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Sarah (Toledo, Ohio, United States) on 02/12/2013
0 out of 5 stars

I'm currently six months post partum and decided to start taking Grape Seed Extract for general health and younger looking skin. I was told to take 1mg for each pound I weigh (120lbs/120mg). The pills are 100mg each, so I was taking two a day with the understanding that excess would be excreted through urine. That day I started having heart palpitations, severe night sweats and anxiety/depression spells. This continued for two weeks (I thought it might be an adjustment period) before I reduced to one pill a day (100mg). The issues continued. I then stopped taking the GSE and all symptoms disappeared by the next day. I waited a week and tried it again. All negative symptoms came back in full force. In all my research on the internet, I'm not finding anyone with any issues like this regarding grape seed extract. I have two theories regarding my reaction and wanted to hear everyone else's feedback.

1. I'm thinking I might have post partum depression and the grape seed extract is amplifying it.

2. I had an epidural and petocin during my labor and my body is reacting poorly to all those drugs leaving my system.

These are merely guesses.

Age: 32, Weight: 120, good general health - no diagnosed issues, moderate exercise and a fairly healthy diet consisting of many fruits, vegetable, minimal meat and minimal processed foods. I do have alcoholic drinks almost every night (typically 1-3).

Thanks all!

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Replied By Timh (Louisville, Ky, Usa) on 02/13/2013

Sarah: GSE doesn't actually "detoxify" a free radical, but simply sequesters or mobilizes it to the liver for detox. I have had similar side effects from the antioxidant Lutein. Your symptoms suggest inadequate liver detox. Try supplementing NAC, Selenium, and 3mg Melatonin before retiring. Milk Thistle Seed Extract may also be necessary.

There is a wide range of antioxidants the body needs so I would also suggest dropping the G. S. For an "antioxidant complex" (which may contain some G.S.). Vit-A, E work well with Selenium and NAC. Zinc and Niacin help with the alcohol detox.

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Replied By Rosanne (Toronto, Canada) on 02/14/2013

Are you using Grape Seed Extract, or Grapefruit Seed Extract? They are two different things.
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Replied By Sarah (Toledo, Oh) on 02/14/2013

Tim, thank you for your suggestions. Rosanne - It is Grape seed extract I was taking.
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Replied By Octagon (Chicago, Illinois) on 02/28/2013

You may have gotten hold of a contaminated batch. Perhaps trying another highly rated brand would make a difference.
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Replied By Snowbell (Minneapolis, Mn) on 07/09/2013

Just wondering if you ever tried taking Grapeseed extract again. I have had some anxiety issues with possibly Grapeseed extract as well but never find anything online when I try to research.
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Replied By Kat (Gj, Co) on 01/05/2014

Number one I suggest you you address your alcohol consumption. The amount you listed is excessive and terribly hard on your liver. I know from personal experience and that of thousands of others that when asked about our alcohol consumption we down play it, if that is what you've done then I suggest you contact Alcoholics Anonymous (AA) at your convenience. Your child deserves a sober mother and you deserve to be conscious and aware of your life. It passes quicker than you think my friend!

I was a young mother to three when I began my journey with AA. It's been 26 yrs and I love my life. This site is a great place to start your search towards health, but until you stop poisoning yourself with alcohol you chances are slim for long term good effects.

God Bless You! Kat

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