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Paul (NY, NY) on 09/15/2006
5 out of 5 stars

You have nothing written about LDN. I was on the floor drooling this new years day from a bad ms attack, i could not swallow, speak,stand,walk etc. I started LDN www.ldninfo.org and within a months time it reversed all my symtoms and after 8 months im now on my way to walking normal again. LDN works and has been the most effective drug I have ever taken for my MS, my MRI from 2002 had 11 lesions and my MRI from last month after being on LDN for 8 months had zero (0) lesions on the brain. email me for an article I wrote on LDN. email:[email protected] and paulnicholasonline.com
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Replied By Pat (London, England) on 10/26/2008

I have a friend. he is 42 been ill for 2 years now. just released from 4 month stay in london hospital. he has been disagnosed with progressive ms. I have never heard of ldn. what is it. and where can he buy it. many thanks pat .x

EC: Low Dose Naltrexone.. http://www.ldninfo.org/

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Replied By Dudley (Virginia Beach, Va) on 12/15/2009

Naltrexone is a cheap generic pharmaceutical approved by the U.S. Food and Drug Administration for treating drug and alcohol addiction. In very low doses, it is proving to be remarkably effective in treating multiple sclerosis--with minimal side effects and at a price anyone can afford.

 

For more information about Low Dose Naltrexone (LDN), visit

http://tinyurl.com/intro-to-ldn

The above site features links to LDN-related research, case histories, discussion groups, books, articles, and video clips.

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Replied By Hristinad (New York) on 03/23/2016

Where can I buy LDN, or a doctor must prescribe it?

Replied By Rsw (Oh) on 03/24/2016

Hi Hristanad,

LDN is an inexpensive prescription drug in the US. It is gaining recognition among doctors and many will prescribe it. If, however, you can't get a prescription, you can buy it overseas, online. There are also several doctors in the US who will prescribe after a phone consultation. You can buy 50mg pills that can be diluted with 50ml of distilled water to make your own solution, where 1ml of solution equals 1mg of LDN. Measure the dose with a $1,5ml dropper, available at any drug store. Very easy to do. It will keep in your refrigerator for up to 90 days. The new updated, comprehensive book, "The LDN Book" by Linda Elsegood is available on Amazon. If you join the LDN Yahoo Group and ask how to get some, the members will give you details about where you can buy it. I'm not sure that I can post it here. If you look on the www.ldninfo.org site, it will give you a list of reliable compounders in the US to use if you get a prescription and the Yahoo LDN Group address. My doctor told me LDN would be very helpful for my autoimmune problems, and to try to get some because she wouldn't prescribe it off-label. I buy mine overseas for the past six years and have never had any problems, and about half of the 12,000 members also buy their own. I think you can google "buy LDN" and you will see some sights, but most buy from the one run by Ian, who also takes it himself and donates to the LDN community. It does not come from China. If you have any further questions, please join the Yahoo Group that is listed on the LDN site listed in this post, and you will be welcomed and your questions will be thoughtfully answered. By the way, for the Crohn's people here, there are several posts right now from experiences of member users, about the current research and Dudley(the moderator) has posted links to first-hand accounts from other Crohn's users, and many links to research and helpful information. LDN is completely non-toxic, taken by mouth, with no side effects except possible short lived sleep problems, and that can be remedied by taking it in the morning. It is helpful with many autoimmune diseases, including Crohn's, IBS, Hashimotos, RA, (many others listed on the LDN site)by modulating the immune system, not killing it, is extremely helpful for MS, and mitigates the damage to healthy cells in cancer treatment. Some have successfully used it with other supplements and/or allopathic or holistic treatments for cancer. Best wishes! You have nothing to lose and much to gain.

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Replied By Deb (Florida ) on 03/24/2016

LDN must be prescribed by a MD & comes from a compounding pharmacy. Around $20 a month. I think you should start low to see how you react 1 to 1.5 mg, then 3 mg, then 4.5 mg if it doesn't bother you. It makes me VERY dizzy, then nauseous. Good luck!
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Replied By Tom (Los Angeles, California) on 03/24/2016

Hi,

I am also looking at LDN to treat my daughter diagnosed with Crohn's disease.

I have heard good things about LDN to treat gut issues.

Please share all the details about LDN if anyone has used it to cure their gut issues.

Thank you. Tom

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Replied By Deb (Florida ) on 03/24/2016

LDN must be prescribed by a MD & comes from a compounding pharmacy. Around $20 a month. I think you should start low to see how you react 1 to 1.5 mg, then 3 mg, then 4.5 mg if it doesn't bother you. It makes me VERY dizzy, then nauseous. Good luck!

