://www.sciencealert.com/parkinsons-may-be-caused-by-a-common-aquatic-bacterium
Thank you so much.
Replied By Art (California) on 03/25/2024
Here is a link to the actual study done about 11 months ago :
https://www.frontiersin.org/articles/10.3389/fcimb.2023.1181315/full
They are looking at three specific strains of the Desulfovibrio bacteria (DSV) :
1. D. desulfuricans
2. D. fairfieldensis
3. D. piger
The study was done in worms, which may or may not translate to humans. In any case, there are specific antibiotics that can target these bacteria as well as supplements that also target these bacteria, but to date, no human studies have been done to test this theory.
As an example of a supplement that works against these strains, inulin made from agave has a negative impact, but it has not been shown which strains of Desulfovibrio it works against as discussed in this article :
https://www.sciencedirect.com/science/article/pii/S0022316622088551?via=ihub
Here is a relevant article quote :
' Desulfovibrio were depleted 40% with agave inulin compared with control. Agave inulin tended (P < 0.07) to reduce fecal 4-methyphenol and pH. Bivariate correlations revealed a positive association between intakes of agave inulin (g/kcal) and Bifidobacterium (r = 0.41, P < 0.001). Total dietary fiber intake (total fiber plus 0, 5.0, or 7.5 g agave inulin/d) per kilocalorie was positively associated with fecal butyrate (r = 0.30, P = 0.005), tended to be positively associated with Bifidobacterium (r = 0.19, P = 0.08), and was negatively correlated with Desulfovibrio abundance (r = −0.31, P = 0.004). '
Again, no human studies to support the use of agave inulin for PD.
As far as a treatment for PD, given that the actual cause or causes of PD are still not known, there is no likely cure for the disease, only treatments to help reduce symptoms. The downside to the mainstream treatments for PD is that they can have significant side effects. The treatment that has been the mainstay for PD for about 50 years is the combination drug, Carbidopa /Levodopa also referred to as Sinemet.
One of the supplements that has shown significant anecdotal evidence against PD is vitamin B1 at higher dosing levels. Again, no human studies to support its use.
My personal opinion is that one of the best natural treatments for PD is fecal microbiome transplantation (FMT). Unfortunately, FMT is only approved for two diseases in the United States, neither of which is PD. In order to get FMT for PD, you might have to travel to China, which is much more progressive than most countries when it comes to FMT. This would be cost prohibitive for most people. FMT is already proven safe in human studies, but is still only approved for Clostridioides difficile, commonly referred to as C.diff, a bacterial infection of the gut which can be life threatening in severe cases. It is also approved for IBS in the US. In both diseases, it is normally only used when the standard treatments have failed to be effective.
Art
Replied By KRIS (Australia) on 03/26/2024
cheers and good luck
Replied By Kanpure Mailo (US) on 03/27/2024
https://www.brighteon.com/8920f5f9-2c7a-4d4f-a2e4-1b26b338bb52
EC: Description per url above
In this podcast episode, Dr. Ardis discusses strategies for preventing and treating Parkinson's disease. He highlights supplements like taurine, selenium, and a foreign protein cleanse as potential aids in managing the condition. Dr. Ardis explains the symptoms of Parkinson's and common pharmaceutical drugs used for treatment, cautioning against relying solely on medication due to potential side effects. He explores natural solutions for managing symptoms and recommends supplements like acetyl cysteine, taurine, and quercetin. Additionally, Dr. Ardis discusses the potential benefits of nicotine in treating Parkinson's disease and suggests considering nicotine patches or gum as part of a treatment plan.
Replied By Art (California) on 03/28/2024
The Michael J. Fox Foundation (MJFF) helped fund a study using nicotine patches on people with PD and the study found nicotine patches to be less effective than placebo as discussed here :Here is a relevant quote from the study :
' One-year transdermal nicotine treatment did not slow progression in early Parkinson's disease. (Funded by the Michael J. Fox Foundation for Parkinson's Research and others; ClinicalTrials.gov number, NCT01560754; EudraCT number, 2010-020299-42.) '
Although the above study showed no ability for nicotine patches to slow disease progression in people with early stage PD, there are anecdotal reports suggesting it may help improve certain symptoms.
There is currently no cure for PD, but there are medications and supplements that can help alleviate some symptoms. PD is a very complex disease in which the cause is still undiscovered. Medications are not thought to slow disease progression, but given the activities of some supplements, they show potential to slow disease progression through reduction of oxidative stress, inflammation and antiapoptotic effects.
Art
Replied By Cindy (Illinois, USA) on 03/28/2024
FYI - nicotine is niacin. the nicotine in tobacco was renamed so it could be demonized.A little niacin with a little diatomaceous earth for the small amount of bioavailable silica it contains that is needed to facilitate niacin uptake is plenty.
The body possesses its very own nicotine/niacin handling system.
If I had to guess, I'd say that a little diatomaceous earth would provide more than enough silica, making up for soil depletion, to make the niacin in modern nutrient-starved food more available to the body.
It's not difficult to understand that the vegetables purchased today are nothing like the vegetables purchased 50 years ago. Some only barely even qualify as food.