While it is encouraging to discover that B3 vitamin appears to be helpful in effecting the course of Alzheimer's positively, yet not completely to the point of reversal or even as a prophylactic, one has to ask the question why there is so much emphasis on one agent, when in fact all chronic diseases are a result of multiple deficiencies. Can people not think in multiple factorials? Or is it mental laziness that prompts people and scientists to want single solutions for diseases which they have decided are a single entity caused by a single factor or agent. All agents that will help to energize brain cells, such as D ribbose, creatine, MSM, coconut oil, coQ10, should be taken into consideration. One must also remember that toxins such as aluminium, fluoride and mercury are neurotoxic and probably play a major role in causing mental deterioration. If such factors are ignored, the research done on any disease becomes null and void and of no value what so ever.