Google Burt Brekson MD PHD.. Dr. Brekson sen uses LDN & IV Alpha Lipoic Acid for everything, cancer, MS. Start low 1 to 1.5 mg, then 3 mg, then 4.5 mg. call a compounding pharmacy ask if anyone in your area prescribes it, they'll know. It makes me very dizzy.

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Replied By Rsw (Oh) on 03/24/2016

Hi Tom,

The moderator of the Yahoo LDN site has given me permission to post his page on Crohn's here. He is very generous with his knowledge and time. I think you will find it helpful. Best wishes.

https://sites.google.com/site/dudleyslowdosenaltrexonesites/treating-crohn-s-with-ldn

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Replied By Rsw (Oh) on 03/25/2016

Dudley's page can be found about half way down this page that displays. There are also other LDN sites listed.

The one caveat I didn't mention on my current post that is important, is that LDN can be taken with ANY other drug, including steroids during flares, if necessary, but CANNOT BE TAKEN with OPIATE based drugs. They both compete for the same receptors and LDN will always win, which could throw an opiate user into an unexpected and potentially dangerous withdrawal. LDN will block the effect of an opiate. If surgery is anticipated where opiates will be used afterwards for pain, LDN should be discontinued a few days before the surgery or another kind of pain reliever needs to be used for a few days.

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Replied By Heather (Cincinnati, Oh) on 02/13/2017

I find LDN therapy for MS interesting. I have been on 2 mga twice a day everyday as it's in combination with my pain med. I actually notice more pain within 45 mins of taking it. I was diagnosed at 16 and I am now 32 so being so young and independent I sought out less acceptable ways of dealing with effects of MS. (i.e.) cocaine, which actually worked, I had no symptoms, amongst other dumb street drugs that numbed the depression and helped me block what was going on with my body.

Long story short when I wised up I found that the crap the docs gave me was making me worse so I sought out natural alternatives and I have felt much better without the injections and percocet and zoloft etc. I happened upon this H2O2 therapy and am going to try it along with all my supplements. The biggest thing through it all that I want to try and eliminate is the pain I experience so hopefully this helps and I can get rid of pain meds even with LDN altogether

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Replied By Rsw (Oh) on 02/17/2017

Hi Heather,

I have been taking LDN for more than six years for autoimmune problems. When you take the LDN, it will block your opiates and opiate receptors for four to six hours, which may be why you experience an increase in pain after taking it. It is during the next 18 a 20 hours that LDN will make your body think it is in short supply of these, and it will make more of both. This is usually where the healing is found, especially with MS. If you take LDN more than once in any 24 hours, the blockade will begin again and interrupt the healing time. May I suggest you try taking 3 mg. LDN once a day, and see how it goes? You could then experiment with 4.5 mg. once a day, but if you experience any muscle cramping at 4.5 mg, which sometimes happens at this dose with MS, then go back to 3 mg once a day. I hope you have joined the Yahoo LDN Group with over 13,000 members who take LDN, about half for MS. They can give you their personal experiences and guide you with what has worked out best. Wishing you relief from your pain soon. Best wishes!

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Replied By Rsw (O! For This Reason.) on 02/17/2017

Hi Heather,

I forgot to mention that if you are taking opiate based pain medicine, the LDN will block it, which also may be why you feel more pain after taking the LDN. This has the potential of throwing a person who is dependent on the opiate pain meds into a dangerous withdrawal. The ONLY thing that LDN should NOT be taken with is opiate based drugs, for this reason. Some people take pain medicine (Tremadol - sp?)in the morning, and LDN at night, 12 hours apart, and this seems to work for them. I would join the LDN Yahoo Group to get specific information about this from people who use it this way. LDN seems to work better for people with MS when they take it at night, between 10PM and 2AM.

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Replied By Jb (Tx) on 08/06/2018

When taking LDN, you work up from a dosage of 2 mg to 4.5 mg. If you feel dizzy, nauseous, or get headaches at 4.5mg, try taking your dosage back down to 3 or 3.5mg. You've arrived at your correct dosage when you feel good again. Very small people or those with poor liver function can't handle 4.5mg. Many people do well on 3mg.
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Replied By Rsw (Oh) on 08/06/2018

3mg. of LDN is often recommended for those with MS due to spasticity problems in some at 4.5 mg. If muscle cramping or spasms occurs at 4.5mg/day, reduce your dose to 3mg/day and see if you feel better. You will still reap the benefits of LDN.
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